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Diarrhea - MJ

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Hi MJ,

Imodium (loperamide), 2 pills once every morning usually works well for me,

and I use it most days. Sometimes I take it twice a day, but am leery about

doing so too often, for fear of developing tolerance.

Though I haven't been able to find data supporting this, I've been told that

the reason Imodium works for IM-related diarrhea, even in such low doses, is

is that it stimulates the very enzyme in the gut - C-Kit - that IM inhibits,

and C-Kit activity is involved in slowing gut motility.

Cheers,

R

> Date: Mon, 01 Aug 2005 12:43:02 -0000

> From: " dlielc " <MJHodor@...>

> Subject: eyebleeds, and diarrhea

>

> Hi:

>

> Yes, I also get the sharp ping in the eye, and then see the eyebleed.

>

> But I'd like to reintroduce the topic of diarrhea. Some of the new

> members to other lists are concerned about it. Does anyone know what

> about Gleevec causes it? And what should be done about it? Immodium?

> I still have to deal with this after all these years. Thanks, and hope

> the topic isn't too embarrassing. MJ

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