Levothyroxine better taken at night!

[Guest guest]

Dear Sheila and everyone,

just thought I would let you know about the results of the first large

randomised trial investigating timing of intake of Levothyroxine tablets.

When taken at bedtime there is a decrease in thyrotropin levels, an increase in

free T4 level and an increase in total T3 level compared to morning intake.

The results appear in last weeks Pharmaceutical Journal and go on to say that

clinicians should inform patients about the possibility of taking Levothyroxine

at bedtime. The British National Formulary states that it should preferably be

taken before breakfast in the morning.

As a pharmacist I will definately be informing my patients about this and I hope

that other pharmacists will too.

Take care all,

Jo