scientists play catch up

[Guest guest]

An interesting article from wellness resources.http://www.wellnessresources.com/health/articles/scientists_play_catch_up_trying_to_understand_thyroid_problems/

Lilian

[Guest guest]

Great article.....but if medical advisors read what Broda wrote years

ago, they'd be up to snuff on all this stuff...all this research just sits in

piles of dust, unread.

Broda believed all illness started with the malfunctioning Thyroid (lack of

thyroid meds)

Back then, people didn't have as many adrenal problems as we do today. The

stress level was a bit lower. I believe all illness starts with the adrenals and

from there we move to the thyroid.

Cheers,

JOT

[Guest guest]

Study

Title:

Hashimoto's

Thyroiditis Affects Symptom Load and Quality of Life Unrelated to

Hypothyroidism: A Prospective Case–Control Study in Women Undergoing

Thyroidectomy for Benign Goiter

Study

Abstract:

Background: Hashimoto’s thyroiditis (HT) is a common

disease, and is the most prevalent cause of hypothyroidism. Symptoms and

diseases associated with HT are considered to be caused by hypothyroidism. We

hypothesized that higher antithyroperoxidase (anti-TPO) antibody levels would

be associated with an increased symptom load and a decreased quality of life in

a female euthyroid patient collective.

Methods: In a prospective cohort study 426 consecutive

euthyroid female patients undergoing thyroid surgery for benign thyroid disease

were included. Main outcome measures were preoperative anti-TPO levels, a

symptom questionnaire and the SF-36 questionnaire, and lymphocytic infiltration

of the thyroid tissue as evaluated by histology.

Results: Histology revealed HT in 28/426 (6.6%) subjects.

To maximize the sum of the predictive values, a cut-off point for anti-TPO of

121.0 IU/mL

was calculated (sensitivity 93.3% [95% confidence interval: 77.9%–99.0%];

specificity 94.7% [95% confidence interval: 92.0%–96.7%]) to predict the

presence of histological signs of HT. The mean number of reported symptoms was

significantly higher in patients with anti-TPO levels >121.0 IU/mL

than in the other group (6.7 ± 2.5

vs. 4.1 ± 2.8;

p < 0.001).

There were no differences in preoperative thyroid-stimulating hormone levels

(1.7 ± 1.3

vs. 1.5 ± 1.4 μU/mL,

respectively; p = 0.155).

Chronic fatigue, dry hair, chronic irritability, chronic nervousness, a history

of breast cancer and early miscarriage, and lower quality-of-life levels were significantly

associated with anti-TPO levels exceeding the cut-off point (p < 0.05).

Conclusions: Women with HT suffer from a high symptom

load. Hypothyroidism is only a contributing factor to the development of

associated conditions.

From press release:

Hashimoto’s thyroiditis (HT), an inflammatory disorder of

the thyroid, is the most common cause of hypothyroidism, but a study has

suggested that even when thyroid function is normal, HT may increase symptoms

and decrease quality of life, as described in an article in Thyroid, a

peer-reviewed journal published by Ann Liebert, Inc.

Hashimoto’s thyroiditis most commonly affects middle-aged

women and is associated with an array of symptoms that include chronic fatigue,

dry hair, chronic irritability, difficulty concentrating, constipation, and

chronic nervousness. Affected patients tend to report decreased quality of

life. HT is an autoimmune disorder in which the body produces an antibody that

attacks the thyroid gland resulting in inflammation, and often decreased

thyroid function (hypothyroidism).

Johannes Ott and colleagues from Kaiserin beth

Spital and Medical University of Vienna, Austria, report that women with higher

levels of anti-thyroid antibody had a significantly higher number of symptoms, even

though their levels of thyroid-stimulating hormone (TSH)—a measure of thyroid

function—did not differ from TSH levels measured in women with lower antibody

levels. In the article, “Hashimoto’s Thyroiditis Affects Symptom Load and

Quality of Life Unrelated to Hypothyroidism: A Prospective Case-Control Study

in Women Undergoing Thyroidectomy for Benign Goiter †the authors conclude that

hypothyroidism is only one factor contributing to HT symptoms.

“This study raises important clinical issues. Although the

authors did not study thyroid hormone treatment for Hashimoto’s thyroiditis, it

raises the possibility that optimal doses of thyroid hormone will not

completely ameliorate all symptoms. Further studies are required to confirm the

findings of Ott et al. and to determine if patients with hypothyroidism due to

Hashimoto’s thyroiditis still have residual symptoms despite achieving an ideal

biochemical response to thyroid hormone replacement therapy,†says H.

Emerson, MD, Editor-in-Chief of Thyroid and Professor Emeritus of Medicine at

the University of Massachusetts School of Medicine, in Worcester.

Study

Information:

Johannes Ott, Regina Promberger, Friedrich Kober,

Nikolaus Neuhold, Tea, Johannes C. Huber,

Hermann. Hashimoto's Thyroiditis Affects Symptom Load and Quality of Life

Unrelated to Hypothyroidism: A Prospective Case–Control Study in Women

Undergoing Thyroidectomy for Benign Goiter Thyroid, 2011 January

Volume: 21 Issue 2.

Kaiserin beth Spital and Medical University of Vienna, Austria.

From: thyroid treatment

[mailto:thyroid treatment ] On Behalf Of recent:lilian15@...

Sent: 07 April 2011 19:33

thyroid treatment

Subject: scientists play catch up

An interesting article from wellness resources.

http://www.wellnessresources.com/health/articles/scientists_play_catch_up_trying_to_understand_thyroid_problems/

Lilian