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Drug shortages

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There has been a large increase in drug shortages during

2010 and continuing into 2011, particularly for sterile

injectables so often used in hematological cancers. There

was an FDA presentation made recently to FDA patients reps

such as myself by the very understaffed office (total of 4

persons) that deals with drug shortages. I have listed an

FDA link below to the information provided by this office.

The FDA is legislatively limited in the steps it may take

trying to avoid the impact of drug shortages and

discontinuance. A manufacturer is under no legal obligation

to notify FDA of a drug discontinuance, nor is there a

penalty for not notifying the FDA. Two specific clinical

trials were mentioned which are threatened by drug

shortages. There are professional organizations organizing

and lobbying to add more teeth to the regulations, most

active evidently is the American Society of Health-System

Pharmacists: http://www.ashp.org/shortages

http://www.fda.gov/Drugs/DrugSafety/DrugShortages/default.htm

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