Re: New study shows cll cells proliferate at rate of normal lymphs

[Guest guest]

So can we assume from this that just checking our blood could be a waste of time

and also misleading? It seems that a possible biopsy of a lymph node should be a

routing procedure.

Doug

>

> This is interesting info.

>

http://www.dovepress.com/proliferative-index-and-expression-of-cd38-zap-70-and-c\

d25-in-differen-peer-reviewed-article-PLMI

> or http://tinyurl.com/5ujto2b

>

> Ellen

>

[Guest guest]

The title of this post is inaccurate. This paper deals with proliferation

centres.

The rate of proliferation paper was by Chiorazzi N, Rai KR, Ferrarini M. Chronic

lymphocytic leukemia. N Engl J Med. 2005;352(8):804–815.

A node biopsy, spleen biopsy, bone marrow biopsy or blood lymphocyte counts

offer a 'snap shot' of what is occurring in your CLL progression at one location

in the case of biopsies.

But in order to a get a meaningful picture, you need many 'snap shots' over

time.

Still, the clinical progression indicator that matters is still the lymphocyte

doubling time (LDT)

~chris

CLL CANADA WEBSITE

http://cllcanada.ca