RE: Re: [ Oxidative stress in Alzheimer's disease: implications for prevention and therapy.KATHY

[Guest guest]

Anti-oxidants are the main thing to help stop oxidative stress. Blueberries, Tart Cherries, Glutathione, Zinc, Selenium, Vitamin E, C, etc. This is partly why you want to test some of these levels regularly (zn, se, e, etc) to make sure they are not deficient in these *key* anti-oxidants. The antioxidants that we give my brother besides Nutrivene-D are:

Blueberry extract (one ot *the* best anti-oxidants!)

Tart Cherry extract

Carnosine

& soon to add Grape Seed Extract with Resveratrol

Qadoshyah

*Got Down Syndrome?

www.gotdownsyndrome.net

From: Down Syndrome Treatment [mailto:Down Syndrome Treatment ] On Behalf Of and BehnkeSent: Tuesday, July 04, 2006 9:25 AMDown Syndrome Treatment Subject: Re: [ Oxidative stress in Alzheimer's disease: implications for prevention and therapy.KATHY

I have not read all of these yet. I have my husbandprint them at work so I can read when I have "quitetime" but I was wondering does it say what we give ourkids to help stop this Oxidative/carbon dioxideprocess from happening in them.Thanks and Happy 4th --- Kathy Ratkiewicz <Kathy_Rcomcast (DOT) net> wrote:> > Subcell><javascript:AL_get(this,%20'jour',%20'Subcell%20Biochem.');>> Biochem. 2005;38:65-78.> > Related><http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed & cmd=Display & dopt=pu> bmed_pubmed & from_uid=15709473> Articles, Links> <javascript:PopUpMenu2_Set(Menu15709473);> > > > Oxidative stress in Alzheimer's disease:> implications for prevention and> therapy.> > ><http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed & cmd=Search & itool=pu> bmed_Abstract & term=%22Behl+C%22%5BAuthor%5D> Behl C.> > Institute for Physiological Chemistry & > Pathobiochemistry, Faculty of> Medicine, Johannes Gutenberg University, Mainz,> D-55099 Mainz, Germany.> > Oxidative stress is a marker of neurodegeneration> and has been recently> shown to be also involved in the early stages of the> pathogenesis of various> neurodegenerative disorders. In general, all> biomolecules of the cell can be> oxidized and thereby damaged. Consequently, the> concept of neuroprotection> by antioxidants has been developed. In many cases> the direct scavanging of> free radicals have been used as a strategy to> prevent oxidative stress> damage and a variety of physiological and synthetic> antioxidant molecules> have been identified and synthesized including the> female sex homone> estrogen. In Alzheimer's Disease amyloid-beta> protein on its way to brain> deposition can also induce oxidative changes> rendering nerve cells more> vulnerable to additional insults. In addition,> inflammatory mediators are> attracted by amyloid deposits that can further speed> up the generation of an> oxidative micro-environment. Based on recent> clinical data the use of a> combination of various antioxidants might indeed be> effective in preventing> Alzheimer's Disease. Nevertheless, the exact> molecular mechanisms and the> real impact of oxidative stress on the development> and progression of> Alzheimer's Disease as well as of other> neurodegenerative disorders still> needs to be further investigated.> > > >http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed & cmd=Retrieve & dopt=Ab>stract & list_uids=15709473 & query_hl=6 & itool=pubmed_DocSum> > __________________________________________________

[Guest guest]

Here is another article explaining what antioxidants are:

http://www.wisegeek.com/what-are-antioxidants.htm

kathyR

From: Down Syndrome Treatment [mailto:Down Syndrome Treatment ] On Behalf Of Hoppin' Herd of Hares

Sent: Tuesday, July 04, 2006 2:48

PM

Down Syndrome Treatment

Subject: RE:

Re: [ Oxidative stress in Alzheimer's disease:

implications for prevention and therapy.KATHY

Anti-oxidants are the main

thing to help stop oxidative stress. Blueberries, Tart Cherries, Glutathione,

Zinc, Selenium, Vitamin E, C, etc. This is partly why you want to test some of

these levels regularly (zn, se, e, etc) to make sure they are not deficient in

these *key* anti-oxidants. The antioxidants that we give my brother

besides Nutrivene-D are:

Blueberry extract (one ot

*the* best anti-oxidants!)

Tart Cherry extract

Carnosine

& soon to add Grape

Seed Extract with Resveratrol

Qadoshyah

*Got Down

Syndrome?

www.gotdownsyndrome.net

From: Down Syndrome Treatment [mailto:Down Syndrome Treatment ] On Behalf Of and Behnke

Sent: Tuesday, July 04, 2006 9:25

AM

Down Syndrome Treatment

Subject:

Re: [ Oxidative stress in Alzheimer's disease:

implications for prevention and therapy.KATHY

I have not read all

of these yet. I have my husband

print them at work so I can read when I have " quite

time " but I was wondering does it say what we give our

kids to help stop this Oxidative/carbon dioxide

process from happening in them.

Thanks and Happy 4th

--- Kathy Ratkiewicz <Kathy_Rcomcast (DOT) net>

wrote:

>

> Subcell

>

<javascript:AL_get(this,%20'jour',%20'Subcell%20Biochem.');>

> Biochem. 2005;38:65-78.

>

> Related

>

<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed & cmd=Display & dopt=pu

> bmed_pubmed & from_uid=15709473> Articles, Links

> <javascript:PopUpMenu2_Set(Menu15709473);>

>

>

> Oxidative stress in Alzheimer's disease:

> implications for prevention and

> therapy.

>

>

>

<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed & cmd=Search & itool=pu

> bmed_Abstract & term=%22Behl+C%22%5BAuthor%5D>

Behl C.

>

> Institute for Physiological Chemistry &

> Pathobiochemistry, Faculty of

> Medicine, Johannes Gutenberg University,

Mainz,

> D-55099 Mainz, Germany.

>

> Oxidative stress is a marker of neurodegeneration

> and has been recently

> shown to be also involved in the early stages of the

> pathogenesis of various

> neurodegenerative disorders. In general, all

> biomolecules of the cell can be

> oxidized and thereby damaged. Consequently, the

> concept of neuroprotection

> by antioxidants has been developed. In many cases

> the direct scavanging of

> free radicals have been used as a strategy to

> prevent oxidative stress

> damage and a variety of physiological and synthetic

> antioxidant molecules

> have been identified and synthesized including the

> female sex homone

> estrogen. In Alzheimer's Disease amyloid-beta

> protein on its way to brain

> deposition can also induce oxidative changes

> rendering nerve cells more

> vulnerable to additional insults. In addition,

> inflammatory mediators are

> attracted by amyloid deposits that can further speed

> up the generation of an

> oxidative micro-environment. Based on recent

> clinical data the use of a

> combination of various antioxidants might indeed be

> effective in preventing

> Alzheimer's Disease. Nevertheless, the exact

> molecular mechanisms and the

> real impact of oxidative stress on the development

> and progression of

> Alzheimer's Disease as well as of other

> neurodegenerative disorders still

> needs to be further investigated.

>

>

>

>

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed & cmd=Retrieve & dopt=Ab

>

stract & list_uids=15709473 & query_hl=6 & itool=pubmed_DocSum

>

>

..

[Guest guest]

I appreciate it! How do you know how much of those to

give him?

--- Hoppin' Herd of Hares <feargod@...>

wrote:

> Anti-oxidants are the main thing to help stop

> oxidative stress. Blueberries,

> Tart Cherries, Glutathione, Zinc, Selenium, Vitamin

> E, C, etc. This is

> partly why you want to test some of these levels

> regularly (zn, se, e, etc)

> to make sure they are not deficient in these *key*

> anti-oxidants. The

> antioxidants that we give my brother besides

> Nutrivene-D are:

>

> Blueberry extract (one ot *the* best anti-oxidants!)

> Tart Cherry extract

> Carnosine

> & soon to add Grape Seed Extract with Resveratrol

>

> Qadoshyah

> <http://www.geocities.com/gotgenetics/home.html>

> *Got Down Syndrome?

> www.gotdownsyndrome.net

> <http://www.gotdownsyndrome.net/>

> <http://www.geocities.com/dsinfo05/home.html>

>

>

> _____

>

> From: Down Syndrome Treatment

> [mailto:Down Syndrome Treatment ] On

> Behalf Of and

> Behnke

> Sent: Tuesday, July 04, 2006 9:25 AM

> Down Syndrome Treatment

> Subject: Re: [ Oxidative

> stress in Alzheimer's

> disease: implications for prevention and

> therapy.KATHY

>

>

>

> I have not read all of these yet. I have my husband

> print them at work so I can read when I have " quite

> time " but I was wondering does it say what we give

> our

> kids to help stop this Oxidative/carbon dioxide

> process from happening in them.

>

> Thanks and Happy 4th

>

>

> --- Kathy Ratkiewicz <Kathy_Rcomcast (DOT)

> <mailto:Kathy_R%40comcast.net> net>

> wrote:

>

> >

> > Subcell

> >

>

<javascript:AL_get(this,%20'jour',%20'Subcell%20Biochem.');>

> > Biochem. 2005;38:65-78.

> >

> > Related

> >

> <http://www.ncbi.

>

<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed & cmd=Display & dopt=pu

> >

>

nlm.nih.gov/entrez/query.fcgi?db=pubmed & cmd=Display & dopt=pu

> > bmed_pubmed & from_uid=15709473> Articles, Links

> > <javascript:PopUpMenu2_Set(Menu15709473);>

> >

> >

> > Oxidative stress in Alzheimer's disease:

> > implications for prevention and

> > therapy.

> >

> >

> >

> <http://www.ncbi.

>

<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed & cmd=Search & itool=pu

> >

>

nlm.nih.gov/entrez/query.fcgi?db=pubmed & cmd=Search & itool=pu

> > bmed_Abstract & term=%22Behl+C%22%5BAuthor%5D> Behl

> C.

> >

> > Institute for Physiological Chemistry &

> > Pathobiochemistry, Faculty of

> > Medicine, Johannes Gutenberg University, Mainz,

> > D-55099 Mainz, Germany.

> >

> > Oxidative stress is a marker of neurodegeneration

> > and has been recently

> > shown to be also involved in the early stages of

> the

> > pathogenesis of various

> > neurodegenerative disorders. In general, all

> > biomolecules of the cell can be

> > oxidized and thereby damaged. Consequently, the

> > concept of neuroprotection

> > by antioxidants has been developed. In many cases

> > the direct scavanging of

> > free radicals have been used as a strategy to

> > prevent oxidative stress

> > damage and a variety of physiological and

> synthetic

> > antioxidant molecules

> > have been identified and synthesized including the

> > female sex homone

> > estrogen. In Alzheimer's Disease amyloid-beta

> > protein on its way to brain

> > deposition can also induce oxidative changes

> > rendering nerve cells more

> > vulnerable to additional insults. In addition,

> > inflammatory mediators are

> > attracted by amyloid deposits that can further

> speed

> > up the generation of an

> > oxidative micro-environment. Based on recent

> > clinical data the use of a

> > combination of various antioxidants might indeed

> be

> > effective in preventing

> > Alzheimer's Disease. Nevertheless, the exact

> > molecular mechanisms and the

> > real impact of oxidative stress on the development

> > and progression of

> > Alzheimer's Disease as well as of other

> > neurodegenerative disorders still

> > needs to be further investigated.

> >

> >

> >

> >

> http://www.ncbi.

>

<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed & cmd=Retrieve & dopt=A

> b>

>

nlm.nih.gov/entrez/query.fcgi?db=pubmed & cmd=Retrieve & dopt=Ab

> >

>

stract & list_uids=15709473 & query_hl=6 & itool=pubmed_DocSum

> >

> >

>

> __________________________________________________

>

[Guest guest]

The blueberry & tart cherry, since they are a natural source of antioxidants (their just a fruit), we just give him one whole capsule of each. We could give him more, I'm sure, but that is just what we give. We only give them in extracts because he doesn't seem to be able to tolerate the blueberry & tart cherry juices that we have (he has some reflux & I think it is a bit too strong for his stomach). But, he handles the extracts (it's a powder) mixed with his vitamins with no problem.

Carnosine - we give 100mgs. When I was looking at Carnosine, I found a recommended dosage (it was 14mgs per Kg - http://www.smart-drugs.com/ias-carnosine-NAC.htm).

Grape Seed Extract & Resveratrol - haven't figured it all the way out yet on how much to give.

Qadoshyah

*Got Down Syndrome?

www.gotdownsyndrome.net

From: Down Syndrome Treatment [mailto:Down Syndrome Treatment ] On Behalf Of and BehnkeSent: Tuesday, July 04, 2006 12:47 PMDown Syndrome Treatment Subject: RE: Re: [ Oxidative stress in Alzheimer's disease: implications for prevention and therapy.KATHY

I appreciate it! How do you know how much of those togive him?--- Hoppin' Herd of Hares <feargodatruechurch (DOT) info>wrote:> Anti-oxidants are the main thing to help stop> oxidative stress. Blueberries,> Tart Cherries, Glutathione, Zinc, Selenium, Vitamin> E, C, etc. This is> partly why you want to test some of these levels> regularly (zn, se, e, etc)> to make sure they are not deficient in these *key*> anti-oxidants. The> antioxidants that we give my brother besides> Nutrivene-D are:> > Blueberry extract (one ot *the* best anti-oxidants!)> Tart Cherry extract> Carnosine> & soon to add Grape Seed Extract with Resveratrol> > Qadoshyah > <http://www.geocities.com/gotgenetics/home.html> > *Got Down Syndrome?> www.gotdownsyndrome.net> <http://www.gotdownsyndrome.net/>> <http://www.geocities.com/dsinfo05/home.html> > > > _____ > > From: Down Syndrome Treatment > [mailto:Down Syndrome Treatment ] On> Behalf Of and> Behnke> Sent: Tuesday, July 04, 2006 9:25 AM> Down Syndrome Treatment > Subject: Re: [ Oxidative> stress in Alzheimer's> disease: implications for prevention and> therapy.KATHY> > > > I have not read all of these yet. I have my husband> print them at work so I can read when I have "quite> time" but I was wondering does it say what we give> our> kids to help stop this Oxidative/carbon dioxide> process from happening in them.> > Thanks and Happy 4th> > > --- Kathy Ratkiewicz <Kathy_Rcomcast (DOT) > <mailto:Kathy_R%40comcast.net> net>> wrote:> > > > > Subcell> >><javascript:AL_get(this,%20'jour',%20'Subcell%20Biochem.');>> > Biochem. 2005;38:65-78.> > > > Related> >> <http://www.ncbi.><http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed & cmd=Display & dopt=pu> >>nlm.nih.gov/entrez/query.fcgi?db=pubmed & cmd=Display & dopt=pu> > bmed_pubmed & from_uid=15709473> Articles, Links> > <javascript:PopUpMenu2_Set(Menu15709473);> > > > > > > Oxidative stress in Alzheimer's disease:> > implications for prevention and> > therapy.> > > > > >> <http://www.ncbi.><http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed & cmd=Search & itool=pu> >>nlm.nih.gov/entrez/query.fcgi?db=pubmed & cmd=Search & itool=pu> > bmed_Abstract & term=%22Behl+C%22%5BAuthor%5D> Behl> C.> > > > Institute for Physiological Chemistry & > > Pathobiochemistry, Faculty of> > Medicine, Johannes Gutenberg University, Mainz,> > D-55099 Mainz, Germany.> > > > Oxidative stress is a marker of neurodegeneration> > and has been recently> > shown to be also involved in the early stages of> the> > pathogenesis of various> > neurodegenerative disorders. In general, all> > biomolecules of the cell can be> > oxidized and thereby damaged. Consequently, the> > concept of neuroprotection> > by antioxidants has been developed. In many cases> > the direct scavanging of> > free radicals have been used as a strategy to> > prevent oxidative stress> > damage and a variety of physiological and> synthetic> > antioxidant molecules> > have been identified and synthesized including the> > female sex homone> > estrogen. In Alzheimer's Disease amyloid-beta> > protein on its way to brain> > deposition can also induce oxidative changes> > rendering nerve cells more> > vulnerable to additional insults. In addition,> > inflammatory mediators are> > attracted by amyloid deposits that can further> speed> > up the generation of an> > oxidative micro-environment. Based on recent> > clinical data the use of a> > combination of various antioxidants might indeed> be> > effective in preventing> > Alzheimer's Disease. Nevertheless, the exact> > molecular mechanisms and the> > real impact of oxidative stress on the development> > and progression of> > Alzheimer's Disease as well as of other> > neurodegenerative disorders still> > needs to be further investigated.> > > > > > > >> http://www.ncbi.><http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed & cmd=Retrieve & dopt=A> b>>nlm.nih.gov/entrez/query.fcgi?db=pubmed & cmd=Retrieve & dopt=Ab> >>stract & list_uids=15709473 & query_hl=6 & itool=pubmed_DocSum> > > > > > __________________________________________________>