Re: After Rituxan - Revlimid - Lon

[Guest guest]

,

Do you have any idea when it will hit the open market? 2009-2010?

AnnSee AOL's top rated recipes and easy ways to stay in shape for winter.

[Guest guest]

Here is a lot of info on this topic...This should help with your

questions

http://www.clltopics.org/Chemo/Revlimid.htm

>

> ,

> Do you have any idea when it will hit the open market? 2009-2010?

>

> Ann

>

>

>

> **************************************See AOL's top rated recipes

> (http://food.aol.com/top-rated-recipes?NCID=aoltop00030000000004)

>

[Guest guest]

,My oncologist said two of his own patients went into complete remission on Revlimid, so there is evidence that it works. Sorry if I gave the impression that it was ineffective overall. Everyone is different. The most important thing is that we let each other know what treatments are being used for various lymphomas. I've gotten several ideas for future treatments from this group.BTW, I'm in that RevAssist program mentioned in the link provided by UKN. Lon Re: After Rituxan - Revlimid - Lon

Lon - there is much hope out there for Revlimid, just want you to know - See AOL's top rated recipes and easy ways to stay in shape for winter.

Be a better friend, newshound, and know-it-all with Mobile. Try it now.

[Guest guest]

It's approved for multiple myeloma now - a few more trial results are needed, I think - you can get it now in a doctor's office, but VERY expensive - See AOL's top rated recipes and easy ways to stay in shape for winter.

[Guest guest]

Lon - not sure what the RevAssist program is - must have missed something - See AOL's top rated recipes and easy ways to stay in shape for winter.

[Guest guest]

Ann,

Revlimid is currently available. It has been approved by the Food and Drug Administration (FDA) for use in multiple myeloma and myelodysplastic syndrome. Once approved, an agent can be used by a physician for any indication. The problem with Revlimid is its expense, which has prompted many insurance companies to deny its use in any indications other than the two approved by the FDA.

Whether or not Revlimid is ever approved for CLL remains to be seen. Celgene will have to file with the FDA and go through an arduous process in order to obtain approval. There is a "middle ground" that might be possible where there could be widespread use and support from the insurance companies without FDA approval, but that is something that only will be known in the future.

The current study investigating Revlimid in CLL that is being undertaken with registration with FDA in mind is on hold due to tumor lysis syndrome occurring in several patients. This study might be a 1-2 years from completion.

I assure all of you that there are many, many other agents available in clinical trials that are looking very promising (Humax-CD20, Enzostuarin, ABT-263), so do not dispair.

Rick Furman

Re: After Rituxan - Revlimid - Lon

> , > Do you have any idea when it will hit the open market? 2009- > 2010? > > Ann > > > > **************************************See AOL's top rated recipes > (http://food.aol.com/top-rated-recipes?NCID=aoltop00030000000004) >

[Guest guest]

Thank you, Dr. Furman for following up on these for

us.

Geraldine

--- " R. Furman " <rrfurman@...>

wrote:

---------------------------------

Ann,

Revlimid is currently available. It has been approved

by the Food and Drug Administration (FDA) for use in

multiple myeloma and myelodysplastic syndrome. Once

approved, an agent can be used by a physician for any

indication. The problem with Revlimid is its expense,

which has prompted many insurance companies to deny

its use in any indications other than the two approved

by the FDA.

Whether or not Revlimid is ever approved for CLL

remains to be seen. Celgene will have to file with

the FDA and go through an arduous process in order to

obtain approval. There is a " middle ground " that

might be possible where there could be widespread use

and support from the insurance companies without FDA

approval, but that is something that only will be

known in the future.

The current study investigating Revlimid in CLL that

is being undertaken with registration with FDA in mind

is on hold due to tumor lysis syndrome occurring in

several patients. This study might be a 1-2 years

from completion.

I assure all of you that there are many, many other

agents available in clinical trials that are looking

very promising (Humax-CD20, Enzostuarin, ABT-263), so

do not dispair.

Rick Furman

Re: After Rituxan - Revlimid - Lon

> ,

> Do you have any idea when it will hit the open

market? 2009-

> 2010?

>

> Ann

>

>

>

> **************************************See AOL's top

rated recipes

>

(http://food.aol.com/top-rated-recipes?NCID=aoltop00030000000004)

>