Dr. Bubalo, #2

[Guest guest]

Dr. Bubalo, #2

Drug Interactions

* cause reduction of chemotherapeutic effects........

St. 's Wort, garlic, gingko, grape seed, Kava, nutmeg, quercitin

(partial list)

*chemotherapy drugs affected............

includes Gleevec, Taxol, Tamoxifen (partial list, included many

familiar sounding drugs used with BMT, preconditioning and treatment)

**per Dr. Bubalo, problem with St. 's Wort, it speeds up

metabolism of Gleevec and it is not as effective.

____________________

some herbals or supplements increase the effects of selected

chemotherapy drugs

these include:

echinacea, ginseng, goldenseal, grapefruit juice/seed extract,

licorice, milk thistle (fruit and seed), red clover, red yeast,

valerian, wild cherry

____________________

____________________

Effects on Blood Elements

**may lower platelets

**may affect red blood cell production

**may increase early types of blood cells

**may increae the risk of bleeding when used with blood thinning

agents (ie warfarin/Coudadin)

Agents which may reduce platelet numbers (complete list given)

*alpha lipoic acid (IV)

*chromium picolinate

*Gingko biloba (WHO ADR Report)

*kava kava (chronic use)

*L-arginine (IV)

*Lentinan (shiitake mushroom component)

*parsley (massive amount of volatile oil)

*pokeweed

*selenium

*ephedra (6 cases with FDA)......banned substance

Agents which may increase the effects of blood thinners (complete

list given)

*arnica

*bilberry

*Bishop's Weed

*borage seed oil

*bromelian

*chamomile

*clove

*coenzyme Q-10

*danshen

*dexpanthenol

*Devil's Claw

*Dong Quai

*Fenugreek

*feverfew

*fish oils

*garlic

*ginger

*gingko biloba

*ginseng

*green tea

*horse chestnut sweet clover

*IP-6 (inositol 6 hexaphosphate)

*licorice

*meadowsweet

*onion

*papain

*parsley

*passion flower

*quassia

*quinine...........which some of us use for muscle cramps

*red clover

*Reishi mushroom

*St. 's Wort

*sweet clover

*tumeric

*Vit E-containing herbs (ie sunflower seeds)

______________

Agents that may decrease iron absorption

*black cohosh

*chamomile

*feverfew

*hawthorn

*gossypol

*nettle

*plantain

*saw palmetto

*St. 's Wort

*valerian

Take these 2 hours away from any iron supplements

______________

Increase early forms of blood cells (may be undesirable)

*alkylglycerols (shark cartilage and shark liver oil)

*melatonin

__________________

Agents of concern with surgery

**Stop these agents 2 weeks before surgery

echinacea - affects liver function

ephedra (Ma huang) - increased cardiac risk ......now banned

garlic, ginkgo, ginseng - affect blood clotting

St. 's Wort - decreases efficacy of anesthetics

valerian - makes anesthesia unpredictable

resume them when it is OK with your surgeon

_____________________

next installment.....herbal safety issue, regulation of herbal

industry

[Guest guest]

Hi ,

your posts are very informative, but looking over the

lists I cannot figure just what would be good for me.

When I was on Myleran I took Cod liver oil caps every

day. but now with gleevec and very low platlets

(around 35,000) I am not sure just what I should take

as I must be careful of brain bleeds... my other

counts are ok white good but hem a bit low..

not too bad for me though.. I have to go for a flu

shot next week as ordered by Hem Doc and would talk to

my GP about any thing I may take if you suggest

something..

thanks

SkipD

" it is only with the heart one see rightly-- what is

essential is invisible to the eyes "

--- Cogan <ncogan@...> wrote:

>

> Dr. Bubalo, #2

>

> Drug Interactions

> * cause reduction of chemotherapeutic

> effects........

> St. 's Wort, garlic, gingko, grape seed, Kava,

> nutmeg, quercitin

> (partial list)

>

> *chemotherapy drugs affected............

> includes Gleevec, Taxol, Tamoxifen (partial list,

> included many

> familiar sounding drugs used with BMT,

> preconditioning and treatment)

>

> **per Dr. Bubalo, problem with St. 's Wort, it

> speeds up

> metabolism of Gleevec and it is not as effective.

> ____________________

>

> some herbals or supplements increase the effects of

> selected

> chemotherapy drugs

>

> these include:

> echinacea, ginseng, goldenseal, grapefruit

> juice/seed extract,

> licorice, milk thistle (fruit and seed), red clover,

> red yeast,

> valerian, wild cherry

> ____________________

> ____________________

>

> Effects on Blood Elements

> **may lower platelets

> **may affect red blood cell production

> **may increase early types of blood cells

> **may increae the risk of bleeding when used with

> blood thinning

> agents (ie warfarin/Coudadin)

>

> Agents which may reduce platelet numbers (complete

> list given)

> *alpha lipoic acid (IV)

> *chromium picolinate

> *Gingko biloba (WHO ADR Report)

> *kava kava (chronic use)

> *L-arginine (IV)

> *Lentinan (shiitake mushroom component)

> *parsley (massive amount of volatile oil)

> *pokeweed

> *selenium

> *ephedra (6 cases with FDA)......banned substance

>

> Agents which may increase the effects of blood

> thinners (complete

> list given)

> *arnica

> *bilberry

> *Bishop's Weed

> *borage seed oil

> *bromelian

> *chamomile

> *clove

> *coenzyme Q-10

> *danshen

> *dexpanthenol

> *Devil's Claw

> *Dong Quai

> *Fenugreek

> *feverfew

> *fish oils

> *garlic

> *ginger

> *gingko biloba

> *ginseng

> *green tea

> *horse chestnut sweet clover

> *IP-6 (inositol 6 hexaphosphate)

> *licorice

> *meadowsweet

> *onion

> *papain

> *parsley

> *passion flower

> *quassia

> *quinine...........which some of us use for muscle

> cramps

> *red clover

> *Reishi mushroom

> *St. 's Wort

> *sweet clover

> *tumeric

> *Vit E-containing herbs (ie sunflower seeds)

> ______________

>

> Agents that may decrease iron absorption

> *black cohosh

> *chamomile

> *feverfew

> *hawthorn

> *gossypol

> *nettle

> *plantain

> *saw palmetto

> *St. 's Wort

> *valerian

>

> Take these 2 hours away from any iron supplements

> ______________

>

> Increase early forms of blood cells (may be

> undesirable)

>

> *alkylglycerols (shark cartilage and shark liver

> oil)

> *melatonin

> __________________

>

> Agents of concern with surgery

>

> **Stop these agents 2 weeks before surgery

> echinacea - affects liver function

> ephedra (Ma huang) - increased cardiac risk

> ......now banned

> garlic, ginkgo, ginseng - affect blood clotting

> St. 's Wort - decreases efficacy of anesthetics

> valerian - makes anesthesia unpredictable

>

> resume them when it is OK with your surgeon

> _____________________

>

> next installment.....herbal safety issue, regulation

> of herbal

> industry

>

>

>

__________________________________

- PC Magazine Editors' Choice 2005

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