Guest guest Posted March 7, 2011 Report Share Posted March 7, 2011 Hi all, PUBMED= evaluation of usefulness of a sensitive immunoradiometric assay for thyroid stimulating hormone as a first-line thryoid function test in an unselected patient population. ericsson ub, femlund p, thorell jl.scand j clin invest 1987 may;47(3):215-21.A new sensitive immunoraddiometric assay for serum thyroid stimulating hormone (TSH)was applied to 1627 consecutive patients from four large clinics at malmo general hospital, in whom a thyroid function disorder was suspected. the final diagnoses were taken from the patients` charts at a follow-up 1-2 years after the primary evaluation. if only those patients without thyroid disease were used as a reference population, the 5th percentile was 0.8mlu/l.when this cutoff limit was applied to the unselected patient population, the TSH assay had a high sensitivity for the diagnosis of hyperthyroidism((96%)a lower specificity (64%) and a low predictive value (10%). therefore, in the majotity of patients (72%) the sensitive TSH assay CANNOT BE USED ALONE TO DEFINE THYROID FUNCTION.this is for hyperthyroidism so could also apply for hypothyroidism.???so much for the sensitivity of blood tests. regards angel. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 7, 2011 Report Share Posted March 7, 2011 hi sheila/all, here is the link to pubmed-http://www.ncbi.nlm.nih.gov/pubmed/3589485ANGEL. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 8, 2011 Report Share Posted March 8, 2011 Thanks so much Angel. Definitely worth keeping and sending to doctors who insist that TSH is the ONLY test required. Luv - Sheila hi sheila/all, here is the link to pubmed- http://www.ncbi.nlm.nih.gov/pubmed/3589485 ANGEL. Quote Link to comment Share on other sites More sharing options...
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