Re: my test result BMB

[Guest guest]

Hello Hassan,

Some of your description is unfamiliar to me. I dont know what you mean by 2

cell lines. Do you know how many cells they counted and how many were positive

for the Philadelphia Chromosome? Did they say you may be in an acute stage?

One thing you can do on your own before your dr makes a decision about a new

treatment is to start taking 800 mg glivec everyday. There's a huge diffference

between 600 mg and 800 mg.

Best wishes,

L

[ ] my test result BMB

hi to all

i am hassan from abadan city in iran .i since glivec from 1999 and take glivec

600 mgl every day

this is my frist test bmb after tak glivec.

this is report of test bmb:two cell lines were obeserved both with abnormal

karyotype.a tranclocation between chromsome 9 and 22 indicating philadelphia

chromosome was seen in both cell lines.however one of the cell lines in addition

to that philadelphia chromosome had another derivative 22.philadelphia chromsome

is acytogenetic eveidence fore cml diagnosis.

the presence of the seconed derrive chromosome 22 may also be a sign of acute

transformation.

so that was my bmb but in pass week and this week my test cbc is not good and

is not fixed mydr is sad and worry they told me i must becarfully and perhaps

they want to chang my treatment now i take 600 mgl glivec every day

i must weating and pray to only god

---------------------------------

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[Guest guest]

At 10:09 AM 7/15/05 -0700, you wrote:

>.a tranclocation between chromsome 9 and 22 indicating philadelphia

>chromosome was seen in both cell lines.however one of the cell lines in

>addition to that philadelphia chromosome had another derivative

>22.philadelphia chromsome is acytogenetic eveidence fore cml diagnosis.

>the presence of the seconed derrive chromosome 22 may also be a sign of

>acute transformation.

>so that was my bmb but in pass week and this week my test cbc is not good

>and is not fixed mydr is sad and worry they told me i must becarfully and

>perhaps they want to chang my treatment now i take 600 mgl glivec every day

>i must weating and pray to only god

Hi Hassan,

What was not good about your CBC test? are your blood counts going up or

something?

I know some other patients that have more than the most common

translocation of chromsome

9 and 22.......involving a 3rd chromosome and they have done fine on Gleevec.

Are you seen at a major cancer center? if not, can you see a cml specialist

somewhere?

I hope your doctor can explain to you exactly what the situation

is.........maybe a higher dose of

Gleevec (800mg) will help your treatment.

Let us know what you find out........and best healing wishes to you.

C.