Re: bone/joint problems

[Guest guest]

Hi Holly,

I don't post much, either, but your message caught my eye. I also have been

having extreme lower back pain and at times it is almost debilitating. I did

already have scoliosis before I was dx with cml, so I was at first attributing

aches and pains mainly to that. The pain in my lower back, however, has become

so intense at times, that I recently ended up in the e.r. with a morphine drip

just to get it under control.

It seems to go in cycles.

chris in mn

[ ] bone/joint problems

Hi everyone! I know I don't post much and its been a long time, but

I was wondering about something and was wondering if anyone here

would know anything about this.

I have been on Gleevec since August 2000. I take 800mg daily, and I

am 30 years old. When I started Gleevec I was a victim of the usual

bone/joint pain that goes along with it. That was fine-none of the

side effects bother me when I consider the alternatives. Anyhow,

about 3 years ago I started having trouble with jaw pain and the

dentist diagnosed TMD (or TMJ). And now, in October, (it started as

I was packing the car for Light the Night) I started having lower

back pain which has consistently gotten worse and had me in the

hospital for close to a week, and I go in for surgery 2 days after

Christmas. I have a grade 3 Spondylolisthesis (L5), which means

that my bottom vertabrea is slipped forward 50-75% and is pinching

the nerves causing severe pain in my back and legs. So, what I am

wondering is if Gleevec can have this type of effect on bones and

joints. I have good strong bones-just ask the poor doctors who have

to do my bone marrow biopsies. And I am only 30. I never used to

have these types of problems. So, could it be Gleevec related and

how bad could it get, or am I just getting old? (Thirty hit me

HARD...) Just curious if anyone has any thoughts on this.

Thanks,

Holly

[Guest guest]

Holy Toledo! I've been having an awful time with jaw pain and kind of a " frozen

jaw " feeling. I wondered what brought that on, and now that you mention it, I,

too, am wondering if it's Gleevec-related.

hollyt0825 wrote:

> Hi everyone! I know I don't post much and its been a long time, but

> I was wondering about something and was wondering if anyone here

> would know anything about this.

> I have been on Gleevec since August 2000. I take 800mg daily, and I

> am 30 years old. When I started Gleevec I was a victim of the usual

> bone/joint pain that goes along with it. That was fine-none of the

> side effects bother me when I consider the alternatives. Anyhow,

> about 3 years ago I started having trouble with jaw pain and the

> dentist diagnosed TMD (or TMJ). And now, in October, (it started as

> I was packing the car for Light the Night) I started having lower

> back pain which has consistently gotten worse and had me in the

> hospital for close to a week, and I go in for surgery 2 days after

> Christmas. I have a grade 3 Spondylolisthesis (L5), which means

> that my bottom vertabrea is slipped forward 50-75% and is pinching

> the nerves causing severe pain in my back and legs. So, what I am

> wondering is if Gleevec can have this type of effect on bones and

> joints. I have good strong bones-just ask the poor doctors who have

> to do my bone marrow biopsies. And I am only 30. I never used to

> have these types of problems. So, could it be Gleevec related and

> how bad could it get, or am I just getting old? (Thirty hit me

> HARD...) Just curious if anyone has any thoughts on this.

> Thanks,

> Holly

>

>

>

>

[Guest guest]

Thanks for the responses and emails. Looks like this might be

something to look into. I still think all the side effects I have

had so far have been well worth it-a pain in the butt at most,

uncomfortable of course. But if this is Gleevec related it would be

good to know. I don't like to automatically assume that every ache

and pain is Gleevec/Leukemia related but I really wonder about this

one. If anyone else has any thoughts on this I would love to hear

them.

Thanks again

Holly

>

> > Hi everyone! I know I don't post much and its been a long time,

but

> > I was wondering about something and was wondering if anyone here

> > would know anything about this.

> > I have been on Gleevec since August 2000. I take 800mg daily,

and I

> > am 30 years old. When I started Gleevec I was a victim of the

usual

> > bone/joint pain that goes along with it. That was fine-none of

the

> > side effects bother me when I consider the alternatives. Anyhow,

> > about 3 years ago I started having trouble with jaw pain and the

> > dentist diagnosed TMD (or TMJ). And now, in October, (it

started as

> > I was packing the car for Light the Night) I started having lower

> > back pain which has consistently gotten worse and had me in the

> > hospital for close to a week, and I go in for surgery 2 days

after

> > Christmas. I have a grade 3 Spondylolisthesis (L5), which means

> > that my bottom vertabrea is slipped forward 50-75% and is

pinching

> > the nerves causing severe pain in my back and legs. So, what I

am

> > wondering is if Gleevec can have this type of effect on bones and

> > joints. I have good strong bones-just ask the poor doctors who

have

> > to do my bone marrow biopsies. And I am only 30. I never used

to

> > have these types of problems. So, could it be Gleevec related

and

> > how bad could it get, or am I just getting old? (Thirty hit me

> > HARD...) Just curious if anyone has any thoughts on this.

> > Thanks,

> > Holly

> >

> >

> >

> >