RE: Copper & Zinc Testing

[Guest guest]

I would send a letter to both your GP and endocrinologist asking

for the following tests to be done and cite the references to show the reason

why you are needing these tests, that show the association between low levels

and the symptoms of hypothyroidism.

Low

iron/ferritin:

Iron deficiency is shown to significantly reduce T4 to T3 conversion, increase

reverse T3 levels, and block the thermogenic (metabolism boosting) properties

of thyroid hormone (1-4). Thus, iron deficiency, as indicated by an iron

saturation below 25 or a ferritin below 70, will result in diminished

intracellular T3 levels. Additionally, T4 should not be considered adequate

thyroid replacement if iron deficiency is present (1-4)).

1.

Dillman E, Gale C, Green W, et al. Hypothermia in iron

deficiency due to altered triiodithyroidine metabolism. Regulatory, Integrative

and Comparative Physiology 1980;239(5):377-R381.

2.

SM, PE, Lukaski HC. In vitro hepatic

thyroid hormone deiodination in iron-deficient rats: effect of dietary fat.

Life Sci 1993;53(8):603-9.

3.

Zimmermann MB, Köhrle J. The Impact of Iron and Selenium

Deficiencies on Iodine and Thyroid Metabolism: Biochemistry and Relevance to

Public Health. Thyroid 2002;12(10): 867-78.

4.

Beard J, tobin B, Green W. Evidence for Thyroid Hormone

Deficiency in Iron-Deficient Anemic Rats. J. Nutr. 1989;119:772-778.

Low vitamin B12: http://www.ncbi.nlm.nih.gov/pubmed/18655403

Low vitamin D3: http://www.eje-online.org/cgi/content/abstract/113/3/329

and http://www.goodhormonehealth.com/VitaminD.pdf

Low magnesium: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC292768/pdf/jcinvest00264-0105.pdf

Low folate: http://www.clinchem.org/cgi/content/full/47/9/1738

and http://www.liebertonline.com/doi/abs/10.1089/thy.1999.9.1163

Low 

copper/zinc:http://www.istanbul.edu.tr/ffdbiyo/current4/07%20Iham%20AM%C4%B0R.pdf

and http://articles.webraydian.com/article1648-Role_of_Zinc_and_Copper_in_Effective_Thyroid_Function.html

From: thyroid treatment

[mailto:thyroid treatment ] On Behalf Of fatiguedmummy

Sent: 28 March 2011 18:07

thyroid treatment

Subject: Copper & Zinc Testing

Hi there,

I wanted to get my copper & zinc levels checked as of the relationship with

thyroid hormone manufacture & performance. I've tried both my NHS Endo

& NHS doctor & it's a no go so I'd like to get it done privately.

Although I will be able to get the blood drawn by my NHS doctor.

Does anyone know where I can send off for a kit to get these tested? I've

inquired at Genova Diagnostics & they can only offer a more sophisticated

test which tests 7 toxic elements (antimony, arsenic, cadmium, lead, mercury,

thallium, tin) & 8 nutritional elements (chromium, copper, magnesium,

manganese, potassium, selenium, vanadium, zinc). The cost for this test is

£166.

Does anyone know of another option?

Thanks,

Kerry x