Guest guest Posted April 5, 2010 Report Share Posted April 5, 2010 At neutral pH saliva is super saturated with ca 2+ and phosphate and demineralisation can't occur, at low pH phosphates will disappear pH 5,5 and demineralisation will occur. So when u eat sugar u stimulate acid production by the viridens and mutans bacteria and demineralisation will be easier but saliva will buffer with carbonate to Restore pH so acid buffer reaction now cariogenesis occur when any alteration of this process will happen so check miller diagram (time, bacteria , susceptible surface and diet) Marc Sent from my BlackBerry® wireless deviceFrom: "dr_fatin1" <fatin952004@...>Date: Mon, 05 Apr 2010 10:50:13 -0000< >Subject: Help please Could anyone help me to find the answer for this Q cuze I've looked in all my books & didn't find the answer.Q: Outline the current theories of carcinogenesis?????Thanks Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 5, 2010 Report Share Posted April 5, 2010 hithe most accepted theory on carcinogenesis is field carcinogenesisbut others would be molecular progression and clonal evolution theories.On Mon, Apr 5, 2010 at 3:50 AM, dr_fatin1 <fatin952004@...> wrote: Could anyone help me to find the answer for this Q cuze I've looked in all my books & didn't find the answer. Q: Outline the current theories of carcinogenesis????? Thanks Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 5, 2010 Report Share Posted April 5, 2010 Hithis is the new cocept for carcinogenesis the molecular genetics which include apoptosis ,cytogenic abnormalitytelomerase & telomeres ,tumour oncogen & tumour suppression genTaghreed Could anyone help me to find the answer for this Q cuze I've looked in all my books & didn't find the answer. Q: Outline the current theories of carcinogenesis? ???? Thanks Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 5, 2010 Report Share Posted April 5, 2010 hi u mean cariogenensis or carcinogenesis?Tag Could anyone help me to find the answer for this Q cuze I've looked in all my books & didn't find the answer. Q: Outline the current theories of carcinogenesis? ???? Thanks Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 5, 2010 Report Share Posted April 5, 2010 Thank u for help but the Q about carcinogenesis not cariogenesis Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 5, 2010 Report Share Posted April 5, 2010 Hi please can any one help for answer these questions 1. The question about patient with aterial fibrillation with INR(3) was measured before one day & have periodontal abscess need exo what to do (do exo under local anaesth, refer to GP, refer to anticoagulant clinic, do drainage & send to oral surgery ,refer to oral surgery) 2. What is the topical anaesthesia with flavoured tast for child 3. Impression material for patient with gag reflex 4. Maximum time for dentist with physical impairment to leave from his profession 5. Death in uk from oral cancer each year 6. How do u review patient with smoking ( 3moths,6,12 etc) 7. Cement for cementation of tooth with mod restoration need crown(,GIC,zinc,phosphate,zinc polycarboxilate, composit,compomer) 8. what is the best cement for temporary crown (ZOE,GIC,zinc,phosphate,zinc polycarboxilate) 9. how many years does patient with radiotherapy is at risk of developing radionecrosis 10. patient with aids what is the first thing to do double gloves, go to GP, go to emergency department ,etcThanksTag Could anyone help me to find the answer for this Q cuze I've looked in all my books & didn't find the answer. Q: Outline the current theories of carcinogenesis? ???? Thanks Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 5, 2010 Report Share Posted April 5, 2010 Hithe answer is what I have answerd about molecular basis for carcinogenesisTagFrom: dr_fatin1 <fatin952004@...>Subject: Re: Help please Date: Monday, April 5, 2010, 6:31 PM Thank u for help but the Q about carcinogenesis not cariogenesis Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 5, 2010 Report Share Posted April 5, 2010 Hi for INR value we follow the UK INR target or Acceptable range please could any one help ? TagFrom: dr_fatin1 <fatin952004>Subject: Re: Help pleaseDate: Monday, April 5, 2010, 6:31 PM Thank u for help but the Q about carcinogenesis not cariogenesis Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 5, 2010 Report Share Posted April 5, 2010 Hi Tagreed It is 0,8-1,2 but if the pt on warfarin it is acceptable 2-3 SincerelyLyudmylaHuhley From: dr_fatin1 <fatin952004>Subject: Re: Help pleaseDate: Monday, April 5, 2010, 6:31 PM Thank u for help but the Q about carcinogenesis not cariogenesis Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 16, 2011 Report Share Posted August 16, 2011 Can you please tell me if my Thyroid levels are normal. They are. Serum TSH level (XaELV) Result 3.2 mu/l ( 0.5 – 4.7 Serum free T4 level 9 XaERr Result 16 pmol/L ( 9.0 – 24.0 ) Can you explain what all this means please. I had Radio Iodine Treatment in 2007 to remove my Thyroid, as it was over active. I am prescribed 50mcg and 23 mcg. I take 50mcg each day, but after a while become very tired bloated and have constipation. I then take 75mcg for a few days and am ok, and feel better, but if i take this dosage for too long, i then start to have the symptoms of an over active Thyroid. My question is. Am i ok to take the extra 25mcg, when i start to feel sluggish. I have tried to talk to my doctor about this, but seem to be getting no-where. I have only just been able to start taking an active interest in this, as a year after having the Radio Iodine, i developed a Leiomyosarcoma in my thigh, and have had all that to deal with. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 17, 2011 Report Share Posted August 17, 2011 TSH too high - should be around 1.0 Serum free T4 looks fine. You need free T3 testing. Also, you may be suffering with one of the associated conditions that go along with being hypothyroid. See below - if any of these are a problem you will not be able to utilise the thyroid hormone at the cellular level - and it looks like this is your problem. The Thyroxine is probably lying in your blood with nowhere to go. You should ask your doctor (before increasing your levothyroxine dose) to test your levels of the specific minerals and vitamins mentioned before and when the results have come back, ask for these together with the reference range and post them here so we can help with their interpretation. There are MANY reasons and many medical conditions associated with thyroid disease that stop thyroid hormone from getting into the cells, where it does its work. I mention these over and over and over again - ad nauseum - people must be bored with the same old, same old but as each new member joins us, they need to know. The main condition responsible for stopping thyroid hormone from working, is, quite simply, a patients thyroxine dose is too low because the doctor or consultant refuses to increase it, because the serum thyroid function test results appear OK. Sometimes, the thyroxine dose is too high, yet patients still don't feel well. They continue to suffer. Some reasons for this: They may be suffering with low adrenal reserve. The production of T4, its conversion to T3, and the receptor uptake requires a normal amount of adrenal hormones, notably, of course, cortisone. (Excess cortisone can shut production down, however.) This is what happens if the adrenals are not responding properly, and provision of cortisone usually switches it on again. But sometimes it doesn’t. If the illness has been going on for a long time, the enzyme seems to fail. This conversion failure (inexplicably denied by many endocrinologists) means the thyroxine builds up, unconverted. So it doesn’t work, and T4 toxicosis results. This makes the patient feel quite unwell, toxic, often with palpitations and chest pain. If provision of adrenal support doesn’t remedy the situation, the final solution is the use of the active thyroid hormone, already converted, T3 - either synthetic or natural. Then, we have systemic candidiasis. This is where candida albicans, a yeast, which causes skin infections almost anywhere in the body, invades the lining of the lower part of the small intestine and the large intestine. Here, the candida sets up residence in the warmth and the dark, and demands to be fed. Loving sugars and starches, candida can make you suffer terrible sweet cravings. Candida can produce toxins which can cause very many symptoms of exhaustion, headache, general illness, and which interfere with the uptake of thyroid and adrenal treatment. Sometimes the levels - which we usually test for - can be very high, and make successful treatment difficult to achieve until adequately treated. Then there is receptor resistance which could be a culprit. Being hypothyroid for some considerable time may mean the biochemical mechanisms which permit the binding of T3 to the receptors, is downgraded - so the T3 won’t go in. With slow build up of T3, with full adrenal support and adequate vitamins and minerals, the receptors do come on line again. But this can be quite a slow process, and care has to be taken to build the dose up gradually. And then there are Food allergies. The most common food allergy is allergy to gluten, the protein fraction of wheat. The antibody generated by the body, by a process of molecular mimicry, cross reacts with the thyroperoxidase enzyme, (which makes thyroxine) and shuts it down. So allergy to bread can make you hypothyroid. There may be other food allergies with this kind of effect, but information on these is scanty. Certainly allergic response to certain foods can affect adrenal function and imperil thyroid production and uptake. Then we have hormone imbalances. The whole of the endocrine system is linked; each part of it needs the other parts to be operating normally to work properly. An example of this we have seen already, with cortisone. But another example is the operation of sex hormones. The imbalance that occurs at the menopause with progesterone running down, and a relative dominance of oestrogen is a further case in point – oestrogen dominance downgrades production, transportation and uptake of thyroid hormones. This is why hypothyroidism may first appear at the menopause; the symptoms ascribed to this alone, which is then treated – often with extra oestrogen, making the whole thing worse. Deficiency in progesterone most especially needs to be dealt with, since it reverses oestrogen dominance, improves many menopausal symptoms like sweats and mood swings, and reverses osteoporosis. Happily natural progesterone cream is easily obtained: when used it has the added benefit of helping to stabilise adrenal function. Then, we must never forget the possibility of mercury poisoning (through amalgam fillings) - low levels of ferritin, vitamin B12, vitamin D3, magnesium, folate, copper and zinc - all of which, if low, stop the thyroid hormone from being utilised by the cells - these have to be treated. As Dr Peatfield says " When you have been quite unwell for a long time, all these problems have to be dealt with; and since each may affect the other, it all has to be done rather carefully. Contrary to cherished beliefs by much of the medical establishment, the correction of a thyroid deficiency state has a number of complexities and variables, which make the treatment usually quite specific for each person. The balancing of these variables is as much up to you as to me – which is why a check of morning, day and evening temperatures and pulse rates, together with symptoms, good and bad, can be so helpful. Many of you have been ill for a long time, either because you have not been diagnosed, or the treatment leaves you still quite unwell. Those of you who have relatively mild hypothyroidism, and have been diagnosed relatively quickly, may well respond to synthetic thyroxine, the standard treatment. I am therefore unlikely to see you; since if the thyroxine proves satisfactory in use, it is merely a question of dosage. For many of you, the outstanding problem is not that the diagnosis has not been made – although, extraordinarily, this is disgracefully common – but that is has, and the thyroxine treatment doesn’t work. The dose has been altered up and down, and clinical improvement is variable and doesn’t last, in spite of blood tests, which say you are perfectly all right (and therefore you are actually depressed and need this fine antidepressant). The above problems must be eliminated if thyroid hormone isn't working for you. Luv - Sheila Can you please tell me if my Thyroid levels are normal. They are. Serum TSH level (XaELV) Result 3.2 mu/l ( 0.5 – 4.7 Serum free T4 level 9 XaERr Result 16 pmol/L ( 9.0 – 24.0 ) Can you explain what all this means please. I had Radio Iodine Treatment in 2007 to remove my Thyroid, as it was over active. I am prescribed 50mcg and 23 mcg. I take 50mcg each day, but after a while become very tired bloated and have constipation. I then take 75mcg for a few days and am ok, and feel better, but if i take this dosage for too long, i then start to have the symptoms of an over active Thyroid. My question is. Am i ok to take the extra 25mcg, when i start to feel sluggish. I have tried to talk to my doctor about this, but seem to be getting no-where. I have only just been able to start taking an active interest in this, as a year after having the Radio Iodine, i developed a Leiomyosarcoma in my thigh, and have had all that to deal with. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 10, 2011 Report Share Posted October 10, 2011 > > > > Hi everyone > > Hope u are doing great > > Does anyone know how can I apply for a temporary registration post? > > Recently moved back to Uk. > > Best regards > > Ebtisam > Quote Link to comment Share on other sites More sharing options...
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