Re: UTI's -treatment with Vagifem (oestradoil) - risks and benefits anyone?

[Guest guest]

Hi Isabel - you can find all the information you need to know

here: http://www.vagifem.com/additional_information.html

Luv - Sheila

GP has put me on this treatment and it seems to

be helping with urine infections but... I have concerns about it's origins (is

it chemical? or produced from some other animal species?).

Also what are the risks for cancer (gp said it's better than 'conventional HRT'

as it's 'local'ie. pessaries. I did read that a vaginal ring (what ever that

is!??) is better than pessaries. I've heard the 'local' argument before from

doctors as I don't buy it!!

Anyone any thoughts, knowledge and experiences?

thanks

Isabel

[Guest guest]

Thanks Sheila, this is helpful. I'd also like to know whether the oestrogen is

chemical or organic and how it is obtained. I know there are unnacceptable (to

me at least) ways in which premarin is produced, ie. exploitation of horses.

>

> Hi Isabel - you can find all the information you need to know here:

> http://www.vagifem.com/additional_information.html

>

[Guest guest]

Also just found this! I've not had a hysterectomy...

HRT and womb cancer risk : Unless you have had a hysterectomy, oestrogen only

HRT can increase your risk of cancer of the womb lining (endometrial cancer).

Your doctor won't give you oestrogen only HRT unless you have had a

hysterectomy. Combined HRT does not increase the risk of endometrial cancer.

Isabel

>

> Hi Isabel - you can find all the information you need to know here:

> http://www.vagifem.com/additional_information.html

>

>

[Guest guest]

Hi Isabel, I use Sandrena gel which I rub on the soft tissue of my inner arms and legs. Avoids the allergy to glue with patches and wastage through the digestive tract. Is Vagifem cream based- otherwise it could be drying which would make the situation worse. I'd worry about contaminating my OH with vaginal use- he doesn't need oestrogen! thyroid treatment From: sheila@...Date: Mon, 10 Jan 2011 13:16:35 +0000Subject: RE: UTI's -treatment with Vagifem (oestradoil) - risks and benefits anyone?

Hi Isabel - you can find all the information you need to know

here: http://www.vagifem.com/additional_information.html

Luv - Sheila

GP has put me on this treatment and it seems to

be helping with urine infections but... I have concerns about it's origins (is

it chemical? or produced from some other animal species?).

Also what are the risks for cancer (gp said it's better than 'conventional HRT'

as it's 'local'ie. pessaries. I did read that a vaginal ring (what ever that

is!??) is better than pessaries. I've heard the 'local' argument before from

doctors as I don't buy it!!

Anyone any thoughts, knowledge and experiences?

thanks

Isabel

[Guest guest]

Yhanks

>

>

> Hi Isabel,

> I use Sandrena gel which I rub on the soft tissue of my inner

arms and legs. Avoids the allergy to glue with patches and

Thanks I'll research Sandrena, I am not happy because according to what

I've read oestrogen alone is not advisable when you still have a womb!! Vagifem

is in pessary form and certainly seems to have resolved the uti's so far,so it's

hard to weigh the pro and cons - the UTIs are horrific and turned to Kidney

infection last time.

thanks for the info.

Is

[Guest guest]

Hi isabel, Serenity is progesterone see http://www.progesterone.co.uk for more info. There is also an American supplier that produces cream with the same name ( copyright fight- unless this is now sorted ) ,but this is different and I didn't like using it so much as it was greasy. > thyroid treatment > From: isabelwilson@...> Date: Tue, 11 Jan 2011 11:28:04 +0000> Subject: Re: UTI's -treatment with Vagifem (oestradoil) - risks and benefits anyone?> > > > > >> > > > > > > > > > > > hello isabel> > > > >I'd also like to know whether the oestrogen is chemical or organic and how it is obtained. I know there are unnacceptable (to me at least) ways in which premarin is produced, ie. exploitation of horses.> > > > from looking at their website i would reckon this is a NON-bioidentical product and i think that means that it is not the same > > Thanks for this Trish, I didn't see your post! I have found out that it is indeed yams and soy..> > I am planning a 'chat' with my GP very soon! > > Serenity cream is mentioned here often, I don't know how that varies in consitiuents from Vagifem but will investigate that too incase that can be a substitute.> Thanks again!> Is> > > > > > ------------------------------------> > TPA is not medically qualified. Consult with a qualified medical practitioner before changing medication.> >

[Guest guest]

Hi ,

...... Serenity is progesterone see http://www.progesterone.co.uk for more info.

There is also an American supplier that produces cream with the same name (

copyright fight- unless this is now sorted )

It is the American company - Health and Science- that has the copyright and was

endorsed by Dr R Lee MD. The Wellsprings company sells Serenity that is not

as pure as the Serenity from Health and Science. The Wellsprings Serenity has

petroleum in it as well as other additives. Wellsprings uses progesterone cream

that is sourced in China.

If you go to the Heath and Science website it will list the ingredients in their

Serenity.

B

[Guest guest]

Hi Isobel,

Regarding Vagifem

1/ I would not be concerned about Soy or Yam.

All bio-identicals are " derived " from one of those sources.

They actually alter the molecules to turn them into bio-identical human

hormones. They are then no longer " Soy " or " Yam " at all.

2/ Why are you prescribed the Vagifem?

It is a VERY low dose of Estradiol 10mcg per application (recommended dosage

10mcg daily for 2 weeks then twice a week thereafter) & inserted vaginally.

It will do little for " systemic " Estradiol levels (it won't bring up blood

levels much if at all). It is in fact a product designed to reduce/eliminate

" local " low Estrogen symptoms such as vaginal dryness, itchiness, painful

intercourse due to lack of lubrication.

In fact I am on another product designed for same purpose called Ovestin (made

by Organon (Ireland) Ltd). It is Estriol rather than Estradiol, is a cream

rather than a tablet, is also low dose 0.5mg Estriol per application (note

Estriol is a much weasker Estrogen than Estradiol), also inserted vaginally

using an applicator & has similar dosage recommendations (nightly for 2-3 weeks,

then 2-3 times a week thereafter).

3/ For systemic Estradiol levels & benefits (skin, hair, bones, etc) I use a

topical Estriol compounded Bio-identical Liposomal Gel & my dose is considirably

higher at 3 mgs per day (note I am Postmeno).

4/ I agree Bio-identical Progesterone is also essential & I wouldn't touch

Progestins with the proverbial barge pole. I used to use Progesterone creams but

have for some time now been using a Progest-E By Kenogen. It is Progesterone in

a Vit E Oil & is absorbed either sublingually & or rubbed on lips & gums. I

import from USA (no rx required) & is in fact much cheaper for me than

Progesterone Creams (in Australia need script & must be compounded).

Ray Peat's Progest E Oil (links & details how to order)

http://forums.realthyroidhelp.com/viewtopic.php?f=6 & t=8783 & p=68907

5/ Serenity UK product as per http://www.progesterone.co.uk/ingredients.htm

Contents: Deionised Water, Aloe Barbadensis Leaf Juice (Aloe Vera), Vegetable

Oil, Glycerin, USA Produced USP Natural Progesterone (2.34%) USA, Isopropyl

Myristate, Glyceryl Stearate SE, Cetyl Alcohol, PEG-20 Methyl Glucose

Sesquistearate, Stearic Acid, Sodium Hyaluronate, Sodium PCA, d-alpha

Tocopherol, Methyl Glucose Sesquistearate, Grapefruit Seed Extract, Xanthan Gum,

Carbomer, GermabenII & #61652;, AMP95. (Merest trace of commonly-used

preservatives added due to the ineffectiveness of natural preservatives).

I don't like all the other ingredients (WHY are they necessary at all?) and

especially the Alcohol & PEG.

5/ Sandrena Gel - rx Estradiol

Comes in either 0.5 or 1mg sachets

http://www.medicines.org.uk/emc/medicine/7692/PIL/Sandrena%C2%AE++0.5mg+and+1.0m\

g++gel/

What Sandrena 0.5 mg gel and Sandrena 1 mg gel contain:

The active substance is estradiol.

There is 0.5 mg (milligrams) or 1.0 mg of estradiol in each sachet.

The other ingredients are

Carbopol 974P, trolamine, propylene glycol, alcohol and purified water.

Unfortunately that too contains PEG & Alcohol

Lethal Lee

>

>

> I found this out regarding Vagifem

> 'The ingredient in Vagifem is Estradiol is hemihydrate this is a bioidentical

hromone synthesized, from a plant chemical extracted from yams and soy'

>

> It's good it's plant source but my next concern is the effect of soy on

thyroid function!!! and this for eveyone's info....

>

> ESTROGENS HAVE BEEN REPORTED TO INCREASE THE RISK OF ENDOMETRIAL CARCINOMA.

>

>

[Guest guest]

>

> Hi Isobel,

>

> Regarding Vagifem

>

> 1/ I would not be concerned about Soy or Yam.

> All bio-identicals are " derived " from one of those sources.

> They actually alter the molecules to turn them into bio-identical human

hormones. They are then no longer " Soy " or " Yam " at all.

>

> 2/ Why are you prescribed the Vagifem?

> It is a VERY low dose of Estradiol 10mcg per application (recommended dosage

10mcg daily for 2 weeks then twice a week thereafter) & inserted vaginally.

>

> Hi Lee, Vagifem prescribed for repeated UTIs. I need to check(although I've

stopped using it now -gives me awful headaches and I'm not happy with the risks)

but I think it's 25mcg.

How did you decided if you need progesterone and/or eostrogen?

I have blood tests as follow:

FSH 8 u/L, Ostradiol 118 pmol and Prolactin 188 mu/L

Would these indicate need for both oestrogen and progesterone?

I tried serenity cream but my periods came back after several months of none!!

I am 56.

Thanks for all of the info.

Isabel