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Last night I had the pleasure of attending a presentation by Dr. Goldman, a

British CML specialist now doing a year of CML research at NIH. The talk was

sponsored by the Leukemia and Lymphoma Society.

The presentation was a general history of the discovery of bcr abl and therapies

through the years with very interesting specifics charted out including the way

the disease progresses and the various drugs and how they control it and to what

degree they work.

At the end of his talk Dr. Goldman said that IM, AMN 107 and BMS are the hot new

drugs now but that there's a new one coming up that is of great interest -- ON

012380 by a company called Onconova in Delaware. Perhaps someone has written

about it before but I don't read every post. Anyway, you can read about it on

their website: www.onconova.com. It's active against the mutation T351i and

uses peptides produced by leukemia cells but that are not part of the leukemia

itself.

L

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