Gleevec Side Effects

January 24, 2007

It is imparative to take Gleevec on a full stomach and drink plenty of water.

Too often we (including myself at one time) take our meds and disregard the

instructions. You can take Gleevec on a full stomach but what works for me is to

take it in the evenings after my last meal of the night. This way, I follow

directions and if I become nauseated (which I have not in several years) I can

drink water and ly down which potentially gets me to fall asleep. Water is the

key to combat side affects for it cleanses your system and the Gleevec that's

needed has most likely been absorbed already.

Please, follow the directions and modify only when necessary.

rakraaet <skipper3@...> wrote:

, my grandmother has been losing her appetite, along with weight

since she has been taking Gleevec. She has been taking Phenergen for

nausea lately and she has gained a few pounds back.

> > My eyes stay extremely swollen all day long. I also CANNOT eat.

I weight

> > 95lbs and I have to make myself eat. I was wondering if anyone

else is

> > experiencing these side effects and if they go away over time?

Any

> > responses would be appreciated.

> >

> >'

>

> HI '

>

> Often the side effects get less over time, so maybe knowing this is

> helpful. You might try putting a mild cold pack on your eyes (they

make

> some gel masks) or try moist tea bags (chamomile is good). About

the

> eating....do you mean you cannot eat because of nausea or is it

lack of

> appetite? both can happen with Gleevec. Discuss this with your

doctor, or

> your MDACC physician's assistant......sometimes a medication can

help.

> Otherwise, get calories in however you can...like one of the

supplement

> drinks or protein drinks. I have had periods of lack of appetite

and just

> ate comfort foods, even if they were not the most healthy choices.

> Hopefully this will lessen for you. Gleevec is a great drug for

what used

> to be a very bad disease to have......so keeping it all in

perspective can

> also be helpful. Good luck to you,

>

> C.

> dx 8.5 years ago

>

Remember to smile at people, someone may see you and return the favor!

Keyon

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February 3, 2007

Hi '

Sorry you are not feeling well. I have the same deal with eating. Gleevec can

give you kind of low level nausea etc that makes eating not too attractive. May

I suggest what I do? Include a high protein milkshake with your daily intake.

Can get a cheap blender, some protein powder from a health food store and then

add milk, ice cream, crushed ice, friut - whatever tastes good to you. Again try

to add at least 20g of protein via the powder. Can make this taste really good

and cost per serving is just pennies. Might take a multi viatmin daily also.

Personally I have my biggest meal at night and preceed this with a glass of red

wine. Tastes good and stimulates the appetite. See your doctor about some

diurectics to minimixe the eye puffiness. Will help, but unfortunately, probably

not make it go away altogether.

Good Luck

Rick

renee grissom <reneeg8894@...> wrote:

Hello Everyone,

My name is ' , I am 38 years old and I was diagnosed with CML in December

2006. I am new to all of this and I have so many questions. I was accepted at

MDACC and my dr. put me on Gleevec 400mg. I am having a few side effects from

the drug. My eyes stay extremely swollen all day long. I also CANNOT eat. I

weight 95lbs and I have to make myself eat. I was wondering if anyone else is

experiencing these side effects and if they go away over time? Any responses

would be appreciated.

'

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March 7, 2007

Does anyone know of Gastrointestinal side effects of Gleevec such as increased

levels of flattulence?

March 8, 2007

Hi ,

I have had the same problems with Gleevec.

I would suggest that you ask your Dr. about Sandostatin.

It is made by the same people who make Gleevec and comes in 2 types,

long lasting and daily. Both have to be injected, the long lasting by

a Dr. or nurse and the daily you can do your self.

This worked extremely well for me, I was to stop taking the Gleevec

and let nature take its course because I had no quality of life and so

didn't think that quantity was a good trade off.

Hope this helps.

Regards,

Terry

>

> I think I have every known GI problem related to Gleevec. I have been

> hospitalized numerous times for dehydration associated with the side

effects of

> Gleevec and severe Gastritis. The answer is yes. For me, I have

also had/have

> nausea, vomiting. ongoing diarrhea, upset stomach, loose stools. I

also

> have an incredible gurgley stomach about 30-4 minutes after taking

my Gleevec.

> Due to these side effects as well as the intense muscle and bone

aches I get

> after taking it, I take my Gleevec with a evening snack before bed

so that I

> can sleep through the worse of the effects. You have to play

around with it

> and see what works best for you.

>

> Hope that helps in some way-

>

> - 34

> CML 5/13/05

> Gleevec 800 mg

> Wife and mother of 3 (11,8,6)

> ************************************** AOL now

offers free

> email to everyone. Find out more about what's free from AOL at

> http://www.aol.com.

>

March 8, 2007

Definately!!

fischer <efrem_fischer@...> wrote: Does anyone know of

Gastrointestinal side effects of Gleevec such as increased levels of

flattulence?

March 8, 2007

Gurgley is on . I have a personal post maybe a good thing .I had herpes

pry-er to dxt after a year and half on Gleevec had one very mild outbreak.I

would average about every 4 months.Life always has trade off,s Tn age 65

dxt 05

Re: [ ] Gleevec Side Effects

I think I have every known GI problem related to Gleevec. I have been

hospitalized numerous times for dehydration associated with the side effects of

Gleevec and severe Gastritis. The answer is yes. For me, I have also had/have

nausea, vomiting. ongoing diarrhea, upset stomach, loose stools. I also

have an incredible gurgley stomach about 30-4 minutes after taking my Gleevec.

Due to these side effects as well as the intense muscle and bone aches I get

after taking it, I take my Gleevec with a evening snack before bed so that I

can sleep through the worse of the effects. You have to play around with it

and see what works best for you.

Hope that helps in some way-

- 34

CML 5/13/05

Gleevec 800 mg

Wife and mother of 3 (11,8,6)

********* ********* ********* ********* ** AOL now offers free

email to everyone. Find out more about what's free from AOL at

http://www.aol. com.

March 11, 2007

Try some immodium (non-prescription) or if that doesn't work, Lomotil

(prescription) I use the Lomotil and it seems to help.

fischer <efrem_fischer@...> wrote: Does anyone know of

Gastrointestinal side effects of Gleevec such as increased levels of

flattulence?

March 11, 2007

It's very important to get good work-up as I sufferered with nausua, stomach

cramps, vomiting, etc. for the first 5 months I was on Gleevec. My Onc and PCP

thought it was side effects however when I spiked 101 fever, found out it was

diverticulitis. After being hospitalized with strong antibiotic tune-up I feel

better than I ever have. The lesson is that sometimes its too convenient to

blame side effects when there's something else going on not related to Gleevec

or CML.

Margaret

Rick Olds <utfin93@...> wrote:

Try some immodium (non-prescription) or if that doesn't work, Lomotil

(prescription) I use the Lomotil and it seems to help.

fischer <efrem_fischer@...> wrote: Does anyone know of Gastrointestinal

side effects of Gleevec such as increased levels of flattulence?

March 12, 2007

That's a very good point Margaret. We often just assume that what we

are experiencing is a side effect, when in fact it can be something

completely unrelated. I think doctors have a tendency to dismiss

many of our complaints thinking the same thing which is unfortunate.

Take care,

Tracey

--- In , Margaret Peake <mpraymond@...>

wrote:

>

> It's very important to get good work-up as I sufferered with

nausua, stomach cramps, vomiting, etc. for the first 5 months I was

on Gleevec. My Onc and PCP thought it was side effects however when I

spiked 101 fever, found out it was diverticulitis. After being

hospitalized with strong antibiotic tune-up I feel better than I ever

have. The lesson is that sometimes its too convenient to blame side

effects when there's something else going on not related to Gleevec

or CML.

>

> Margaret

>

March 12, 2007

HI MARARET

YOUR RIGHT ABOUT THAT,READ YOUR OWN BODY, & THE DR. ONLY KNOWS WHAT YOU TELL HIM

ABOUT YOURSELF,THEN HE CAN TREAT THE PROUBLEM,I HAVE A GREAT DR. THIS TIME.

PEGGY

Re: [ ] Gleevec Side Effects

It's very important to get good work-up as I sufferered with nausua, stomach

cramps, vomiting, etc. for the first 5 months I was on Gleevec. My Onc and PCP

thought it was side effects however when I spiked 101 fever, found out it was

diverticulitis. After being hospitalized with strong antibiotic tune-up I feel

better than I ever have. The lesson is that sometimes its too convenient to

blame side effects when there's something else going on not related to Gleevec

or CML.

Margaret

Rick Olds <utfin93@...> wrote:

Try some immodium (non-prescription) or if that doesn't work, Lomotil

(prescription) I use the Lomotil and it seems to help.

fischer <efrem_fischer@...> wrote: Does anyone know of Gastrointestinal

side effects of Gleevec such as increased levels of flattulence?

March 12, 2007

I'm on protonix,It seem to work good,Thanks for Input

Peggy

Re: [ ] Gleevec Side Effects

Try some immodium (non-prescription) or if that doesn't work, Lomotil

(prescription) I use the Lomotil and it seems to help.

fischer <efrem_fischer@...> wrote: Does anyone know of Gastrointestinal

side effects of Gleevec such as increased levels of flattulence?

March 12, 2007

I found out you have to remind them of other thing that you have

experienced,they have so many patients and so devoted and caring

Peggy

Re: [ ] Gleevec Side Effects

That's a very good point Margaret. We often just assume that what we

are experiencing is a side effect, when in fact it can be something

completely unrelated. I think doctors have a tendency to dismiss

many of our complaints thinking the same thing which is unfortunate.

Take care,

Tracey

>

> It's very important to get good work-up as I sufferered with

nausua, stomach cramps, vomiting, etc. for the first 5 months I was

on Gleevec. My Onc and PCP thought it was side effects however when I

spiked 101 fever, found out it was diverticulitis. After being

hospitalized with strong antibiotic tune-up I feel better than I ever

have. The lesson is that sometimes its too convenient to blame side

effects when there's something else going on not related to Gleevec

or CML.

>

> Margaret

>

March 12, 2007

I spoke to my doctor this morning. She told me to get anything that has the

ingredient, simetidin. She recommended gaviscon or mylanta gas.

Has anyone used those?

peggy irwin <quinbare@...> wrote:

I'm on protonix,It seem to work good,Thanks for Input

Peggy

Re: [ ] Gleevec Side Effects

Try some immodium (non-prescription) or if that doesn't work, Lomotil

(prescription) I use the Lomotil and it seems to help.

fischer <efrem_fischer@...> wrote: Does anyone know of Gastrointestinal

side effects of Gleevec such as increased levels of flattulence?

March 12, 2007

I've never heard of simetidin but I have heard of simethicone being

helpful for gas.

There's a product called " Gas X " that is made just for flatulence and

it has simethicone in it. I've tried it a few times and found it to be

helpful.

Take care,

Tracey

>

> I spoke to my doctor this morning. She told me to get anything that

has the ingredient, simetidin. She recommended gaviscon or mylanta gas.

>

> Has anyone used those?

>

March 13, 2007

HI

I have lots of gas now that gleevec is quitting on me,I use gas x and it

works,I'm waiting to get sprycel now, Your dr. will find what works for you,hang

in there with us.

Peggy

Re: [ ] Gleevec Side Effects

I've never heard of simetidin but I have heard of simethicone being

helpful for gas.

There's a product called " Gas X " that is made just for flatulence and

it has simethicone in it. I've tried it a few times and found it to be

helpful.

Take care,

Tracey

>

> I spoke to my doctor this morning. She told me to get anything that

has the ingredient, simetidin. She recommended gaviscon or mylanta gas.

>

> Has anyone used those?

>

April 11, 2007

I had experienced same problem of severe Gastritis due to Gleevec and same side

effects. I noticed if I take my 400 mg with big meal I don't feel the same

symptoms. I try now to walk after I take the medicine, which gave me some

relief.

I hope that help

T

dxd 1/03

Gleevec 400mg

PCRU 2/07

--------- Re: [ ] Gleevec Side Effects