Learn More About Indole 3 Carbinol

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Article Title: Learn More About Indole 3 Carbinol

Author: Bandes

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“Eat your brussel sprouts!”

Mom really did have a great reason for forcing us to eat those

horrible vegetables but I bet she didn’t even know the full

benefits.

It turns out that cruciferous vegetables including broccoli,

cauliflower, brussel sprouts and cabbage contain Indole 3

Carbinol (I3C). I3C is the reason our moms were so strongly

encouraging us to eat up.

Since being discovered, Indole 3 Carbinol has been used in many

studies that suggest several health benefits, especially for

women. Oral ingestion of Indole 3 Carbinol has been shown to

alter the metabolism of estrogen in a beneficial manner. As we

know from hormone replacement therapy (HRT) studies, excess

estrogen in the body can be damaging. It’s fairly common

knowledge that HRT can increase the risks of most gynecological

cancers including endometrial, ovarian and breast cancer as well

as increasing the risks of heart attacks and stroke. HRT can

also induce PMS type symptoms including bloating, breast

tenderness, moodiness and irritability and water retention.

So, if all these things can occur because of an increase in

estrogen, maybe we should understand a little better what it is

that is causing this to happen. Here is a little Biology 101.

Both male and female bodies have estrogen receptors. These

receptors are like electrical outlets. The purpose of estrogen

receptors is to receive estrogen and allow the body to process

the estrogen. Just like there are many different things that

you could plug into an electrical outlet, there are several

different types of estrogen that can plug into estrogen

receptors. In the case of electrical outlets, various things

will pull different amounts of power such as the difference

between a night light and a computer. Obviously, the computer

will draw much more power than the night light, but the least

amount of power will be drawn from one of those little plastic

safety plugs.

Back to the estrogen receptors. Different forms of estrogen;

phytoestrogen, estriol, estrone, estradiol and xenoestrogens,

have different effects when plugged into those estrogen

receptors. The weaker the estrogen, the less estrogenic effects

they will have on the body. The stronger the estrogen, the more

negative effects they will have on health. But just as any

house has a limited number of electrical outlets, the body has

a limited number of estrogen receptors.

Ideally we want to plug as many estrogen receptors as possible

with weak estrogens, primarily phytoestrogens which come from

plant sources. HRT and hormonal birth control methods all use

the strongest natural estrogen, estradiol. Indole 3 Carbinol

mimics the weakest forms of estrogen. Therefore, the more

Indole 3 Carbinol that is absorbed by the body and used to plug

the estrogen receptors, less receptors will be available to the

stronger estrogens.

Studies indicate that Indole 3 Carbinol is more beneficial than

Tamoxifen for the prevention of breast cancer1. This may be due

to I3C's ability to mimic very weak estrogen in the body.

Studies have also indicated that Indole 3 Carbinol was

beneficial to mice suffering from Lupus and other autoimmune

disorders2.

Other studies indicate that Indole 3 Carbinol may be beneficial

for the following concerns.

• Ovarian cancer

• Prostate cancer

• Colon cancer

• Human Papilloma Virus (HVP)

• Cervical dysplasia3

In addition, because of the ability Indole 3 Carbinol seems to

have on estrogen, case studies are now showing it may be

beneficial for:

• Hot flashes and other menopausal symptoms

• Breast tenderness, cramping and other menstrual symptoms

• Helping to relieve muscle soreness do to exercise or

overexertion.

With so much contributing to the numerous benefits of Indole 3

Carbinol, it may be time to start listening to mom and eat

those veggies!

1. “Prevention and treatment of cancer with indole-3-carbinol”,

Alternative Medicine Review, Dec, 2001 by S. Brignall

2. “Indole-3-carbinol in women with SLE: effect on estrogen

metabolism and disease activity”, Lupus, Volume 10, Number 11,

November 2001, pp. 779-783(5)

3. “Placebo-controlled trial of indole-3-carbinol in the

treatment of CIN”, Gynecol Oncol. 2000 Aug;78(2):123-9

About The Author: Bandes is a Certified Herb Specialist

that has been helping others to regain their health and

vitality since 1999. uses and recommends Nature’s

Sunshine Products Indole 3 Carbinol for her family and friends.

Read more articles by at http://www.naturallyherbs.com.

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