Guest guest Posted August 31, 2008 Report Share Posted August 31, 2008 Dear Herb, I believe Fludarabine and flavonoids are very different—flavopiridol has been tried as a drug for pts refractory to fludarabine. If I remember the results weren't promising but it tells you they're not the same family. I suggest you look up the drugs online; there's a wealth of info about each and most is surprisingly easy to understand. Have you and your doctor discussed Chlorambucil as a possible alternative to fludarabine? I'd be curious if Chlorambucil and Revlamid or Chlorambucil and Campath have been tried together. Why don't you Google each combination and see what comes up. I didn't have Revlamid but the side-effects are reputedly fewer than with it's predecessor, Thalidomide—which I did take for 15 months. Neutropenia was never a problem. The biggest problem was a stupor-like fatigue, which I understand has been greatly reduced with Revlamid. I got used to it so I'm sure whatever fatigue is associated with Revlamid is manageable. At some point I developed a rash thought to be related to the Thalid and cortisone cream worked. -Ellen Diamond On Aug 31, 2008, at 1:47 PM, Herb Simons wrote: > > As I said in a earlier post a while back I'm still considering a SCT. > My WBC is now 250,000 but other counts are near or at normal. I'm > refractory to flavinoids(?) i.e.. fludurabine, cytuxan. I can go > into a Revlimid trial or take Campath. I had a a bad case of CMV and > neutropenia which put me in the hospital from my first FCR treatment. > And CMV is problem with Campath. I understand neutropenia is a side > effect of both Revlimid and Campath .Revlimid has a lot of > unpleasant side effects as does Campath. Has anyone in the group > had either of these drugs? How bad were the side effects? > > Thanks, > > Herb Simons > -- > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 1, 2008 Report Share Posted September 1, 2008 Hi Herb, My father is currently on his second week of Campath (3x per week for 3 months). We chose this chemo as the prior one, (combo Rituxin, Cytoxin, and Vincristine) did not have any results. I researched the Campath website prior to him going on it and have since watched him get many of the side effects. The biggest benefit is that there is not nearly as much nausea as other chemos.....the downfall is that he had had severe chills and fever post treatment as well as the mouth sores (I believe you refer to it as CMV). Typically, effects only happen the day of treatment...however his oncologist said the effects may lessen as he progresses with the treatment. Hope this info helps a bit. > > > As I said in a earlier post a while back I'm still considering a SCT. > My WBC is now 250,000 but other counts are near or at normal. I'm > refractory to flavinoids(?) i.e.. fludurabine, cytuxan. I can go > into a Revlimid trial or take Campath. I had a a bad case of CMV and > neutropenia which put me in the hospital from my first FCR treatment. > And CMV is problem with Campath. I understand neutropenia is a side > effect of both Revlimid and Campath .Revlimid has a lot of > unpleasant side effects as does Campath. Has anyone in the group > had either of these drugs? How bad were the side effects? > > Thanks, > > Herb Simons > -- > Quote Link to comment Share on other sites More sharing options...
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