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I have a new hematologist/oncologist while I am in my winter

home in AZ. He is very knowledgeable, practices at a major

center at the University and was highly recommended by

others on the lists. He wanted to do a new flow cytometry at

his facility. My previous ones were done by US Labs and

Sloan Kettering in 10-11/2005 at the time of my diagnosis.

Back in 2005 both labs found that I was CD38 pos. and Sloan

Kettering did a Zap-70 that was neg.

The results in AZ were that I was CD 38 neg. but Zap-70 pos

in 62%. My question to our experts is can someone be CD 38

pos and 5+ yrs later be negative? I am not sure if I have

heard of this in all my reading. Also, I know more and more

experts are not in favor of Zap-70 results due to no

standardization of the test.

I remain indolent and have not had one single illness in the

past 5 yrs, and no symptoms. My WBC remains around 20,000

with other results stable. I am Trisomy 12, 13q del and have

not had mutational testing. Any insights?

R

Dx Atypical CLL 11/05

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