Re: 13q deletion percentages vs. other prognostic factors

[Guest guest]

,

I am not sure about this marker trumping other ones, but

here is link to read more about the following:

http://updates.clltopics.org/3378-is-a-higher-percentage-of-cells-with-13q-delet\

ion-more-dangerous

or http://tinyurl.com/3ls422t

" Conversely, CLL with 13q deletion in <70% of nuclei but

involving the RB1 locus, or CLL carrying 13q deletion in =

70% of nuclei, with or without RB1 deletions, collectively

experienced shorter time-to-treatment. A revised flowchart

for the prognostic FISH assessment of del13q-only CLL,

implying the usage of both 13q probes, is proposed. "

Lou

wrote:

/message/15645