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Btk and folliculitis

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Btk has been the most tolerable treatment for Tom. We are

both very excited and thankful for Tom to be on this trial.

The biggest side effect after 10 months on protocol for Tom

are the following:

1. Skin rash that looks just like petechia--Tom's platelets

stay between 100-140. That isn't low enough for petichia,

right?

2. Folliculitis--this is some serious stuff that Tom puts

Bactroban ointment on twice a day and still it is out of

control. His face is covered in lesions on some days, but

his upper thigh area has the really bad ones that now need

to be seen by a dermatologist. Dr. Keating recommended oral

antibiotics.

3. Possible skin cancer on face. Tom has already had

melanoma following treatment with FCR. He is checked at

least every 4 months by his dermatologist. Btk seems to be

activating his skin issues. Is there any research

supporting this?

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