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Use of Flow Cytometry in p53 protein function determination

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Is it a 17p deletion or something else?

Suggests that flow cytometry can quickly and easily be used to detect

dysfunction of the p53 protein.

Determination of the functional status of p53 in CLL cells by flow cytometry was

based on

induction of p53 and p21 protein expression using etoposide and nutlin-3a.

This is a letter in the new Nature Journal ~ 'Blood Cancer "

http://www.nature.com/bcj/journal/v1/n2/full/bcj20113a.html

~chris

CLL CANADA

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