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Re: Visine products

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At 05:11 PM 7/31/05 +0000, you wrote:

>He said it was a vicious cycle....eyes get dry, you put in Visine,

>they dry up soon after, you put more Visine, they dry up again

>etc... He said that my eyes would grow accustomed or dependant on

>the drops and they would no longer make any tears of their own which

>I totally believed because that's what happened.

>

>Now keeping in mind that I was trying to fix a dry eye problem, not

>a Gleevec related eye problem so it's very possible that he could

>recommend Visine as a decongestant for a problem that was from

>Gleevec.

Hi Tracey,

Yes, with Gleevec this is a totally different problem.....it is not for dry

eyes.

It is for eyes that are tooooo wet!!

Actually they tested me for tear formation, which is an annoying test where

the

tech puts a little piece of blotting paper against the edge of the eye to

determine

how much you will 'tear' in a set amount of time......and she said my tear

formation

was about 3 times normal..............

plus they can see all the fluid on your eye, as we can also..........

so this was why he recommended the decongestant..........which is not

artificial

tears. I used to use it every AM as he suggested, but now all my side

effects are

subsiding and I don't seem to need it except occasionally, but then it

seems to do

the trick for me.

C.

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Hi again Tracey, and others on this subject. There's a long word called

tachyphylaxis which refers to what you and others have experienced.

Tachyphylaxis is " the diminution of a pharmacological response during the

continued or repeated administration of an activating substance.

Tachyphylaxis or receptor desensitization appears counterintuitive because

the addition of more of an activating ligand lessens the elicited response. "

(from wikipedia.org). It occurs with a number of medicines, though none more

so that the class of drugs called " alpha adrenergic agonists " of which

decongestants are one example.

Cheers,

R

> Date: Sun, 31 Jul 2005 17:11:11 -0000

> From: " Tracey " <traceyincanada@...>

> Subject: Visine products

>

> Hi Everyone,

>

> I just wanted to add my two cents here. Many years ago (pre-CML) I

> had a terrible time with dry eyes despite using every variety of

> Visine product known to man. I finally got fed up enough and saw an

> ophthamologist who told me not to use replacement tears anymore.

>

> He said it was a vicious cycle....eyes get dry, you put in Visine,

> they dry up soon after, you put more Visine, they dry up again

> etc... He said that my eyes would grow accustomed or dependant on

> the drops and they would no longer make any tears of their own which

> I totally believed because that's what happened.

>

> Now keeping in mind that I was trying to fix a dry eye problem, not

> a Gleevec related eye problem so it's very possible that he could

> recommend Visine as a decongestant for a problem that was from

> Gleevec.

>

> I guess it's a little like being told not to use sleeping pills to

> relieve anxiety but if you need help sleeping, then they could be

> appropriate? Does that metaphor make any sence to anyone?

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--I'll add my 2 cents to this one. I have this problem with nose

spray I have been addicted to it since I was in my mid 20s. It takes

more and more of it to work. If you don't use it all the time when

you become addicted your nose will stop up completely (no air at all)

except through the mouth. It can last for weeks before it gets

better. I've tried to quit using it but i never make it through the

night. I told the Dr. at MDACC that I was addicted to it and he said

probably over half of the Drs. and staff were also, because it is so

hot and humid in Houston. So I guess i will just keep on spraying,

its the only addiction I have left. Quit smoking over 5 years ago.

Shari from Kansas

- In , rrockef1 <rrockef1@m...> wrote:

> Hi again Tracey, and others on this subject. There's a long word

called

> tachyphylaxis which refers to what you and others have experienced.

> Tachyphylaxis is " the diminution of a pharmacological response

during the

> continued or repeated administration of an activating substance.

> Tachyphylaxis or receptor desensitization appears counterintuitive

because

> the addition of more of an activating ligand lessens the elicited

response. "

> (from wikipedia.org). It occurs with a number of medicines, though

none more

> so that the class of drugs called " alpha adrenergic agonists " of

which

> decongestants are one example.

>

> Cheers,

> R

>

> > Date: Sun, 31 Jul 2005 17:11:11 -0000

> > From: " Tracey " <traceyincanada@y...>

> > Subject: Visine products

> >

> > Hi Everyone,

> >

> > I just wanted to add my two cents here. Many years ago (pre-CML)

I

> > had a terrible time with dry eyes despite using every variety of

> > Visine product known to man. I finally got fed up enough and saw

an

> > ophthamologist who told me not to use replacement tears anymore.

> >

> > He said it was a vicious cycle....eyes get dry, you put in Visine,

> > they dry up soon after, you put more Visine, they dry up again

> > etc... He said that my eyes would grow accustomed or dependant on

> > the drops and they would no longer make any tears of their own

which

> > I totally believed because that's what happened.

> >

> > Now keeping in mind that I was trying to fix a dry eye problem,

not

> > a Gleevec related eye problem so it's very possible that he could

> > recommend Visine as a decongestant for a problem that was from

> > Gleevec.

> >

> > I guess it's a little like being told not to use sleeping pills to

> > relieve anxiety but if you need help sleeping, then they could be

> > appropriate? Does that metaphor make any sence to anyone?

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