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Re: Onconova

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Hi -- Thanks for the post. It's always good to know about new

drugs coming along. Helps keep my optimism in good form. Take

care. Kathy, dx 5/03

> Last night I had the pleasure of attending a presentation by Dr.

Goldman, a British CML specialist now doing a year of CML

research at NIH. The talk was sponsored by the Leukemia and Lymphoma

Society.

>

> The presentation was a general history of the discovery of bcr abl

and therapies through the years with very interesting specifics

charted out including the way the disease progresses and the various

drugs and how they control it and to what degree they work.

>

> At the end of his talk Dr. Goldman said that IM, AMN 107 and BMS

are the hot new drugs now but that there's a new one coming up that

is of great interest -- ON 012380 by a company called Onconova in

Delaware. Perhaps someone has written about it before but I don't

read every post. Anyway, you can read about it on their website:

www.onconova.com. It's active against the mutation T351i and uses

peptides produced by leukemia cells but that are not part of the

leukemia itself.

>

> L

>

>

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