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Cal-101 for untreated patients?

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It looks increasingly as though CAL-101 only works for a

certain period of time, and then cancer finds a way to grow

as if the drug wasn't there.

I personally feel that CAL-101 might be best used with

Campath. The CAL would shrink the nodes, and the Campath

would kill the CLL cells. Campath is risky because of

infection risk, but CAL-101 by itself doesn't do much to

make a dent in CLL.

There is only a 33% response to CAL-101, and it's best used

when docs have a better handle on how use it.

Why use up the drug when it will probably not do much? Keep

it in reserve until good combinations come along. That's my

opinion.

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