re Question about ataxia-telangiectasia

[Guest guest]

In this paper from the journal Leukemia, you will read about

1/4 of the way down the page that ATM deletions only

occurred in 5 of 22 cases of an 11q deletion. I can testify

that I have 11q (but also 13q) and I've had none of the

problems associated with an ATM deletion, having not needed

tx. for 15 yrs. to date (except a blood transfusion last

Thursday for anemia).

http://www.nature.com/leu/journal/v16/n6/full/2402537a.html

There's another paper that I located some time ago (if

anyone's interested, I'll pull it up) that stated that an

11q deletion is a bad one when it's a single deletion and

also bad in a younger population. Since I'm 66, I think my

11q deletion is meaningless. Also, I've been told by

several people that having a 13q deletion also offers

protection from deleterious effects of an 11q loss.

Ellen

cllcanada wrote:

> I know that ataxia-telangiectasia is a rare inherited disorder

> but is 11q deletion effectively the same? Missing ATM?

>

> Thanks

>

> ~chris