Guest guest Posted January 9, 2007 Report Share Posted January 9, 2007 At 11:03 AM 1/9/07 -0800, you wrote: >My sister has been on Gleevec 400mg for a week now and is complaining of >extreme swelling in her ankles. It is also red. This should be brought to her doctor's attention. IF she had a high white count when she started on Gleevec, then all the cell breakdown (killing of the leukemia cells) could give her increased uric acid and this can cause gout, which can occur in the ankles. If her white count was higher than 20,000 when she started Gleevec, the specialists also put you on allopurinal to get rid of the uric acid. The redness sounds like inflammation....which is why I think she may have gout. C. (retired physical therapist) Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 9, 2007 Report Share Posted January 9, 2007 Thank you so much ! It is so comforting to know that there is always someone to ask! I will suggest to my sister that she contact her doctor. On 1/9/07, Cogan <ncogan@...> wrote: > > At 11:03 AM 1/9/07 -0800, you wrote: > >My sister has been on Gleevec 400mg for a week now and is complaining of > >extreme swelling in her ankles. It is also red. > > This should be brought to her doctor's attention. > IF she had a high white count when she started on Gleevec, then all the > cell breakdown (killing of the leukemia cells) could give her increased > uric acid and this can cause gout, which can occur in the ankles. If her > white count was higher than 20,000 when she started Gleevec, the > specialists also put you on allopurinal to get rid of the uric acid. The > redness sounds like inflammation....which is why I think she may have > gout. > > C. (retired physical therapist) > > > -- Iris Colyn Tel: 778-317-1515 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 9, 2007 Report Share Posted January 9, 2007 I got Gout big time! I was even on Allopurinol for weeks before even starting Gleevec. My WBC at dx was 195. Gout is a horrible thing. > > My sister has been on Gleevec 400mg for a week now and is complaining of > extreme swelling in her ankles. It is also red. > > Is this a normal side effect? What is the best treatment? > > Thanks, > > Iris > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 9, 2007 Report Share Posted January 9, 2007 She is taking something for gout ( Zyloprim " - 300mg) but will call her doctor-it may not be strong enough... Thanks again! On 1/9/07, jmace2000 <jmace2000@...> wrote: > > I got Gout big time! I was even on Allopurinol for weeks before even > starting Gleevec. My WBC at dx was 195. Gout is a horrible thing. > > > > > > My sister has been on Gleevec 400mg for a week now and is complaining > of > > extreme swelling in her ankles. It is also red. > > > > Is this a normal side effect? What is the best treatment? > > > > Thanks, > > > > Iris > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 11, 2007 Report Share Posted January 11, 2007 Iris, Swelling and water retention is a very common side-effect of Gleevec, especially the eyes and legs. I have taken it for over four years and I have much experience. The best way to handle this is with diuretics. It doesnt get rid of all, with me, but the majority. It is difficult for me to walk at times because of the edema. Your sister just has to take it day by day. Just keep in mind that diuretics clears the body of potassium, so a supplement is needed. God bless, Denice Iris Colyn <iris.colyn@...> wrote: My sister has been on Gleevec 400mg for a week now and is complaining of extreme swelling in her ankles. It is also red. Is this a normal side effect? What is the best treatment? Thanks, Iris Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 11, 2007 Report Share Posted January 11, 2007 Denice, Thank you so much for the advice. I will suggest to her that she speak to her doctor and ask for diuretics and perhaps also eat some natural diuretics like celery, Leeks, asparagus, dandelion greens, watermelon etc. Wishing you an edema-less future! Iris On 1/11/07, denice landry <daiseymillertoo@...> wrote: > > Iris, > Swelling and water retention is a very common side-effect of Gleevec, > especially the eyes and legs. I have taken it for over four years and I have > much experience. > The best way to handle this is with diuretics. It doesnt get rid of all, > with me, but the majority. > It is difficult for me to walk at times because of the edema. Your sister > just has to take it day by day. Just keep in mind that diuretics clears the > body of potassium, so a supplement is needed. > > God bless, > Denice > > Iris Colyn <iris.colyn@... <iris.colyn%40gmail.com>> wrote: > My sister has been on Gleevec 400mg for a week now and is complaining of > extreme swelling in her ankles. It is also red. > > Is this a normal side effect? What is the best treatment? > > Thanks, > > Iris > > Quote Link to comment Share on other sites More sharing options...
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