Guest guest Posted July 1, 2011 Report Share Posted July 1, 2011 Can anyone comment on this? Merkel cell polyomavirus quote " MCC patients are known to be at a significantly increased risk to develop chronic lymphocytic leukemia (CLL), which is the most common leukemia of adults in the Western world. In addition, it has been shown that CLL patients have a high risk to develop MCPyV positive MCCs. The detection of MCPyV in 22% of the buffy coats of healthy, thus immunocompetent, individuals reported by Pancaldi and colleagues suggests that MCPyV infects specific blood leukocyte cells in which it remains in latency. These data could provide evidence for a multistep transformation model that might be initiated by accumulating mutations of MCPyV in the context of progressive loss of immune surveillance. " End quote Source:Blood http://bloodjournal.hematologylibrary.org/content/117/26/6975.full Abstract: http://bloodjournal.hematologylibrary.org/content/117/26/7099.abstract Quote Link to comment Share on other sites More sharing options...
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