Impact of CAL-101 on Quality of Life

[Guest guest]

What's been the impact of CAL-101 on your Quality of Life? And how has that

changed over the course of treatment? I'd be grateful if you could also share a

risk profile of your disease at the beginning of treatment with CAL-101.

To provide an objective measure of Quality of Life, I've included the Karnofsky

scale:

100% – normal, no complaints, no signs of disease

90% – capable of normal activity, few symptoms or signs of disease

80% – normal activity with some difficulty, some symptoms or signs

70% – caring for self, not capable of normal activity or work

60% – requiring some help, can take care of most personal requirements

50% – requires help often, requires frequent medical care

40% – disabled, requires special care and help

30% – severely disabled, hospital admission indicated but no risk of death

20% – very ill, urgently requiring admission, requires supportive measures or

treatment

10% – moribund, rapidly progressive fatal disease processes

Mark