RE: Bone and Joint Stiffness

[Guest guest]

Hello-

Sorry to hear about your diagnosis. I have the same thing in my joints. I

would consult with your doctor but I can let you know what I do to relieve my

symptoms. I am on Gleevec 800 mg and have intense muscle aches and bone

pain.

On days when its really not tolerable I use Ibuprofen 600 mg as well as I

soak in a hot bath. It seems to work well for me. I have used Lidoderm

patches from my doctor but they work best on a specific area and when your

whole

leg hurts, it's really not useful.

Sometimes in the first 2-3 months as your Gleevec is hammering away at the

cells in your marrow, things can really be uncomfortable. It should reduce as

your counts go back to a normal range and your marrow settles down. The

shock of the Gleevec in the beginning can be pretty intense. Just know that it

is a good sign that you are having the muscle and bone pain as it is said to

show that the Gleevec is working. That is what I was told at least.

Hang in there. Listen to your body and rest when you need to rest. Stay

warm and don't push yourself too hard. There is an adjustment period to go

through. Take it day by day.

- 34

CML 5/13/05

Gleevec 800 mg

Wife and mother of 3 (11,8,6)

3 log reduction

<BR><BR><BR>**************************************<BR> AOL now offers free

email to everyone. Find out more about what's free from AOL at

http://www.aol.com.

[Guest guest]

I too have joint pain, mostly in my hands. I Have CML since 6/06. I am on 400

mgs of Gleevec, am in Zavie's 0 club and hope I stay there after my

cytogenetic blood test on tuesday. My doctor told me to take calcium which I do

but not

every day. Since I am taking it every day the I don't have the pain as much

or as often. I will be 74 in April. I thought the pain was arthritic but it is

strictly a side affect .

Ask your doctor for his advice.

Ceil

Bronx, NY<BR><BR><BR>**************************************<BR> AOL now offers

free email to

[Guest guest]

Hi Efrem,

Bone and joint pain are common Gleevec side effects. If the pain is

bearable, give it some more time. Side effects do lessen with time.

Zavie

Zavie (age 68)

67 Shoreham Avenue

Ottawa, Canada, dxd AUG/99

INF OCT/99 to FEB/00, CHF

No meds FEB/00 to JAN/01

Gleevec since MAR/27/01 (400 mg)

CCR SEP/01. #102 in Zero Club

PCRU 5/02 at RVH

2.8 log reduction Sep/05

3.0 log reduction Jan/06

e-mail: zmiller@...

Tel: 613-726-1117

Fax: 309-296-0807

Cell: 613-202-0204

ID: zaviem

[ ] Bone and Joint Stiffness

I was diagnosed in January 2007 with CML and have been on 400 mg Gleevec for

the past month and a half.

Lately, I have been experiencinf stiffness in the joints of my hands,

fingers, and toes.

Has anyone experieced this ?

Efrem

Teaneck

[Guest guest]

Hi I,ll put my 2 cents I was given300 mg allopurinol,it's for gout My enc said

while I was killing off the bad w cell's gas and joint pain will happen worked

for me not much pain That was DEC 23 05 .No joint pain almost back to normal

only 3% cancer left should be in that o place about June. Tn

________________________________________________________________________________\

____

We won't tell. Get more on shows you hate to love

(and love to hate): TV's Guilty Pleasures list.

http://tv./collections/265