Thyroid Hormones 'ratio' ~ affects brain function

[Guest guest]

http://dx.doi.org/10.1016/j.neuropharm.2010.12.013

[...Thus, our data demonstrate that T3 and T4 selectively affect GABAergic phasic and tonic neurotransmission. Since THs concentrations can be regulated at the level of the synapses these data suggest that the network activity of the whole brain could be differently modulated depending on the relative amount of these two hormones. Keywords: Thryoid hormones; GABAergic neurotransmission; Neuronal cultures; sIPSCs; Tonic currents; Non genomic effects of thyroid hormones ...]]

Thyroid hormones modulate GABAA receptor-mediated currents in hippocampal neurons