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Hi ,

I don't know if I can explain the blisters or not. Everyone I talk to has a

different

pattern with them. For me, 4 months after starting gleevec, I had a large patch

of

them on my shin. They were in a form of a cluster. They itched and hurt at the

same

time - just like chicken pox. They appeared to be bumps in the skin that held

water.

The blister would break and then they would scab over and then heal ---and then

flare

up again. This pattern kept up for quite a while. I also had individual ones

pop up

on my hand, shoulder and neck with an occasional one on my head

( in my hair). Once they popped, they would scab over and heal. Today, the ones

on my

shin rarely flare up but my leg looks like I have been burnt. It looks like a

red

scar. The area is from the ankle to the knee. On occasion I still get a few

single

ones that pop up, but go away. I have been on gleevec 400 mg since June of 2002.

The

longer I am on it, the less they appear. I know of some people who have had to

go off

of gleevec because their entire body was covered with them. One of my CML

friends in

Georgia is going on the BMS trial because he cannot tolerate gleevec and has

blisters

over 100% of his body. Mine have never been that bad.

I hope this helps.

Barb in AZ

Message: 3

Date: Fri, 30 Sep 2005 23:14:22 EDT

From: vegasrnjen@...

Subject: Re: Blister Sisters

Can someone explain the blisters? I am starting to have skin changes? 3

months into treatments. I have these tiny, clear looking things on my upper

chest/neck area. You almost cant see them but they are painful? I dont know if

this is the same as what you guys are talking about but I'd thought I'd see if

anyone ran into that as well?

Thanks for allowing me to ask.

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