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Hi ,

The fluid retention around the eyes (peri-orbital swelling) is most

likely Gleevec related. This is one of the notable side effects of

Gleevec and many people experience it. I also have recently had

below normal potassium and I've been supplementing with 595mg's of

potassium daily (it's also good for the heart.) If your doctor is

reluctant to prescribe a diuretic, then I'd ask him about taking

potassium. Sodium & potassium work together in your body to hold or

relieve you of water. It sounds like potassium would help with your

edema. Bananas and oranges are a good source of natural potassium.

Sometimes I've had sudden fluid retention and it was due to eating a

high salt meal. (I love Mexican food!) It took a few days to go away.

Have you had any muscle or finger/toe cramping? If so, then

calcium/magnesium helps with that.

Regards,

Gale Bacon

zero club #112

400mgs Gleevec

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Hi ,

Edema is very common with Gleevec. Have you tried natural diuretics

like coffee, tea, watermellon, grapes or cucumbers? I find if I

drink something that I'm not used to, like juice, then I'll go like

a race horse. If I drink too much, too often, then I get used to it

and it doesn't work anymore so I have to switch to something else

like tea or coke.

Gleevec does deplete potassium so it's not surprising you're low on

it but there are supplements you can get if you get too low. It's a

delicate balancing act though because too much isn't any better than

too little. You really have to monitor your electrolytes

regularly.

Take care,

Tracey

> I have a question. I wonder if any of you had an experience with

sudden

> fluid retention in the legs and feet? I had that happen within

the last few

> days. I became quite alarmed. I spoke with my oncologist and am

supposed to

> call back on Monday. I am not on any type of water pill which my

dr. is

> reluctant to prescribe. I have borderline low potassium

already. I had two nights

> of extreme swelling of my lower legs and feet with a sudden

weight gain of

> about five pounds. Today it is much better after being able to

put my feet up

> for longer periods of time over the weekend. About half of the

weight is

> also gone, but I feel swollen around the eyes more than usual

too. I'm a

> little concerned about kidney function. My oncologist said my

kidney function has

> always been good and didn't think this sudden fluid retention was

gleevec

> related. I tend to think otherwise. What do you think? What

could cause this

> to happen suddenly? I appreciate your opinion on this matter.

Thanks!

> in NY

> dx. 1/04

> 400 mg.

> Zero Club #756

>

>

>

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Guest guest

Hi.

In addition to adding potassium through natural nutrients there are other

nutrients that work well as natural diuretics including watermelon and dark

greens.

L

[ ] fluid retention

I have a question. I wonder if any of you had an experience with sudden

fluid retention in the legs and feet? I had that happen within the last few

days. I became quite alarmed. I spoke with my oncologist and am supposed to

call back on Monday. I am not on any type of water pill which my dr. is

reluctant to prescribe. I have borderline low potassium already. I had two

nights

of extreme swelling of my lower legs and feet with a sudden weight gain of

about five pounds. Today it is much better after being able to put my feet

up

for longer periods of time over the weekend. About half of the weight is

also gone, but I feel swollen around the eyes more than usual too. I'm a

little concerned about kidney function. My oncologist said my kidney

function has

always been good and didn't think this sudden fluid retention was gleevec

related. I tend to think otherwise. What do you think? What could cause

this

to happen suddenly? I appreciate your opinion on this matter. Thanks!

in NY

dx. 1/04

400 mg.

Zero Club #756

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Guest guest

I had two nights

> of extreme swelling of my lower legs and feet with a sudden weight

gain of

> about five pounds. Today it is much better after being able to

put my feet up

> for longer periods of time over the weekend. About half of the

weight is

> also gone, but I feel swollen around the eyes more than usual

too. I'm a

> little concerned about kidney function. My oncologist said my

kidney function has

> always been good and didn't think this sudden fluid retention was

gleevec

> related.

_______________________

Hi ,

I think that sudden edema is a concern with Gleevec....I know that

OHSU/Druker has mentioned it to patients....but I have not had a

problem, so can't remember the particulars about it.

I sometimes has leg swelling....just the feeling of 'tight skin'.....

like my 'body suit' is too small! : )

I do not have ankle swelling per se.

Dr. Druker has Rx'd Dyazide for me, and I use it occasionally (really

more for when I notice some ear discomfort from edema). He prefers

this to the usual diuretics (can't remember the name) because it is

more potassium sparing.....and then you aren't also dealing with low

potassium.

My local onc (a nice, YOUNG guy) was surprised....he told me that

ide was more of a blood pressure medication. I mentioned this to

Druker....and he said.... " well duh....it lowers blood pressure

because it reduces fluid/edema " . My local onc had no intention of

challenging Dr. Druker about this anyway.

And like other have mentioned, I try to eat some things that are

naturally diuretic....like watermelon, even now, almost every day.

Also I juice cucumbers....with carrots and celery and parsley. I do

believe that with diet you can offset or reduce many of the side

effects of Gleevec.

Hope your swelling is down soon.

Maui Nanc

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Guest guest

Hello:

As soon as I went on a higher dose of gleevec, I started to have some fluid

retention. The hematologist prescribed diazide quite soon as the blood

pressure also tended to be up. I've not had a problem with blood pressure or

fluid

retention. One problem,if I'm not careful, with diazide is a tendency to low

potassium.

Yes, I think fluid retention is due to gleevec, Sincerely, MJH

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Guest guest

Hi ,

Yes, as a matter of fact. My husband and I just got back from a Caribbean cruise

and during the cruise my husband felt that he was retaining more fluid despite

taking 2 lasix's a day and his usual supplements. His hands were visibly

swollen and stiff. When we got back the scale showed him weighing 7 pounds more

than when we left and that was over a week's time. Within two days he lost all 7

pounds and was spending a considerable amount of time in the bathroom. The

weight was all fluid retention and we're not sure why it happened. The food was

saltier than what we make for ourselves at home and of course we ate it three

times a day for 7 days. But still, he's had salty meals before with no apparent

increase in fluid retention and he was taking lasix. You would think that the

lasix would eliminate the excess fluid. Apparently it was accumulating faster

than the lasix could remove. I don't know if the salt air and water were factors

too. In any event, we're home and his body seems

to have returned to its " normal " state.

Adrienne

nchando@... wrote:

I have a question. I wonder if any of you had an experience with sudden

fluid retention in the legs and feet? I had that happen within the last few

days. I became quite alarmed. I spoke with my oncologist and am supposed to

call back on Monday. I am not on any type of water pill which my dr. is

reluctant to prescribe. I have borderline low potassium already. I had two

nights

of extreme swelling of my lower legs and feet with a sudden weight gain of

about five pounds. Today it is much better after being able to put my feet up

for longer periods of time over the weekend. About half of the weight is

also gone, but I feel swollen around the eyes more than usual too. I'm a

little concerned about kidney function. My oncologist said my kidney function

has

always been good and didn't think this sudden fluid retention was gleevec

related. I tend to think otherwise. What do you think? What could cause this

to happen suddenly? I appreciate your opinion on this matter. Thanks!

in NY

dx. 1/04

400 mg.

Zero Club #756

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  • 1 year later...

Margaret, I have been taking Bumex every other day since I started

on Gleevec in September. It works well.

Kris

DX 7/06

600mg GLeevec---

In , Margaret Peake <mpraymond@...>

wrote:

>

> can someone please tell me what you're doing for this? My face,

hands, feet are puffy. I've cut back on salt but it doesn't seem to

help much. Anyone on diuretics? What kind?

>

> Thanks much,

> Margaret

>

> diagnosed 10-1-06 with 128k WBC with Philadephia

> 11-13-06 9.1 WBC

> on 600 mg gleevec

>

>

> Margaret ,

> mpraymond@...

> margaret-raymond@...

>

>

>

>

>

>

>

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Hi Margaret

Drink lots of water, at least 4pts per day. Drinking

water actually reduces water retention, rather oddly.

It reduces toxins in the body by helping to flush

them out.. Prep H around the eyes does help but it's

quite greasy so best to use at night.

I too had this problem on 600mg when I was first dxd.

It's not fun and often it's the only thing people can

see that you have any sort of disease what so ever.

Ask your Onc - he's bound to be able to help.

Be well

--- Margaret Peake <mpraymond@...>

wrote:

> can someone please tell me what you're doing for

> this? My face, hands, feet are puffy. I've cut back

> on salt but it doesn't seem to help much. Anyone on

> diuretics? What kind?

>

> Thanks much,

> Margaret

>

> diagnosed 10-1-06 with 128k WBC with Philadephia

> 11-13-06 9.1 WBC

> on 600 mg gleevec

>

>

> Margaret ,

> mpraymond@...

> margaret-raymond@...

>

>

>

>

>

>

> [Non-text portions of this message have been

> removed]

>

>

________________________________________________________________________________\

____

Want to start your own business?

Learn how on Small Business.

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At 12:17 PM 11/27/06 -0800, you wrote:

>can someone please tell me what you're doing for this? My face, hands,

>feet are puffy. I've cut back on salt but it doesn't seem to help much.

>Anyone on diuretics? What kind?

>

>Thanks much,

>Margaret

Hi Margaret,

Dr. Druker prefers diazide, because it spares potassium. I use it only

occasionally, on an as needed basis. My edema is in my ear and vocal cords.

Because you have some edema in your feet, your doctor needs to make sure

you are not having any signs of congestive heart failure. But, yes, there

are others on diuretics because of Gleevec....and some use it

regularly....hopefully you will hear from some of them.

C.

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Margaret tryed to send to your e mail kicked back.Anyway I take Dandelion root

540mg tryed diuretics better luck with the root .diagnosed 12 -05 wbc154 fist

test 0 400 gleevec

[ ] fluid retention

can someone please tell me what you're doing for this? My face, hands, feet are

puffy. I've cut back on salt but it doesn't seem to help much. Anyone on

diuretics? What kind?

Thanks much,

Margaret

diagnosed 10-1-06 with 128k WBC with Philadephia

11-13-06 9.1 WBC

on 600 mg gleevec

Margaret ,

mpraymond@sbcglobal .net

margaret-raymond@ cherokee. org

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thanks for the info.. how often do you take it? I'll check at my local health

food store.

Margaret

Shipley <paulorkay@...> wrote:

Margaret tryed to send to your e mail kicked back.Anyway I take

Dandelion root 540mg tryed diuretics better luck with the root .diagnosed 12 -05

wbc154 fist test 0 400 gleevec

[ ] fluid retention

can someone please tell me what you're doing for this? My face, hands, feet are

puffy. I've cut back on salt but it doesn't seem to help much. Anyone on

diuretics? What kind?

Thanks much,

Margaret

diagnosed 10-1-06 with 128k WBC with Philadephia

11-13-06 9.1 WBC

on 600 mg gleevec

Margaret ,

mpraymond@sbcglobal .net

margaret-raymond@ cherokee. org

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Thanks, what mg dose of Bumex are you taking?

Margaret

dkaobj5 <jonesdjkj@...> wrote:

Margaret, I have been taking Bumex every other day since I started

on Gleevec in September. It works well.

Kris

DX 7/06

600mg GLeevec---

In , Margaret Peake <mpraymond@...>

wrote:

>

> can someone please tell me what you're doing for this? My face,

hands, feet are puffy. I've cut back on salt but it doesn't seem to

help much. Anyone on diuretics? What kind?

>

> Thanks much,

> Margaret

>

> diagnosed 10-1-06 with 128k WBC with Philadephia

> 11-13-06 9.1 WBC

> on 600 mg gleevec

>

>

> Margaret ,

> mpraymond@...

> margaret-raymond@...

>

>

>

>

>

>

>

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everyday dandelion is mild compared to bumex

paul Tn.

[ ] fluid retention

can someone please tell me what you're doing for this? My face, hands, feet are

puffy. I've cut back on salt but it doesn't seem to help much. Anyone on

diuretics? What kind?

Thanks much,

Margaret

diagnosed 10-1-06 with 128k WBC with Philadephia

11-13-06 9.1 WBC

on 600 mg gleevec

Margaret ,

mpraymond@sbcglobal .net

margaret-raymond@ cherokee. org

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Hi .....Just checking in with you. It is my last day of class...I am

in the Art and Architecture library. I usually have to scoot back to Salem

right after class because of my daughter, but next term I will be around a

little longer. so we should try to get together.

is still doing well,but is having a hard time getting up here for his

pcr because his company keeps sending him to LA.

Hope you are well....Rosemary

>From: Cogan <ncogan@...>

>Reply-

>

>Subject: Re: [ ] fluid retention

>Date: Mon, 27 Nov 2006 13:35:15 -0800

>

>At 12:17 PM 11/27/06 -0800, you wrote:

> >can someone please tell me what you're doing for this? My face, hands,

> >feet are puffy. I've cut back on salt but it doesn't seem to help much.

> >Anyone on diuretics? What kind?

> >

> >Thanks much,

> >Margaret

>

>

>Hi Margaret,

>

>Dr. Druker prefers diazide, because it spares potassium. I use it only

>occasionally, on an as needed basis. My edema is in my ear and vocal cords.

>Because you have some edema in your feet, your doctor needs to make sure

>you are not having any signs of congestive heart failure. But, yes, there

>are others on diuretics because of Gleevec....and some use it

>regularly....hopefully you will hear from some of them.

>

> C.

>

>

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