Guest guest Posted March 24, 2008 Report Share Posted March 24, 2008 , The fall in platelets and hemoglobin are not so abrupt that one needs to be particularly worried, but you have crossed that " magic threshold " of 100,000 (or 100) platelets. Given this drop, it is necessary to perform this evaluation in order to assess you needs for treatment. Rick Furman, MD > > I have attached to this email an excert of my last 6 months of blood work > (including charts which makes easier reading). Just in case some members > feel nervous about opening the attachment, I have appended the key numbers > below: > > > > > > > 12/08/2007 > > 11/10/2007 > > 23/11/2007 > > 15/02/2008 > > 30/03/2008 > > > HB > > 14.3 > > 13.2 > > 14.1 > > 12.7 > > 12.3 > > > > > 12/08/2007 > > 11/10/2007 > > 23/11/2007 > > 15/02/2008 > > 30/03/2008 > > > Whites > > 6.3 > > 6.6 > > 7.9 > > 7.8 > > NK > > > > > 12/08/2007 > > 11/10/2007 > > 23/11/2007 > > 15/02/2008 > > 30/03/2008 > > > Platelets > > 118 > > 125 > > 137 > > 104 > > 79 > > > > > 12/08/2007 > > 11/10/2007 > > 23/11/2007 > > 15/02/2008 > > 30/03/2008 > > > Neuts > > 3.7 > > 3.1 > > 3.3 > > 3.3 > > NK > > > > > 12/08/2007 > > 11/10/2007 > > 23/11/2007 > > 15/02/2008 > > 30/03/2008 > > > Lymphs > > 1.8 > > 3.1 > > 4.2 > > 4.1 > > 2.6 > > > > I am now 25 months post Rituxan and Chlorambucil which has served me > extremely well, but symptoms have returned over recent months. My story is > somewhat complicated in that I have found myself without a Haematologist in > recent months until yesterday when I meet my new Haematologist for the first > time. She was very meticulous in her examination of my previous history and > of myself, so I feel quite confident that I can work with her going forward. > She ordered a battery of blood tests, including CD38 and FISH to recheck my > markers before any future treatment. She even called me later in the day to > say that she had taken a look at some of my blood results and she was > concerned about the failing HB and Platelets and in view of this she has > scheduled me for a more blood tests, BMB and CT Scan. She was concerned > that my CLL has transformed into something more aggressive, or ITP, or a > viral activation such as CMV. > > > > Over the last 6 months my health has been a little up and down, muscle and > joint pains in the lower limbs, tiredness and fatigue. > > > > My questions is two fold, (i) do you feel that my Haematologist is just > being cautious in ordering these additional tests and (ii) do my blood > results demonstrate that something serious is going on, other than just a > marrow that's becoming a little compacted and therefore restricting the > production of normal cell lines. > > > > Appreciate any views you may have and maybe Dr Furman might be able to pass > comment. > > > > Regards > > > > > > UK, Bournemouth. Dx May 2000. Age 51. Oral Fludarabine 2002. 4 weeks of > Rituxan June 04 and Jan 05. Oct 05/Feb 06 monthly Rituxan and Chlorambucil. > Trisomy 12, IgVH mutated, ZAP70 -ve, CD38 -ve. > Quote Link to comment Share on other sites More sharing options...
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