Re: Reference ranges Calcium B12 Folate (brought over from Chat group) [1 Attachment]

[Guest guest]

Thanks for replying Sheila.

My daughter 18 months after TT did have her TFT's done not long ago and TSH just under 1 and T4 had risen to 20. HGB 14.3 and normal HCT with Ferritin still at 8. Intolerant to Ferrous Sulphate.

My TFT's were

TSH <0.1 T4 18 Nov Dec Jan levels haven't changed apart from T4 rising to 19 and back down.

TSH>19.3 T4 13 February Thyrogen for Tg tests undetectable good results but I felt off not ill off.

TSH <0.1 T4 16 Dropped back to undetectable quickly after thyrogen. Took 6 months last year.

TSH >0.5 T4 11 Last weeks results...

Hence my contact with the Endo on Friday. I'll order the Solgar online Sheila.

Many Thanks

Jaki

Facial numbness tingling in fingers and burning, restless feet could be an indication of low B12, and yes, unfortunately, the endocrinologists needs to go back to school to learn that B12 needs to be AT THE TOP of the reference range. Yours is FAR too low and if this was me, I would start a course of sublingual B12 (Solgar is excellent) taking 1000mcgs daily. You might find you do better to start straight off on 2000mcgs until your B12 level starts to build up.

Also, folate is too low (see attached document where you can see where specific minerals and vitamins levels should be in the reference range. Calcium is below the bottom of the reference range. Has your daughter been given a full thyroid function test

Luv - Sheila

Having been symptomatic with facial numbness tingling in fingers with burning restless feet for some months and generally not feeling myself. BP has gone from being low/ normal to High etc. Have been suspicious that calcium and B12 were deficient for sometime.

So Tuesday I requested bloods tests and Thursday I got the results which I'm now querying. Where are the best levels within ref ranges are for Calcium, B12 and Folate. Middle or top of the range? And why? Below are recent results highlighted.

On Friday Folic Acid and Adcal D3 was prescribed by Endo...he didn't think B12 was that low. Thoughts are to phone GP today to discuss B12 which I think is in the low/ normal of the range.

Calcium..2.20, 2.18, 2.13 ref range (2.15-2.65) This has been falling for sometime.

B12.. 553, 378ref range (150-900) First result was Dec took a course of B12 in April??

Serum Folate... 2.8 ref range (3.2-13.0)

[Guest guest]

Solgar Vitamin B12 1000 mcg Nuggets - 250 nuggets by Solgar

Sheila I'm Just making sure this is right product before I order...Jaki.

Hence my contact with the Endo on Friday. I'll order the Solgar online Sheila.

Many Thanks

Jaki

Facial numbness tingling in fingers and burning, restless feet could be an indication of low B12, and yes, unfortunately, the endocrinologists needs to go back to school to learn that B12 needs to be AT THE TOP of the reference range. Yours is FAR too low and if this was me, I would start a course of sublingual B12 (Solgar is excellent) taking 1000mcgs daily. You might find you do better to start straight off on 2000mcgs until your B12 level starts to build up.

Also, folate is too low (see attached document where you can see where specific minerals and vitamins levels should be in the reference range. Calcium is below the bottom of the reference range. Has your daughter been given a full thyroid function test

Luv - Sheila

Having been symptomatic with facial numbness tingling in fingers with burning restless feet for some months and generally not feeling myself. BP has gone from being low/ normal to High etc. Have been suspicious that calcium and B12 were deficient for sometime.

So Tuesday I requested bloods tests and Thursday I got the results which I'm now querying. Where are the best levels within ref ranges are for Calcium, B12 and Folate. Middle or top of the range? And why? Below are recent results highlighted.

On Friday Folic Acid and Adcal D3 was prescribed by Endo...he didn't think B12 was that low. Thoughts are to phone GP today to discuss B12 which I think is in the low/ normal of the range.

Calcium..2.20, 2.18, 2.13 ref range (2.15-2.65) This has been falling for sometime.

B12.. 553, 378ref range (150-900) First result was Dec took a course of B12 in April??

Serum Folate... 2.8 ref range (3.2-13.0)

[Guest guest]

If I can comment here. I agree with what has been said. Unfortunately I cannt open the document for some reason my computer wont accept it, so I cant see or comment on the attachment or its content.

What I would like to just make a comment on is the calcium. Your blood test shows a serum calcium level. This; just as with thyroid hormone; is very different to tissue calcium.

Commonly with hypothyroidism there are high levels of tissue calcium whilst there can be low levels of both serum and bone calcium at the same time. So what is wrong with that?

Calcium is necessary we all know for the good health of bones and teeth where it is stored and further for good cell function and neurological function. Indeed that is where calcium and all our other body minerals are stored in our bones and teeth; the bones are a giant mineral store/pantry.

Calcium and our bone matrix is not static though calcium moves in and out of the bones and teeth. Why? Well because we need it to be also extracellular; that is outside our cells. We need it in balance with magnesium which is inside our cells. The process happens like this:-

In a rhythmic timing like the beat of a drum, the magnesium allows the calcium into the cell where an electrical charge is caused and then the magnesium pushes the calcium out of the cell. In a rhythmic timing again the magnesium allows the calcium into the cell where an electrical charge is caused and then the magnesium pushes the calcium out of the cell...and so on and so forth.

For various reasons it is common for calcium TISSUE levels to be high and magnesium levels to be low in hypothyroids. Why does this matter?

If magnesium is depleted then we do not have adequate magnesium intracellularly or inside the cells. When this is the case calcium is able to get inside our cells; whereby normally under the command and control of magnesium would then be pushed out, but now has free access to stay inside the cells; this is not normal. This is not good for healthy functioning cells. With calcium having free access inside our cells the electrical charges it set s up still occur HOWEVER; they occur in a chaotic manner there is no rhythm and the electrical charges are less forceful without rhythm and disorganised, happening out of rhythm causes disruption inside the cells to occur.

Further this disrupts other processes inside the cells. The sodium pump where sodium and potassium have a positive and negative charge allowing nutrients such as glucose and amino acids etc., in and out of the cell, is disrupted. the body tries to compensate and robs magnesium from the adrenal glands to balance the the calcium at the cellular level. Eventually the magnesium levels in the adrenal glands are also depleted causing further dysfunction in the adrenals and their consequential symptoms too. remember dysfunction in the adrenals will further impact on thyroid gland function and the effect of thyroid hormone at the cellular level; in a negative way.

One test you may not have thought about is a hair analysis. This gives us a strong indicator in respect of what are minerals are doing at the tissue level.

If you take calcium supplements in the current situation you will likely be adding to your body's problems. Infact it is more likely you will need magnesium supplements. Taking magnesium citrate supplements at night will start to bring about a balance between these two giant minerals in our body and the calcium will be pushed to places where it should be rather than hanging around causing chaos where it shouldnt be.

Hair analysis is around £50 (I use trace minerals at mineral check - on the internet) You get a detailed report in 2-3weeks of them receiving your sample. (I have no connection with the company). They will also recommend dietary changes and supplements which will benefit your situation.

Magnesium is an amazing mineral it carries out well over 350 enzymatic processes etc throughout the body. FYI: If you are admitted to hospital with either head injury/stroke etc of heart attack best practice would be to give I.V. infusions of magnesium. the heart muscle must have plentifull supply of magnesium to work effectively. Can you imagine if your heart muscle cells are not pumpin in rhythm? Further the same with the brain magnesium is essential for those electrical charges to occur.

One of the things you mentioned was restless feet and I wonder how much of this is associated with magnesium depletion, since the chaos I described above due to its depletion can cause these restless muscular feelings in feet and legs.....other muscle too such as the heart, since magnesium is actually found stored in both bones and teeth but unlike calcium is also in muscle tissue. Depletion in muscle tissue allows for these odd occurrences.

If you are not taking supplements to support your adrenal glands then may I suggest you think about doing so.

B12 again is commonly depleted with long term hypothyroidism. This is due to the poor functioning of the parietal cells in the stomach. These cells are responsible for releasing hydrochloric acid or stomach acid into the stomach when food is taken. When the parietal cells release hydrochloric acid or HCL this stimulates them to also release intrinsic factor. Intrinsic factor MUST be released before B12 can be absorbed from your food.

Due to the nature of hypothyroidism this process is slowed down as with most other processes in the body. As a consequence of slow production of HCL there is little Intrinsic factor and little or no B12 is absorbed thus leading to B12 depletion and even pernicious anaemia.

We require very little B12 to function normally and further it is one of the vitamins we stores but unusually we store it for up to 5-7 years without effect. But once that store is depleted our body function suffers and particularly the myelin sheath around our nerves. So pins and needles and numbness are some of the many sympotms displayed with B12 deficiency. If the levels are so low you would need injections if not then sublingual supplement should be fine but this is better than taking tablets and depending on gastric absorption for the reasons mentioned above.

however, it is worth increasing your levels of HCL and this can also be done with supplementation. If you dont increase the HCL not only does it affect absorption of B12 but all other nutrients from your food, and of course all of those supplements you take will not be fully or properly absorbed either; further it is required to break down proteins into amino acids and the acid is required to stimulate the pancreas to secrete its alkaline juices/enzymes into the small intestine fo further digestion to occur.

The other thing which is common in hypothyroids is to suffer yeast infection and low stomach acid enables yeasts to proliferate. You need adequate acid in your stomach to prevent invasion of those nasties we may take in with our food. HCL is available through trace minerals (hair analysis people). You take it with your first couple of mouthfulls of food to give the same effect as your body would in normal circumstances release it in the presence of food intake take with every meal.

Best of luck

Sally xx

Facial numbness tingling in fingers and burning, restless feet could be an indication of low B12, and yes, unfortunately, the endocrinologists needs to go back to school to learn that B12 needs to be AT THE TOP of the reference range. Yours is FAR too low and if this was me, I would start a course of sublingual B12 (Solgar is excellent) taking 1000mcgs daily. You might find you do better to start straight off on 2000mcgs until your B12 level starts to build up.

Also, folate is too low (see attached document where you can see where specific minerals and vitamins levels should be in the reference range. Calcium is below the bottom of the reference range. Has your daughter been given a full thyroid function test

Luv - Sheila

Having been symptomatic with facial numbness tingling in fingers with burning restless feet for some months and generally not feeling myself. BP has gone from being low/ normal to High etc. Have been suspicious that calcium and B12 were deficient for sometime.

So Tuesday I requested bloods tests and Thursday I got the results which I'm now querying. Where are the best levels within ref ranges are for Calcium, B12 and Folate. Middle or top of the range? And why? Below are recent results highlighted.

On Friday Folic Acid and Adcal D3 was prescribed by Endo...he didn't think B12 was that low. Thoughts are to phone GP today to discuss B12 which I think is in the low/ normal of the range.

Calcium..2.20, 2.18, 2.13 ref range (2.15-2.65) This has been falling for sometime.

B12.. 553, 378 ref range (150-900) First result was Dec took a course of B12 in April??

Serum Folate... 2.8 ref range (3.2-13.0)