Guest guest Posted April 28, 2011 Report Share Posted April 28, 2011 Hi Louse My mum has been to the doctors to get the test that you suggested and here are the results, also I have got her an adrenale test and we have got the courier to pick it up today so she should have her results sometime next week that I will also post to you when they come back. Serum Vitamin B12 level (XE2pf) = 393 ng/L (187.0 - 883.0) Vitamin B12 should be right up there at the top of the reference range. Did your GP suggest she supplement this. If not, go to your health food shop and get her Solgar sublingual B12 1000 mcgs to take daily. Because her B12 is so low, she could start off by taking 2000mcgs daily Serum folate leve (42U5.) = 5.8 ng/mL (1.8 - 18.3) Serum folate should be at least above the middle of the reference range so this is far too low. Supplement with taking 5mgs Folic Acid, again, available at your local health food shop. Serium free triiodothyronine level (XaERq) = 4.01 pmol/L (3.6 - 6.5) This is a very narrow range, but her level should be in the upper third of the reference range, so at 4.01, this is too low. Serum free T4 level (XaERr) = 17.0 pmol/L (9.0 - 19.1)This is quite high and with the lowish fT3 shows that she is iprobably not converting the thyroxine (which is mainly inactive) to the active thyroid hormone T3 which every cell in the body and brain needs to make them function. Serum TSH level(XaELV) = 2.8mu/L (0.35 - 4.94) Hmm! This should be around 1.0 so not looking good. Obviously the pituitary is aware that not enough thyroid hormone is in the body and telling the thyroid to start secreting more and this is the reason the TSH is rising. Do you have any previous TSH blood testing results to see what her level was before? Serum Magnesium level (XM0m2) = 0.99 mmol/L (0.7 - 1.0) This is fine and not a problem. Please can you read the results and tell me if you think she is low in something to make her shaky, some days she is fine and then after 2 days she is terrible most of the day. The doctor has put her on a stronger anxiety tablet as he thinks it is nerves but she is not a nervours person at all. There we go again, if the doctor doesn't know what the problem is, more often than not he will resort to doling out antidepressants. Is it possible at all that you could get your Mum to see Dr Peatfield as I am sure you will find that when her 24 hour salivary adrenal test results are returned, it will show she is suffering with adrenal fatigue. As you know, doctors in the NHS refuse to recognise that such a condition exists, so if her results show this, you will have to persuade your Mum to treat this herself, but all the information you need is in our FILES section. Luv - Sheila Thank you Louise xx Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 28, 2011 Report Share Posted April 28, 2011 Hi Sheila Thank you so much for putting our minds at rest. Do you think because she is low in a few things that is could make her shake and feel unwell??? When she went to the doctors, the nurse said in 8 years she has never tested for B12 and never heard of it, I cannot believe this. Do you think we could take these results to the doctor so he can give her B12 injections every 6 weeks like my friend has or should we stick to the health food shop supplement. We are going to the health food shop this morning to get the things we need. I will ring the doctors this morning to check what her previous reading was in the TSH and let you know later today. Also I will make her an appointment with Dr field at the Yorkshire Clinic in June if you still have spaces. Love Louise xx Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 28, 2011 Report Share Posted April 28, 2011 Hi , the tremors could be her adrenals and she may have a conversion problem as well.?? as her T3 may be a bit low. T4 seems to be ok but someone else may be able to tell you more. angel. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 28, 2011 Report Share Posted April 28, 2011 Do you think because she is low in a few things that is could make her shake and feel unwell??? This could be the case, but you need to know which of the associated conditions is causing this problem which you will find by a process of elimination. When she went to the doctors, the nurse said in 8 years she has never tested for B12 and never heard of it, I cannot believe this. Quite appalling! Do you think we could take these results to the doctor so he can give her B12 injections every 6 weeks like my friend has or should we stick to the health food shop supplement. Yes, and if he tries to tell you there is no association between low B12 and hypothyroidism, point him to the following paper(s):Low iron/ferritin: Iron deficiency is shown to significantly reduce T4 to T3 conversion, increase reverse T3 levels, and block the thermogenic (metabolism boosting) properties of thyroid hormone (1-4). Thus, iron deficiency, as indicated by an iron saturation below 25 or a ferritin below 70, will result in diminished intracellular T3 levels. Additionally, T4 should not be considered adequate thyroid replacement if iron deficiency is present (1-4)). 1. Dillman E, Gale C, Green W, et al. Hypothermia in iron deficiency due to altered triiodithyroidine metabolism. Regulatory, Integrative and Comparative Physiology 1980;239(5):377-R381. 2. SM, PE, Lukaski HC. In vitro hepatic thyroid hormone deiodination in iron-deficient rats: effect of dietary fat. Life Sci 1993;53(8):603-9. 3. Zimmermann MB, Köhrle J. The Impact of Iron and Selenium Deficiencies on Iodine and Thyroid Metabolism: Biochemistry and Relevance to Public Health. Thyroid 2002;12(10): 867-78. 4. Beard J, tobin B, Green W. Evidence for Thyroid Hormone Deficiency in Iron-Deficient Anemic Rats. J. Nutr. 1989;119:772-778. Low vitamin B12: http://www.ncbi.nlm.nih.gov/pubmed/18655403 Low vitamin D3: http://www.eje-online.org/cgi/content/abstract/113/3/329 and http://www.goodhormonehealth.com/VitaminD.pdf Low magnesium: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC292768/pdf/jcinvest00264-0105.pdf Low folate: http://www.clinchem.org/cgi/content/full/47/9/1738 and http://www.liebertonline.com/doi/abs/10.1089/thy.1999.9.1163 Low copper/zinc:http://www.istanbul.edu.tr/ffdbiyo/current4/07%20Iham%20AM%C4%B0R.pdf and http://articles.webraydian.com/article1648-Role_of_Zinc_and_Copper_in_Effective_Thyroid_Function.html Ferritin levels for women need to be between 70 and 90 (for men around between 150 and 170). Vitamin B12 needs to be at the top of the range. D3 levels need to be about 50. Magnesium levels need to be at the top of the range, it's one thing that gets missed a great deal. Also I will make her an appointment with Dr field at the Yorkshire Clinic in June if you still have spaces. You need to call me on 01535 636 014 so we can make a convenient appointment for you. If I am not in, leave a message on my phone with your telephone number and I will call you back Love Louise xx 1 of 1 File(s) MINERALS AND VIT. TESTING.doc Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 5, 2011 Report Share Posted May 5, 2011 Hi Sheila Have just got my mums Adrenal Stress Test back and wondered if you could help in reading the results so we can under stand them. Her total daily Cortisol is in the outside rage box of 10.3. It says underneath the range should be 21 - 41 nmol/L Sample 1 is 3.1 (should be between 12 - 22) Sample 2 is 3.1 (should be between 5.0 - 9.0) Sample 3 is 2.9 (should be between 3.0 - 7.0) Sample 4 is 1.2 (should be between 1.0 - 3.0) DHEA Level (what ever these are) Sample 2 (am) is in the inside range box of 0.16 (should be between 0.10 - 0.50) Sample 3 (pm) is in the inside range of 0.17 (should be between 0.4 - 2.0) DHEA: Cortisol Ratio is in the inside range of 1.60 Then it says in the adrenal stress stage box:- Adrenal Fatigue - non-adapted response. This generally indicated falling levels of both cortisol and DHEA from excessive stimulation/secretion over long period of time. It can also reflect the effects of exogenous use of DHEA in adrenal exhaustion states after severl months of DHEA supplementation. DEVIATIONS FROM THE NORMAL CORTISOL RHYTHM The morning cortisol level is below the normal range. Morning cortisol may be a good indication of peak adrenal gland fuction since they represent peak cyclic activity. Low Morning cortisol levels suggest a degree of adrenal hypofunction. The noon cortisol level is below the normal range. Noon cortisol levels may be a good indication of adaptive adrenal gland function since they represent the adrenal gland resonce to the demands of the first few hours of the day. Low noon cortisol suggests a degree of adrenal hypofunction with decreased adaptive adaptive response. A low afternoon cortisol is suggestive of suboptimal adrenal functioning. DEVITIONS IN DHEA PRODUCTION None seen. Sheila could this be why mum is shaky 1st thing in a morning and then not feel much better till after tea some days. Thank you so much Louise x Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 6, 2011 Report Share Posted May 6, 2011 A TSH of 2.8 is not normal, it should be around 1.0. She should have had her free T3 tested and also tested to see whether she has antibodies to her thyroid, especially if there are other members of her family with a thyroid or autoimmune disease. The state of her adrenals does not affect the thyroid function tests particularly, but if the mainly inactive thyroxine (T4) is not converting to the active T3, this might be because cortisol is needed to help with the conversion and conversion would be improved after taking supplements. Is she taking Selenium 200mcgs to help with conversion. This is why we are always asking people to post the reference range for each of the tests done. We can't really tell where her levels lie (i.e. bottom, middle or top) of the range without them. Mostly, people take Nutri Adrenal Extra until their adrenals are fully boosted, this could be a few weeks, a few months, a couple of years depending on how long she has been suffering with low adrenal reserve. We are all different. They are full of vitamins though so will do her the power of good in other ways. She should certainly improve after starting these tablets, we would not suggest members taking them otherwise. I think having a TSH of 2.8 when taking thyroid hormone replacement is a very good reason to ask the GP to give her a trial of an increased dose. Luv - Sheila Thanks Shiela On my mums test 3 weeks ago her Serum Free T4 level was 17.0 and her Serum THS level was 2.8. Is this normal if her Adrenal gland not working properly? Also will it get better with having them tablets you suggested for her Adrenal and will she be on these for life. So aasking the doctor to up her thyroxine wont do anygood really? Louise x Quote Link to comment Share on other sites More sharing options...
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