Re: Prozac & Ginkgo Biloba mixture: new therapy?

[Guest guest]

Very interesting. I would be very reluctant to give prozac... might be willing to try Gingko. I was only able to get to one abstract, have you tried? Do you know who these people are? Some of it just simply sounds too good be true. I am somewhat skeptical due to lack of information and not knowing these people ( anyone can say whatever they want on the net ) I do remember gingko coming up on other list and Ginger and Dr L both saying it was not good for DS, but as the article mentions, the research has kind of turned thinking a bit upside down, so maybe it's just what IS needed? Are you going to give the ginko a try for sure? Let us know what happens. I think I am up for trying something new... haven't added anything since trying bacopa last year. ;-) Müller <mueller-winter@...> wrote: Hello all,what do you think about this?www.curingdownsyndrome.comIt prompted me to order Ginkgo Biloba for (I'll wait with Prozac until I get a thumbs up from the scientists and doctors who are working with it)Just in case anyone's interested: I found a good quality, SCD compatible Ginkgo product (doesn't contain millet or rice flour like many others)at:http://www.vitaminlife.com/product-exec/PNAME/Ginkgo_Biloba_60mg_24___Extract/product_id/14590,Switzerlandwith Saskia-my wife, Nora-Jane, 5yrs. & , 21mo/DS/GERDCarol in IL Mom to seven including , 6 with TOF, AVcanal, GERD, LS, Asthma, subglottal stenosis, chronic constipation ( cured now ) and DS. My problem is not how I look. It's how you see me.

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[Guest guest]

Do you know who these people are? Some of it just simply sounds too good be true.

I am somewhat skeptical due to lack of information and not knowing these people

..

Carol,

The folks in the link gave you are down here in Houston. is on this list. She can better address how she feels GB is working for her son. I know there was another drug she spoke of, but for the life of me can't remember. I'm trying it with Martha, but also giving her the piracetam for the time being. Don't want to lose the "snap" she has, especially with trying to school her and starting new therapies. Once it's in her I'll probably back off the piracetam. We also discussed the serotonin connection, so I'm looking at

l-trytophan and p5p to help with that.

Tina

[Guest guest]

Hello Carol,

you're right: all of a sudden the links are not working anymore. I managed to find most texts elsewhere though - food for thought, I'd say. The paper on Ginkgo Biloba is a PDF, so I couldn't include it in this message, but instead I've uploaded it into the files section. Name: Bilobalide_GABA.

Ginkgo Biloba was found to have more or less the same effect as Picrotoxin (see below), which is VERY amazing.

I asked Dr. Leichtman about what he thinks: he gave me a thumbs up for Ginkgo, so the tide surely has changed in this matter...He's cautious about Prozac, though. Me too, after all our kids can't really be compared to mutant mice!

I ordered Ginkgo from www.vitaminlife.com ("Now Foods" standardized Ginkgo extract caps)

I'll let you know about our experiences with Ginkgo Biloba as soon as enters university :-)

Exp Neurol. 2006 Jul;200(1):256-61. Epub 2006 Apr 19.

Fluoxetine rescues deficient neurogenesis in hippocampus of the Ts65Dn mouse model for Down syndrome. S, Schwalbe J, Stasko MR, Yarowsky PJ, Costa AC.Department of Pharmacology and Exp. Therapeutics, University of land School of Medicine, Baltimore, MD 21201-1509, USA.The Ts65Dn mouse, an adult model of Down syndrome displays behavioral deficits consistent with a dysfunctional hippocampus, similar to that seen with DS. In looking for mechanisms underlying these performance deficits, we have assessed adult neurogenesis in the dentate gyrus of Ts65Dn. Under untreated conditions, Ts65Dn mice (2-5 months old) showed markedly fewer BrdU-labeled cells than euploid animals. Chronic antidepressant treatment for over 3 weeks with the serotonin selective reuptake inhibitor, fluoxetine, increased neurogenesis in the Ts65Dn to comparable levels seen in the euploid by augmenting both proliferation and survival of BrdU-labeled cells in the subgranular layer and granule cell layer of the hippocampus, respectively.http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve & db=PubMed & list_uids=16624293 & dopt=Citation

J Neurosci. 2004 Sep 15;24(37):8153-60.

Hippocampal long-term potentiation suppressed by increased inhibition in the Ts65Dn mouse, a genetic model of Down syndrome.Kleschevnikov AM, Belichenko PV, Villar AJ, Epstein CJ, Malenka RC, Mobley WC.Department of Neurology and Neurological Sciences, and the Institute for Neuroscience, Stanford University Medical School, Stanford University, Stanford, California 94305-5489, USA. akleschevnikov@...Although many genetic disorders are characterized by cognitive failure during development, there is little insight into the neurobiological basis for the abnormalities. Down syndrome (DS), a disorder caused by the presence of three copies of chromosome 21 (trisomy 21), is characterized by impairments in learning and memory attributable to dysfunction of the hippocampus. We explored the cellular basis for these abnormalities in Ts65Dn mice, a genetic model for DS. Although basal synaptic transmission in the dentate gyrus was normal, there was severe impairment of long-term potentiation (LTP) as a result of reduced activation of NMDA receptors. After suppressing inhibition with picrotoxin, a GABA(A) receptor antagonist, NMDA receptor-mediated currents were normalized and induction of LTP was restored. Several lines of evidence suggest that inhibition in the Ts65Dn dentate gyrus was enhanced, at least in part, because of presynaptic abnormalities. These findings raise the possibility that similar changes contribute to abnormalities in learning and memory in people with DS and, perhaps, in other developmental disorders with cognitive failure.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve & db=PubMed & dopt=Abstract & list_uids=15371516

Re: Prozac & Ginkgo Biloba mixture: new therapy?

Very interesting.

I would be very reluctant to give prozac... might be willing to try Gingko.

I was only able to get to one abstract, have you tried?

Do you know who these people are? Some of it just simply sounds too good be true.

I am somewhat skeptical due to lack of information and not knowing these people ( anyone can say whatever they want on the net )

I do remember gingko coming up on other list and Ginger and Dr L both saying it was not good for DS, but as the article mentions, the research has kind of turned thinking a bit upside down, so maybe it's just what IS needed?

Are you going to give the ginko a try for sure? Let us know what happens. I think I am up for trying something new... haven't added anything since trying bacopa last year. ;-) Müller <mueller-winterhispeed (DOT) ch> wrote:

Hello all,what do you think about this?www.curingdownsyndrome.comIt prompted me to order Ginkgo Biloba for (I'll wait with Prozac until I get a thumbs up from the scientists and doctors who are working with it)Just in case anyone's interested: I found a good quality, SCD compatible Ginkgo product (doesn't contain millet or rice flour like many others)at:http://www.vitaminlife.com/product-exec/PNAME/Ginkgo_Biloba_60mg_24___Extract/product_id/14590,Switzerlandwith Saskia-my wife, Nora-Jane, 5yrs. & , 21mo/DS/GERD

Carol in IL

Mom to seven including , 6 with TOF, AVcan al, GERD, LS, Asthma, subglottal stenosis, chronic constipation ( cured now ) and DS.

My problem is not how I look. It's how you see me.

All-new - Fire up a more powerful email and get things done faster.

[Guest guest]

It looks pretty good and interesting . . . but I'll have to look at it further to decide if we'll give it (GB) to my brother or not. I've come across GB before (like when looking up Bacopa - since I believe they are in the same "family).

Qadoshyah

*Got Down Syndrome?

www.gotdownsyndrome.net

From: Down Syndrome Treatment [mailto:Down Syndrome Treatment ] On Behalf Of MüllerSent: Friday, September 01, 2006 7:51 AMDown Syndrome Treatment Subject: Prozac & Ginkgo Biloba mixture: new therapy?

Hello all,what do you think about this?www.curingdownsyndrome.comIt prompted me to order Ginkgo Biloba for (I'll wait with Prozac until I get a thumbs up from the scientists and doctors who are working with it)Just in case anyone's interested: I found a good quality, SCD compatible Ginkgo product (doesn't contain millet or rice flour like many others)at:http://www.vitaminlife.com/product-exec/PNAME/Ginkgo_Biloba_60mg_24___Extract/product_id/14590,Switzerlandwith Saskia-my wife, Nora-Jane, 5yrs. & , 21mo/DS/GERD

[Guest guest]

This is an interesting web site. I am wondering why St. 's Wort couldn't be used instead of Prozac? What do you think Qadoshyah? Please let me know what you think when you have looked this up further.

Sue Mayer

Mom to Sam (5) with Down Syndrome on NACD program

RE: Prozac & Ginkgo Biloba mixture: new therapy?

It looks pretty good and interesting . . . but I'll have to look at it further to decide if we'll give it (GB) to my brother or not. I've come across GB before (like when looking up Bacopa - since I believe they are in the same "family).

Qadoshyah

*Got Down Syndrome?

www.gotdownsyndrome.net

From: Down Syndrome Treatment [mailto:Down Syndrome Treatment ] On Behalf Of MüllerSent: Friday, September 01, 2006 7:51 AMDown Syndrome Treatment Subject: Prozac & Ginkgo Biloba mixture: new therapy?

Hello all,what do you think about this?www.curingdownsyndrome.comIt prompted me to order Ginkgo Biloba for (I'll wait with Prozac until I get a thumbs up from the scientists and doctors who are working with it)Just in case anyone's interested: I found a good quality, SCD compatible Ginkgo product (doesn't contain millet or rice flour like many others)at:http://www.vitaminlife.com/product-exec/PNAME/Ginkgo_Biloba_60mg_24___Extract/product_id/14590,Switzerlandwith Saskia-my wife, Nora-Jane, 5yrs. & , 21mo/DS/GERD

[Guest guest]

Hi Sue,

I plan to look this up further in the next few weeks. We are going to order GB for my brother & start giving it to him. But, I have to look into the Prozac stuff further. I'm really busy right now writing a thesis for school, so it'll be 2-4 weeks until I can get back to looking at this subject. I am very interested in it though, so I'll definently research it out further, Lord willing !

Qadoshyah

*Got Down Syndrome?

www.gotdownsyndrome.net

From: Down Syndrome Treatment [mailto:Down Syndrome Treatment ] On Behalf Of Sue MayerSent: Wednesday, September 06, 2006 5:07 PMDown Syndrome Treatment Subject: Re: Prozac & Ginkgo Biloba mixture: new therapy?

This is an interesting web site. I am wondering why St. 's Wort couldn't be used instead of Prozac? What do you think Qadoshyah? Please let me know what you think when you have looked this up further.

Sue Mayer

Mom to Sam (5) with Down Syndrome on NACD program

RE: Prozac & Ginkgo Biloba mixture: new therapy?

It looks pretty good and interesting . . . but I'll have to look at it further to decide if we'll give it (GB) to my brother or not. I've come across GB before (like when looking up Bacopa - since I believe they are in the same "family).

Qadoshyah

*Got Down Syndrome?

www.gotdownsyndrome.net

From: Down Syndrome Treatment [mailto:Down Syndrome Treatment ] On Behalf Of MüllerSent: Friday, September 01, 2006 7:51 AMDown Syndrome Treatment Subject: Prozac & Ginkgo Biloba mixture: new therapy?

Hello all,what do you think about this?www.curingdownsyndrome.comIt prompted me to order Ginkgo Biloba for (I'll wait with Prozac until I get a thumbs up from the scientists and doctors who are working with it)Just in case anyone's interested: I found a good quality, SCD compatible Ginkgo product (doesn't contain millet or rice flour like many others)at:http://www.vitaminlife.com/product-exec/PNAME/Ginkgo_Biloba_60mg_24___Extract/product_id/14590,Switzerlandwith Saskia-my wife, Nora-Jane, 5yrs. & , 21mo/DS/GERD