Re: Hello new member here....

[Guest guest]

I

beleive it all started with me using beconase corticosteroid sprays doctor

gave for nasal allergies as a child and i remember as a 13 year old

feeling weak and fatigued, I would get dizzy if i stood up too fast etc etc.

Looking back i can now fit the pieces of the puzzle. Through 15 - 22 i was

fine as i know fine to be - energy good, fanatstic libido, good mood, excellent

mental processing, strength, stamina overall pretty healthy and fit as

would be expacted at a young age. At 22 i got a severe chest inflammation after

an infection and got prescribed prednisone. I tapered down as i was told

but thinking back after this i was never right. I can remember the midday

fatigue, slight depression and brain fog started around that sort of age

which was not so bad back then but i noticed it was present, i also was taking

soya protien powders in large amounts as i am lactose intolerant and felt

i needed extra for going to gym. This is the time my health detriorated. I now

know soya is harmful to thyroid. luckily i stopped soya protien powders after

about a year of taking them. I plodded along with life which got

stressful as time went on and i noticed gradual worsening of symptoms over

the next 5- 6 years. Libido decreased, mood was not as hood, energy was down,

midday i would fall asleep especially after eating, if i had not slept and

awaoke naturally or as fully as atleast 8 hours i would suffer. weekends i was

fine, holidays when i could slep in i was fine, but if i had to cut sleep short

then i was feeling it.

At

28 i got a spot of hives and doc presribed prednisone but only at 5 mg for a

week. Told me i did not need to taper. That week i became like my old self for

the first time in maybe 6 years. Libido was up like i remembered, energy and

mood was good and i felt really good and had forgotten i had felt like this

once, it was a holiday too and i noticed it more and thought maybe its the drug

effects and not natural. Once the week was over i was busy back at work and did

not pay attention to how i felt, but noticed my libido was now lower than

before i took prednisone. I did not know what happened or what to make of it.

at

around 29 i suffered stress and started suffering from insomnia where i

would awake after 3- 4 hours and feel panicky. I became depressed started

stressing over everything and anything, my calm mind had gone and i

started having anxiety attacks. Thinking back even when i was around 24- 26 i

would go to bed all tense and anxious and suffer bouts of depression, only now

depression got real bad so these symptoms were there only not so noticeable, i

would have bouts of anxiety just take me over and repetitive thoughts runa

round in my head constantly and became overly negative. I can count on one hand

when i have had normal sleep over 6- 7 years! I went a whole 5 years barely

sleeping 3- 4 hours and would awake all wired and alert would be so

fatigued midday but had to keep going ebcause of work. This was hell and i

struggled through it with caffiene which would barely keep me going, then at

evenings i could not sleep til late and whenh i did i would awake early all

alert and unable to sleep.

Doctors

could not work out what was wrong and gave me prozac, i came home and was going

to take them but binned them and decided to try alternative medicine, which

hardly helped me. I lie, maybe they did, enough to keep me awake and allow me

to function but still no deep refreshing sleep. Infact i have a case of

heavy metal poisoning due to this which is being dealt with and i will see doc

next week and go for chelation. Anyway my sleep got better with a reduction of

stress but never deep and long like before. i still had poor libido, energy and

mood. I feel unwell and never rested.

I

saw Dr peatfield on the web and was desperate so i gave him a try. He put me on

nutrimeds but i said i did not want to take them and we agreed on Isocort. Just

the one isocort calmed down my anxiety and made me feel normal. My mother is

ill and it helped her too. This was amazing, then it would wear off

slowly but the effect lasted all day. This allowed me to function at work

where i was keeping up barely with struggle.

i

am now up to 8 pellets a day and i can function, however i still have no libido

or very very poor fleeting moments of it and my sleep is still not excellent but

i can function now and have enough energy not to get too fatigued. I noticed my

nose is getting oily again and is sebum production is a good thing? i noticed

my facial skin had become very dry when it used to be oily before. My bodytemp

on a morning will be around 35.5 and pulse will be around 65 - 70 but jumps to

around 80 most days around midday. My bodytemp has not gone up past 36 in

mornings, fluctuates around 35- 5 - 35.8. However around 3:00 it shoots up to

around 36.5 to 36.8. I also notice a tickle in my throat recently and it makes

me cough and when i smile widely and tilt my head back it seems like my

throat is touching against something, like something is touching against my

windpipe. I have suspected lead posioning from takeing herbal stuff, maybe teh

lead swells the thyroid? Maybe i have thyroid issues that need sorting or

maybe i need more isocort to kick start the thyroid, anyone got ideas?. I have

a feeling i may have reverse T3 or s syndrome due to the obscene amount

of stres and mental strain i have been under. I am seeing Dr Peatfield

soon anyway and i will ask, he is a legend and i wish him a long healthy

and happy life so he can keep up the good work. I now wish i can get back to

being normal, whatever that will be for my age, i know normal is

not how i am now, i only remember feeling normal at 20 so i dont know

what to expect now 15 years later.

Thanks

to shelia for creating this resource so that we can regain our health.

Best

regards

Mohammed

From: Sheila

<sheila@...>

thyroid treatment

Sent: Sun, 20 February, 2011 12:07:15

Subject: Possible genetic marker

A

meta-analysis of the associations between common variation in the PDE8B gene

and thyroid hormone parameters; including assessment of longitudinal stability

of associations over time and effect of thyroid hormone replacement.

P, Panicker V, Sayers A, Shields B, Iqbal A, Bremner A, Beilby J, Leedman P, Hattersley A, Vaidya B, Frayling T, J, Tobias JH, Timpson NJ, Walsh JP, Dayan CM.

P ,

Henry Wellcome Labarotories for Integrative Neuroscience and Endocrinology,

University of Bristol, Bristol, United Kingdom.

Abstract

Objective Common variants in

PDE8B are associated with TSH, but apparently without any effect on thyroid

hormone levels which is difficult to explain. Furthermore the stability of the

association has not been examined in longitudinal studies or in patients on levothyroxine.

Design Four cohorts were used (N=2,557) the Busselton Health Study (thyroid

function measured on 2 occasions), DEPTH, EFSOCH (selective cohorts) and WATTS

(individuals on levothyroxine). Methods Meta-analysis to clarify associations

between the rs4704397 SNP in PDE8B on TSH, T3 and T4 levels. Results

Meta-analysis confirmed that genetic variation in PDE8B was associated with TSH

(p=1.64x10-10 0.20 SD/allele, 95%CI 0.142, 0.267) and identified a possible new

association with free T4 (p=0.023, -0.07 SD/allele, 95% CI -0.137, -0.01) no

association was seen with free T3 (p=0.218). The association between PDE8B and

TSH was similar in 1981 (0.14 SD/allele, 95%CI 0.04, 0.238) and 1994 (0.20

SD/allele, 95%CI 0.102, 0.300) and even more consistent between PDE8B and free

T4 in 1981 (-0.068 SD/allele, 95% CI: -0.167, 0.031) and 1994 (-0.07 SD/allele,

95%CI: -0.170, 0.030). No associations were seen between PDE8B and thyroid

hormone parameters in individuals on levothyroxine. Conclusion Common genetic

variation in PDE8B is associated with reciprocal changes in TSH and free T4

levels that are consistent over time and lost in individuals on levothyroxine.

These findings identify a possible genetic marker reflecting variation in

thyroid hormone output that will be of value in epidemiological studies and

provides additional evidence that PDE8B is involved in TSH signaling in the

thyroid.

[Guest guest]

Hello Mohammed, I wonder whether you have low testosterone

and/or low aldosterone. If you have not been tested for these, I would get them

done.

Your low body temperature is a definite indication you have

adrenal problems and you should be monitoring these three times daily according

to Dr Rind's Metabolic Temperature Graph. Check out the following:

Track

Your Temperature: A Quick and Easy Way to Determine Metabolic Health

Recognizing

Adrenal and Thyroid Correction Patterns

How

to Take and Plot Temperatures

Interpreting

Results

Metabolic

Temperature Graphâ„¢: A Roadmap to Metabolic Health

Also,

ask for a FULL thyroid function test to include thyroid antibodies (TPO and

TgAb). Do you have any members of your family with a thyroid or autoimmune

disease. You need to get your free T3 tested to see whether your mainly

inactive thyroxine (T4) is converting to the active thyroid hormone T3.

Ask

your GP also to test your levels of ferritin, vitamin B12, vitamin D3,

magnesium, folate, copper and zinc. Don't be too dismissive of the fact that

you might well have a thyroid problem and believe what you are suffering is

only adrenal related - the two walk hand in hand, as does systemic candidiasis

and mercury poisoning caused through amalgam fillings.

I

sincerely hope that Dr Peatfield can pin-point what is stopping you regaining

full health. I have every confidence in him. I look forward to seeing you again

shortly.

Luv

- Sheila

I

saw Dr peatfield on the web and was desperate so i gave him a try. He put me on

nutrimeds but i said i did not want to take them and we agreed on Isocort. Just

the one isocort calmed down my anxiety and made me feel normal. My mother is

ill and it helped her too. This was amazing, then it would wear off slowly but

the effect lasted all day. This allowed me to function at work where i was

keeping up barely with struggle.

i

am now up to 8 pellets a day and i can function, however i still have no libido

or very very poor fleeting moments of it and my sleep is still not excellent

but i can function now and have enough energy not to get too fatigued. I

noticed my nose is getting oily again and is sebum production is a good thing?

i noticed my facial skin had become very dry when it used to be oily before. My

bodytemp on a morning will be around 35.5 and pulse will be around 65 - 70 but

jumps to around 80 most days around midday. My bodytemp has not gone up past

36 in mornings, fluctuates around 35- 5 - 35.8. However around 3:00 it

shoots up to around 36.5 to 36.8. I also notice a tickle in my throat recently

and it makes me cough and when i smile widely and tilt my head back it

seems like my throat is touching against something, like something is touching

against my windpipe.

[Guest guest]

Shelia, thanks for reply,

Testosterone was pretty normal despite all these troubles and stressors, never checked aldosterone, possibly thyroid is an issue i have a ticking sensation in throat and need to clear my throat and cough. I also have found high blood levels of lead and will be seeing doctor on monday for results to confirm the second test and possibly getting IV chelation.

From: Sheila <sheila@...>thyroid treatment Sent: Sun, 20 February, 2011 17:12:06Subject: RE: Hello new member here....

Hello Mohammed, I wonder whether you have low testosterone and/or low aldosterone. If you have not been tested for these, I would get them done.

Your low body temperature is a definite indication you have adrenal problems and you should be monitoring these three times daily according to Dr Rind's Metabolic Temperature Graph. Check out the following:

Track Your Temperature: A Quick and Easy Way to Determine Metabolic Health

Recognizing Adrenal and Thyroid Correction Patterns

How to Take and Plot Temperatures

Interpreting Results

Metabolic Temperature Graphâ„¢: A Roadmap to Metabolic Health

Also, ask for a FULL thyroid function test to include thyroid antibodies (TPO and TgAb). Do you have any members of your family with a thyroid or autoimmune disease. You need to get your free T3 tested to see whether your mainly inactive thyroxine (T4) is converting to the active thyroid hormone T3.

Ask your GP also to test your levels of ferritin, vitamin B12, vitamin D3, magnesium, folate, copper and zinc. Don't be too dismissive of the fact that you might well have a thyroid problem and believe what you are suffering is only adrenal related - the two walk hand in hand, as does systemic candidiasis and mercury poisoning caused through amalgam fillings.

I sincerely hope that Dr Peatfield can pin-point what is stopping you regaining full health. I have every confidence in him. I look forward to seeing you again shortly.

Luv - Sheila

[Guest guest]

Hello Mohammed and welcome to our forum,

Glad to read that you have found Dr. Peatfield already... he will sort you out ;o)

Your story is sad and many of us can associate with the long but steady decline of health. You probably noticed it more acutely, because you went through it earlier than most people here. When symptoms first hits you around the middle of your life, you think that this is the way it goes.... and our doctors, of course, tell us the same. I was told by my GP for 10 years that all my symptoms were down to the menopause – they were not, I suffered from Hashimoto's .... only nobody (other than Dr. Peatfield) would believe me, not friends, not family.... I was still functioning - how could I possibly be ill ?!

So how can we help? You said you had some questions....? Your clinical symptoms certainly all conform with an underactive thyroid gland, and since you are now taking Isocort on Dr. Peatfield's advice you obviously also suffer adrenal fatigue.

Maybe i have thyroid issues that need sorting or maybe i need more isocort to kick start the thyroid, anyone got ideas?. I have a feeling i may have reverse T3 or s syndrome due to the obscene amount of stres and mental strain i have been under.

Right ... you say `maybe' you have thyroid issues.... I think there is no `maybe' about it and I have no doubt that Dr. Peatfield will confirm that when you see him. But Isocort is not a thyroid medication, it is a low cortisol supplement which is available over the counter. It helps you at present because your own cortisol production is probably low. We need cortisol, but it is also something we have to be very careful when supplementing...

I have suspected lead posioning from takeing herbal stuff, maybe teh lead swells the thyroid? Maybe i have thyroid issues that need sortng or maybe i need more isocort to kick start the thyroid, anyone got ideas?. I have a feeling i may have reverse T3 or s syndrome due to the obscene amount of stres and mental strain i have been under.

Whoah, hold your horses, young man, you are getting carried away here .... The first thing – if you have not done this already - is to order Dr. Peatfield's book "Your thyroid and how to keep it healthy" and to study it from cover to cover.... this will save you a lot of time and unnecessary worry in the long run. Everything you need to know will be explained in there. By the sounds of it you do have adrenal fatigue and you probably are hypothyroid and you may have some other hormonal issues in addition, but there is an order of doing things – first you get diagnosed, then your treat as appropriate – and adrenal treatment has priority over thyroid treatment. Stabilize the adrenals first and foremost, then turn your attention to the thyroid treatment.

Normally I would say at this stage, do the adrenal questionnaire and if you score high, do the adrenal salivary test with Genova... but since you are already taking Isocort (steroids), there is no point at that any more. Not to worry – you already know that you have weak adrenals and that Isocort help you – so just carry on. Dr. Peatfield – when you see him - will advise you on how much for how long. Just to put things straight – Isocort does not kick-start your thyroid ... nothing will. There is no such thing as kick-starting the thyroid gland when it is failing. If you have - or are heading for – hypothyroidism there is only proper treatment with thyroid hormone that will get you back to health; and before you ask, that takes time ...if you have a straight forward case, 8-12 months, if there are complications, it can take longer. But worry not, you should improve all along the way... at least that is the idea. Whether you suffer from rT3, 's syndrome or whatever – the first step is to get you diagnosed, the next step to get you treated.

There are two ways of going about the getting diagnosed bit.... either you ask your GP for blood tests and hope that your figures will be sufficiently in the red, in which case you will be offered treatment – or you get diagnosed by someone like Dr. Peatfield, who doesn't give a stuff about lab results not showing the "desired" results, and he would advise you on how to self treat. In my view it would make sense to first of all go to your GP and ask for a full thyroid test – TSH, FT4, FT3 and TPO & TgAb thyroid antibodies (you probably won't get a full test, but every little helps, as they say)....that will give you (and Dr. Peatfield) some idea of what might be going on. Given the fact that thyroid results only venture into the `red' when the thyroid gland is already about 75% compromised, that might explain why the result may still look "normal" when you feel anything but. It can take years for the thyroid results to reflect how a patient is actually feeling, so don't be too disappointed if your GP tells you all is `normal'.

I could go on and on, there is so much to learn, but do get Dr. P's book straight away and start reading. Many things will become clearer then. And do go and see your GP and ask for a full thyroid panel and the mineral & vitamin check Sheila has mentioned and when you've got the figures, please post them on here (with ref ranges).... golden rule – never accept a verdict of `normal', always ask for copies of the results, so you can be the judge of what is `normal' for you.

With best wishes,

[Guest guest]

Dear ,

Interesting what you said about menopause. According to the "experts" I have been going through mine for at least 6 years and it still isn't over yet! I thought I must hold the record for the longest menopause in the history of womankind, but 10 years beats me by far!

MacGilchrist

From: <christina@...>thyroid treatment Sent: Sun, 20 February, 2011 19:26:46Subject: Re: Hello new member here....

.. I was told by my GP for 10 years that all my symptoms were down to the menopause –

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[Guest guest]

hi Mohammed

sorry if my message seemed a bit short, i think reading it back, it did. ie

saying that normal means absolutely nothing.

I agree with you what you write. Your T results are pretty good i'd say. Free

testosterone works out at a good level too.

I think you are right to consider other homrones like thyroid, adrenals (DHEA

too?). Please advise what you scored on the Hertoghe quiz?

do you have sleep apnea?

chris

>

>

>

> Thanks for the reply.

>

> Here are my latest results and an analysis of this 'sex hormone' situation.

> > >

>