Re: New results help please

[Guest guest]

> Just had these results if anyone can interpret them for me, Thankyou in advance xxxx > TSH 1.84 0.27-4.2> TT3 1.9 1.3- 3.1> FT4 14.9 12-22 > Thyroglobulin antibodies 11.42 0-115> Thyroid peroxidase Abs 9.76 0-33

Hi Debbie,

Both your thyroid antibody results are negative ... which - in conjunction with your TFT - makes it more likely that you currently might suffer from some non-thyroidial endocrine condition which could be responsible for your relatively low FT readings as well as your clinical symptoms.... although this is just my opinion. Thyroid antibodies do go up and down, so a thyroid condition can't be definitely ruled out on the strength of just one set of results, but this is the picture that is showing at this point in time....

Please let us know what the endocrinologist says and what the liver specialist will come up with tomorrow.....

Fingers crossed and good luck,

[Guest guest]

>

> Please let us know what the endocrinologist says and what the liver

> specialist will come up with tomorrow.....

>

> Fingers crossed and good luck,

>

>

Hi again

Endo phoned me yesterday to say that all my results (posted earlier in this tag)

are mid range and so normal. When I asked him about seeing him again he said he

will get back to me ??? Here are the results of my SSt test, which I fully

expected to be fine after Sheila read my Genova saliva test for me and told me

nothing to worry about there.

>

Hi & #65279;Cortisol (Baseline) 331 nmol/L

Cortisol (30minutes) 876 nmol/L

Cortisol (60minutes) 1043 nmol/L

Interpretation Guidelines ~ In normal subjects the followingcriteria should be

fulfilled;1) Basal Cortisol exceeds 200nmol/L 2) Increase above baselineexceeds

200 nmol/L.3) Peak Concentration exceeds 550nmol/L -

I also saw Liver specialist yesterday. My liver results are right back down.

When I asked him why they keep fluctuating he said he didnt know and that even

at the highest they are nothing to worry about. I asked him why I feel so ill

most of the time and he said I dont know. I also told him that I keep having

" SYMPTOMS " of hypoglycemia and he replied that that only happens to people on

diabetic medication .. I told him that I can only tell him how I feel. He has

now suggested a prolonged glucose tolerance test. I have said that I will get

back to him as I thought it better that the Endo does this test.

Thankyou all for your patience and help Debbie xx

[Guest guest]

Hello Debbie,

Endo phoned me yesterday to say that all my results (posted earlier in this tag)are mid range and so normal. When I asked him about seeing him again he said hewill get back to me ???

Here are the results of my SST test:

Cortisol (Baseline) 331 nmol/LCortisol (30minutes) 876 nmol/LCortisol (60minutes) 1043 nmol/LInterpretation Guidelines ~ In normal subjects the following criteria should befulfilled;

1) Basal Cortisol exceeds 200nmol/L

2) Increase above baseline exceeds 200 nmol/L.

3) Peak Concentration exceeds 550nmol/L

Hmmmm.... yes, you fulfilled all of the above criteria – and only too well... and I wonder if this is what your endo meant when he said he would get back to you.

According to wiki http://en.wikipedia.org/wiki/ACTH_stimulation_test (and other interpretations of SST) a "normal" response to injecting ACTH is a doubling from baseline cortisol above 200 nmol/L within 1 hour and the increase of peak concentration must exceed 550 nmol/L (which yours did) - your baseline cortisol was 331 nmol/L and you did not just double but more than triple the figure within the hour. I am not a doctor and can't say if this really means something, but in the wiki link (above) it says:

Interpretation for secondary adrenal insufficiency

ACTH may dramatically stimulate cortisol from the low baseline value encountered in patients suffering from secondary adrenal insufficiency. Stimulation resulting in a greater than 14-fold increase in serum concentration over 30 minutes has been reported, although more typically serum cortisol levels will double or triple from baseline. The lower the baseline cortisol, the more likely it is that the patient's cortisol will increase by a large amount.

But it does say above "from a low baseline value..." and I do not know if your baseline level of 331 would be interpreted as "low". One could argue that low means a baseline below 200 nmol/L. So your SST result might be interpreted as a very `healthy' response to ACTH stimulation – or it might arouse suspicion and necessitate further investigation into your pituitary function.... I really could not say which, but it is odd that your endo said he would `get back to you'. I wonder if he wants to discuss your results with a colleague before committing himself, or if it was just a figure of speech.... the thing with a perfectly "normal" or even low TSH but hypothyroid symptoms is that this is exactly what you'd see with pituitary malfunctioning.

I also saw Liver specialist yesterday. My liver results are right back down. When I asked him why they keep fluctuating he said he didnt know and that evenat the highest they are nothing to worry about. I asked him why I feel so illmost of the time and he said I dont know...

Strange that the liver enzymes should all be back in the normal range so quickly. I have no idea either why they might fluctuate so much. But the doc is right in re-assuring you that your liver enzyme elevations were not critical. In someone with liver disease you would see those figures rocket into the many-hundreds. It still is odd though that your figures should yo-yo. My guess is that whatever it is with you, it must be some kind of endocrine malfunction...

.. I also told him that I keep having"SYMPTOMS" of hypoglycemia and he replied that that only happens to people ondiabetic medication ..

Hmmmm – I disagree with that statement. Hypoglycemia can result from all sorts - diabetic medication or diseases yes - but also from hormone or enzyme deficiencies (which includes hypothyroidism) or tumours. It might be worth looking closer at those symptoms in my view. I hope your endo will get back to you....

With best wishes,

[Guest guest]

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> Hello Debbie,

>

> >>

>

> Hmmmm.... yes, you fulfilled all of the above criteria – and only

> too well... and I wonder if this is what your endo meant when he said he

> would get back to you.

>

Thanks

When the Endo said he would get back to me he was going to check if all the

tests he'd asked for were back, but I have not heard from him. in his mind he is

quite clear that all tests are normal.

My liver tests have gone up NOV, DEC,JAN, down FEB, UP MARCH, DOWN APRIL, all

scans clear ...

Your comments have really made me think and I have booked an appointment next

Sunday with Dr Peatfield. I feel sure he will help

Love Debbie