Guest guest Posted February 22, 2007 Report Share Posted February 22, 2007 Hi , This is the first I've heard of this trial or anything like it but I get way behind reading the posts, too. What prompted you to get into the trial? Are you living in Houston? Must be with that kind of schedule. I hopeyou're doing okay. It seems those of us in trials are there because we lost response to Gleevec. I'm doing well on Sprycel. Please keep us informed. I've heard so many people (including docs) say that a vaccine will ultimately be the cure for CML. Love, L. [ ] CMLVAX trial Hi Group, I am hopelessly behind all the posts, but I wanted to check in and let you all know that I entered the CMLVAX trial at MDACC. The vaccine trial requires a leukine injection 2 days before each vaccination. The day the vaccine is injected, another injection of leukine is also given. So far I've had some local tenderness and redness, and a little more fatigue and loss of appetite. Not a big deal. I go to MDACC once every two weeks until the end of April, then once every three weeks, becoming once a month in the summer for the balance of the year. Hope all is well, Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 22, 2007 Report Share Posted February 22, 2007 Hi , I still have my response to Gleevec, but my PCRs still show evidence of residual disease. I've remained in CCR for over 5 years. On this trial I remain on 400 mg Gleevec and the vaccine is added. It's a peptide fusion vaccine. It's offered at MSKCC and OHSU as well as MDACC. I'm in this trial to attempt to reduce or eliminate the residual leukemic load. I am still living in the same place! Right down the street from nne where we had breakfast so many years ago. , the little monkey you met when he was seven, is twelve now, and going to prep school. Time passes so quickly, doesn't it? Glad to hear that you're doing well on Sprycel! Best, > > Hi , > > This is the first I've heard of this trial or anything like it but I get way behind reading the posts, too. What prompted you to get into the trial? Are you living in Houston? Must be with that kind of schedule. I hopeyou're doing okay. It seems those of us in trials are there because we lost response to Gleevec. I'm doing well on Sprycel. > > Please keep us informed. I've heard so many people (including docs) say that a vaccine will ultimately be the cure for CML. > > Love, > > L. > [ ] CMLVAX trial > > > Hi Group, > > I am hopelessly behind all the posts, but I wanted to check in and let > you all know that I entered the CMLVAX trial at MDACC. The vaccine > trial requires a leukine injection 2 days before each vaccination. The > day the vaccine is injected, another injection of leukine is also given. > > So far I've had some local tenderness and redness, and a little more > fatigue and loss of appetite. Not a big deal. I go to MDACC once every > two weeks until the end of April, then once every three weeks, > becoming once a month in the summer for the balance of the year. > > Hope all is well, > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 24, 2007 Report Share Posted February 24, 2007 Yes, time seems to move faster and faster. Thanks for the explanation of the trial. I lost my response to Gleevec less than a year ago and when it starts it goes very fast. It started with one bad FISH which was 4% positive. At that point my doctor started trying to get me into a Sprycel trial. I lost out on the town Univ. trial because either their lab was bad or my numbers were hopping around like grasshoppers! In any case I took 3 BMAsw in 2 months time and was literally right on the edge of the numbers to get in but they turned me down. I then went to University of land on the very last day they were letting people begin the entry process and luckily got in. During that period of time I went from 4% FISH, CCR (0) and 2.1% PCR to 6% FISH, 17 positive bcr abl cells out of 20 and 5% PCR. I just had my third BMA last week so we'll see where I am now. But the second one was excellent. CCR, 0 FISH and 000.32 PCR. My Gleevec response took a long time and then didn't really last that long on 800 mg. So I think people CAN tell if they're going to do well. I'm getting BMAs in my sternum now because my left hip no longer has any juice (may come back) and my right hip was damaged in Connecticut during one or more BMBs. I envy your living in California. I live in Falls Church, VA just 8 fast miles out of Washington. There are things I like and things I don't care for--like the winter weather though it's certainly milder than CT! I remember our breakfast very well and your son wanting to run home while we waited for a table. Hope your husband is doing well and so glad you're watching after those nasty little cells we love to hate. All the best, [ ] CMLVAX trial > > > Hi Group, > > I am hopelessly behind all the posts, but I wanted to check in and let > you all know that I entered the CMLVAX trial at MDACC. The vaccine > trial requires a leukine injection 2 days before each vaccination. The > day the vaccine is injected, another injection of leukine is also given. > > So far I've had some local tenderness and redness, and a little more > fatigue and loss of appetite. Not a big deal. I go to MDACC once every > two weeks until the end of April, then once every three weeks, > becoming once a month in the summer for the balance of the year. > > Hope all is well, > > > > > > > Quote Link to comment Share on other sites More sharing options...
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