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Hi all,

I just got my latest PCR results. Undetectable in one million! I feel much

better as they said that I was slightly detectable last time. I see everyone's

notes, but sometimes find it hard to reply as I am quite busy. I do keep up

with all the news. My mom is having an angiogram on Thurdsday. If all goes

well I will be leaving for Kansas City, KS on Tuesday. Anyone in that area,

please e mail me at: ornurse954@.... Maybe we cna get together while I

am there.

I will be in Portland, Or. from August 20 thru the 26. Will anyone be there?

If so, let me know.

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What is important is that the 121,000 is down from 210,000. The .35 log

reduction, equal to a ratio of .44, which means your have a little less than

the average patient at dx. You dr didn't perform cytogenetics and FISH from

the bone marrow ?

Marcos.

On 7/3/07, rmtkaholyfield <no_reply > wrote:

>

> I received the results from my test and I need some help understanding

> what they say.

> The test is a BCR/abl, mRNA. From my peripheral blood.

> My normalized ratio was 121,000

> It represents a .35 log reduction from the average patient's level at

> diagnosis.

> Previous specimen Date 4/17/07 (Peripheral Blood)

> Previous Result: 210,000

> Test was performed at Mayo Medical Laboratories.

>

> I was dx 3-15-07 and have been on Gleevec 400mg. since 4-12-07.

>

> My Doctor now wants to do another test in a month on both the blood

> and bone marrow aspiration. He didn't do a very good job explaining

> why it's need, what was wrong with the latest results, and what it all

> means. Can anyone give me some opinions?

> Thanks

>

>

>

--

Marcos Perreau Guimaraes

Suppes Brain Lab

Ventura Hall - CSLI

Stanford University

220 Panama street

Stanford CA 94305-4101

650 329 9920 x 305

650 630 5015 (cell)

marcospg@...

montereyunderwater@...

www.stanford.edu/~marcospg/

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Hi,

Since you were just diagnosed in April, this PCR test represents

roughly only 3 months of treatment which is much too early to really

get an idea of what's going on. At this early stage, a cytogenetics

test and/or FISH would probably give you a better picture of what's

going on.

You said that your doctor will be doing a bone marrow aspiration in a

month. I assume that he'll be doing a cytogenetics test on the

sample as well as a PCR but it's the cytogenetics test that you

really want to pay attention to as that will give a much clearer

picture of how your treatment is progressing.

Take care,

Tracey

>

> I received the results from my test and I need some help

understanding

> what they say.

> The test is a BCR/abl, mRNA. From my peripheral blood.

> My normalized ratio was 121,000

> It represents a .35 log reduction from the average patient's level

at

> diagnosis.

> Previous specimen Date 4/17/07 (Peripheral Blood)

> Previous Result: 210,000

> Test was performed at Mayo Medical Laboratories.

>

> I was dx 3-15-07 and have been on Gleevec 400mg. since 4-12-07.

>

> My Doctor now wants to do another test in a month on both the blood

> and bone marrow aspiration. He didn't do a very good job explaining

> why it's need, what was wrong with the latest results, and what it

all

> means. Can anyone give me some opinions?

> Thanks

>

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