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At neutral pH saliva is super saturated with ca 2+ and phosphate and demineralisation can't occur, at low pH phosphates will disappear pH 5,5 and demineralisation will occur. So when u eat sugar u stimulate acid production by the viridens and mutans bacteria and demineralisation will be easier but saliva will buffer with carbonate to Restore pH so acid buffer reaction now cariogenesis occur when any alteration of this process will happen so check miller diagram (time, bacteria , susceptible surface and diet) Marc Sent from my BlackBerry® wireless deviceFrom: "dr_fatin1" <fatin952004@...>Date: Mon, 05 Apr 2010 10:50:13 -0000< >Subject: Help please Could anyone help me to find the answer for this Q cuze I've looked in all my books & didn't find the answer.Q: Outline the current theories of carcinogenesis?????Thanks

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hithe most accepted theory on carcinogenesis is field carcinogenesisbut others would be molecular progression and clonal evolution theories.On Mon, Apr 5, 2010 at 3:50 AM, dr_fatin1 <fatin952004@...> wrote:

 

Could anyone help me to find the answer for this Q cuze I've looked in all my books & didn't find the answer.

Q: Outline the current theories of carcinogenesis?????

Thanks

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Hithis is the new cocept for carcinogenesis the molecular genetics which include apoptosis ,cytogenic abnormalitytelomerase & telomeres ,tumour oncogen & tumour suppression genTaghreed

Could anyone help me to find the answer for this Q cuze I've looked in all my books & didn't find the answer.

Q: Outline the current theories of carcinogenesis? ????

Thanks

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hi u mean cariogenensis or carcinogenesis?Tag

Could anyone help me to find the answer for this Q cuze I've looked in all my books & didn't find the answer.

Q: Outline the current theories of carcinogenesis? ????

Thanks

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Hi please can any one help for answer these questions

1.

The question about patient with

aterial fibrillation with INR(3) was measured before one day & have periodontal abscess need exo what to do

(do exo under local anaesth,

refer to GP, refer to anticoagulant clinic, do drainage & send to oral

surgery ,refer to oral surgery)

2.

What is the topical anaesthesia

with flavoured tast for child

3.

Impression material for

patient with gag reflex

4.

Maximum time for dentist

with physical impairment to leave from his profession

5.

Death in uk from oral

cancer each year

6.

How do u review patient

with smoking ( 3moths,6,12 etc)

7.

Cement for cementation of tooth

with mod restoration need crown(,GIC,zinc,phosphate,zinc

polycarboxilate, composit,compomer)

8.

what is the best cement for

temporary crown (ZOE,GIC,zinc,phosphate,zinc polycarboxilate)

9.

how many years does patient

with radiotherapy is at risk of developing radionecrosis

10.

patient with aids what is

the first thing to do

double gloves,

go to GP, go to emergency department ,etcThanksTag

Could anyone help me to find the answer for this Q cuze I've looked in all my books & didn't find the answer.

Q: Outline the current theories of carcinogenesis? ????

Thanks

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Hithe answer is what I have answerd about molecular basis for carcinogenesisTagFrom: dr_fatin1 <fatin952004@...>Subject: Re: Help please Date: Monday, April 5, 2010, 6:31 PM

Thank u for help but the Q about carcinogenesis not cariogenesis

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Hi for INR value we follow the UK INR target or Acceptable range please could any one help ? TagFrom: dr_fatin1 <fatin952004>Subject: Re: Help pleaseDate: Monday, April 5, 2010, 6:31 PM

Thank u for help but the Q about carcinogenesis not cariogenesis

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Hi Tagreed

It is 0,8-1,2 but if the pt on warfarin it is acceptable 2-3

SincerelyLyudmylaHuhley

From: dr_fatin1 <fatin952004>Subject: Re: Help pleaseDate: Monday, April 5, 2010, 6:31 PM

Thank u for help but the Q about carcinogenesis not cariogenesis

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  • 1 year later...

Can you please tell me if my Thyroid levels are normal. They are.

Serum TSH level (XaELV) Result 3.2 mu/l ( 0.5 – 4.7

Serum free T4 level 9 XaERr Result 16 pmol/L ( 9.0 – 24.0 )

Can you explain what all this means please.

I had Radio Iodine Treatment in 2007 to remove my Thyroid, as it was over

active. I am prescribed 50mcg and 23 mcg. I take 50mcg each day, but after a

while become very tired bloated and have constipation. I then take 75mcg for a

few days and am ok, and feel better, but if i take this dosage for too long, i

then start to have the symptoms of an over active Thyroid. My question is. Am i

ok to take the extra 25mcg, when i start to feel sluggish. I have tried to talk

to my doctor about this, but seem to be getting no-where. I have only just been

able to start taking an active interest in this, as a year after having the

Radio Iodine, i developed a Leiomyosarcoma in my thigh, and have had all that to

deal with.

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TSH too high - should be around 1.0

Serum free T4 looks fine.

You need free T3 testing.

Also, you may be suffering with one of the associated conditions

that go along with being hypothyroid. See below - if any of these are a problem

you will not be able to utilise the thyroid hormone at the cellular level - and

it looks like this is your problem. The Thyroxine is probably lying in your

blood with nowhere to go.

You should ask your doctor (before increasing your levothyroxine

dose) to test your levels of the specific minerals and vitamins mentioned

before and when the results have come back, ask for these together with the

reference range and post them here so we can help with their interpretation.

There are MANY reasons and many medical conditions associated

with thyroid disease that stop thyroid hormone from getting into the cells,

where it does its work. I mention these over and over and over again - ad

nauseum - people must be bored with the same old, same old but as each new

member joins us, they need to know.

The main condition responsible for stopping thyroid hormone from

working, is, quite simply, a patients thyroxine dose is too low because the

doctor or consultant refuses to increase it, because the serum thyroid function

test results appear OK. Sometimes, the thyroxine dose is too high, yet patients

still don't feel well. They continue to suffer. Some reasons for this:

They may be suffering with low adrenal reserve. The production

of T4, its conversion to T3, and the receptor uptake requires a normal amount

of adrenal hormones, notably, of course, cortisone. (Excess cortisone can shut

production down, however.) This is what happens if the adrenals are not

responding properly, and provision of cortisone usually switches it on

again. But sometimes it doesn’t. If the illness has been

going on for a long time, the enzyme seems to fail. This conversion

failure (inexplicably denied by many endocrinologists) means the thyroxine

builds up, unconverted. So it doesn’t work, and T4 toxicosis

results. This makes the patient feel quite unwell, toxic, often with

palpitations and chest pain. If provision of adrenal support doesn’t

remedy the situation, the final solution is the use of the active thyroid

hormone, already converted, T3 - either synthetic or natural.

Then, we have systemic candidiasis. This is where candida

albicans, a yeast, which causes skin infections almost anywhere in the body,

invades the lining of the lower part of the small intestine and the large

intestine. Here, the candida sets up residence in the warmth and the

dark, and demands to be fed. Loving sugars and starches, candida can make

you suffer terrible sweet cravings. Candida can produce toxins which can

cause very many symptoms of exhaustion, headache, general illness, and which

interfere with the uptake of thyroid and adrenal treatment. Sometimes the

levels - which we usually test for - can be very high, and make successful

treatment difficult to achieve until adequately treated.

Then there is receptor resistance which could be a culprit. Being

hypothyroid for some considerable time may mean the biochemical mechanisms

which permit the binding of T3 to the receptors, is downgraded - so the T3

won’t go in. With slow build up of T3, with full adrenal support

and adequate vitamins and minerals, the receptors do come on line again.

But this can be quite a slow process, and care has to be taken to build the

dose up gradually.

And then there are Food allergies. The most common food allergy

is allergy to gluten, the protein fraction of wheat. The antibody generated by

the body, by a process of molecular mimicry, cross reacts with the

thyroperoxidase enzyme, (which makes thyroxine) and shuts it down. So

allergy to bread can make you hypothyroid. There may be other food allergies

with this kind of effect, but information on these is scanty. Certainly

allergic response to certain foods can affect adrenal function and imperil

thyroid production and uptake.

Then we have hormone imbalances. The whole of the endocrine

system is linked; each part of it needs the other parts to be operating

normally to work properly. An example of this we have seen already, with

cortisone. But another example is the operation of sex hormones.

The imbalance that occurs at the menopause with progesterone running down, and

a relative dominance of oestrogen is a further case in point – oestrogen

dominance downgrades production, transportation and uptake of thyroid

hormones. This is why hypothyroidism may first appear at the menopause;

the symptoms ascribed to this alone, which is then treated – often with

extra oestrogen, making the whole thing worse. Deficiency in progesterone

most especially needs to be dealt with, since it reverses oestrogen dominance,

improves many menopausal symptoms like sweats and mood swings, and reverses

osteoporosis. Happily natural progesterone cream is easily obtained: when

used it has the added benefit of helping to stabilise adrenal function.

Then, we must never forget the possibility of mercury poisoning

(through amalgam fillings) - low levels of ferritin, vitamin B12, vitamin D3,

magnesium, folate, copper and zinc - all of which, if low, stop the thyroid

hormone from being utilised by the cells - these have to be treated.

As Dr Peatfield says " When you have been quite unwell for a

long time, all these problems have to be dealt with; and since each may affect

the other, it all has to be done rather carefully.

Contrary to cherished beliefs by much of the medical

establishment, the correction of a thyroid deficiency state has a number of

complexities and variables, which make the treatment usually quite specific for

each person. The balancing of these variables is as much up to you as to

me – which is why a check of morning, day and evening temperatures and

pulse rates, together with symptoms, good and bad, can be so helpful.

Many of you have been ill for a long time, either because you

have not been diagnosed, or the treatment leaves you still quite unwell.

Those of you who have relatively mild hypothyroidism, and have been diagnosed

relatively quickly, may well respond to synthetic thyroxine, the standard

treatment. I am therefore unlikely to see you; since if the thyroxine

proves satisfactory in use, it is merely a question of dosage.

For many of you, the outstanding problem is not that the

diagnosis has not been made – although, extraordinarily, this is

disgracefully common – but that is has, and the thyroxine treatment

doesn’t work. The dose has been altered up and down, and clinical

improvement is variable and doesn’t last, in spite of blood tests, which

say you are perfectly all right (and therefore you are actually depressed and

need this fine antidepressant).

The above problems must be eliminated if thyroid hormone isn't

working for you.

Luv - Sheila

Can you please tell me if my Thyroid levels are

normal. They are.

Serum TSH level (XaELV) Result 3.2 mu/l ( 0.5 – 4.7

Serum free T4 level 9 XaERr Result 16 pmol/L ( 9.0 – 24.0 )

Can you explain what all this means please.

I had Radio Iodine Treatment in 2007 to remove my Thyroid, as it was over

active. I am prescribed 50mcg and 23 mcg. I take 50mcg each day, but after a

while become very tired bloated and have constipation. I then take 75mcg for a

few days and am ok, and feel better, but if i take this dosage for too long, i

then start to have the symptoms of an over active Thyroid. My question is. Am i

ok to take the extra 25mcg, when i start to feel sluggish. I have tried to talk

to my doctor about this, but seem to be getting no-where. I have only just been

able to start taking an active interest in this, as a year after having the

Radio Iodine, i developed a Leiomyosarcoma in my thigh, and have had all that

to deal with.

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  • 1 month later...

>

>

>

> Hi everyone

>

> Hope u are doing great

>

> Does anyone know how can I apply for a temporary registration post?

>

> Recently moved back to Uk.

>

> Best regards

>

> Ebtisam

>

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