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Excellent Article by Dr. Furman

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I read the paper Prognostic Markers and Stratification of

Chronic Lymphocytic Leukemia (Dr Furman author) which was

quite informative on CLL and markers associated with same.

http://asheducationbook.hematologylibrary.org/cgi/reprint/2010/1/77

I have a question hopefully someone has some experience or

knowledge. I have a deletion at 14q32 (IGHx1) 14/200 and a

doubling time of approximately 9 months.

I have searched and find little information on the 14q32.

Only one article " Frequency of 5'IGH deletion in B-

cell.... " by Quintero- F, Nooraie F, Rao P. does any

one have any more input on the deletion?

Also...do not understand the 5'IGH.

Also, if there is little to no info on 14q32 (and I am

assuming 14q32.33) then what is the significance of the

test? Or do you just get the result when you use the prob

CCND1/IGH.

 

Thanks

Jerry

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