Guest guest Posted January 3, 2012 Report Share Posted January 3, 2012 Hello all, Before the Christmas break, someone mentioned that they took TMG with wondrous results -- loss of belly fat and a return of ankles. I could definitely use both of those! I know that TMG is not a part of the "bare minimum" iodine protocol, but is it helpful? What dose should be taken? Do we take it forever or just for a while? Thank you! Toni Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 3, 2012 Report Share Posted January 3, 2012 Hi Toni, I take TMG to support methylation because I suspect I have the mthfr gene problem. The iodine protocol recommends the methylated form of selenium. Since I was treating non-alcoholic fatty liver before starting the iodine protocol to treat my thyroid nodule it all kind of came together into one protocol for me to use the b complex vitamins and selenium in methylated forms. I also use milk thistle for my liver detox. I take 2000 mg of TMG and it really did make a difference. I think takes DMG as part of her supplementation. I don't know which is better. Perhaps she can explain if she sees this. Good luck to you, Kari From: "tonicollin@..." <tonicollin@...>iodine Sent: Tuesday, January 3, 2012 4:43 PMSubject: TMG and iodine Hello all, Before the Christmas break, someone mentioned that they took TMG with wondrous results -- loss of belly fat and a return of ankles. I could definitely use both of those! I know that TMG is not a part of the "bare minimum" iodine protocol, but is it helpful? What dose should be taken? Do we take it forever or just for a while? Thank you! Toni Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 3, 2012 Report Share Posted January 3, 2012  It is my understanding that DMG is a byproduct of the enzyme reaction of TMG. When my doctor was formulating his product he talked to some specialists and they said that it was better to use DMG than TMG so that's what he used. I have never tried TMG. Methylation issues are complex. Buist, ND HC TMG and iodine Hello all, Before the Christmas break, someone mentioned that they took TMG with wondrous results -- loss of belly fat and a return of ankles. I could definitely use both of those! I know that TMG is not a part of the "bare minimum" iodine protocol, but is it helpful? What dose should be taken? Do we take it forever or just for a while? Thank you! Toni Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 3, 2012 Report Share Posted January 3, 2012 Thanks for responding . I tried to post this in the OT group but returned it. Don't know why but I thought this may be interesting info for those that need to decide on what supporting supplements to use. I found this on another forum: http://www.healthyawareness.com/articles/about-liver-health/same-tmg-dmg-and-the-liver.aspx I think the reason I was drawn to TMG was for liver detox support. Someone named Polly explained this nicely. Polly: TMG stands for tri-methyl-glycine. Some of its properties seem to relate to its ability to increase SAMe (S-Adenosyl-Methionine) levels, and some of its properties seem to relate to methylation and its ability to convert into glycine and DMG (di-methyl-glycine). You will find a lot of information about TMG, DMG and glycine in Dr. Braverman’s book on amino acids. Here are a few properties of TMG that I find interesting. 1) Improved Liver Function: One of my doctors likes to use TMG for his patients that have liver problems. According to him, one of TMG’s biggest advantages is that it greatly increases the production of SAMe. The liver needs SAMe to perform many of its detoxification functions. Another benefit for the liver is the lipotropic nature of TMG --- it helps get rid of fat deposits in the liver. Another benefit is TMG’s ability to increase bile salts and bile production by the liver. Bile emulsifies fat so it can be absorbed and bile carries toxins out of the liver into the intestines for disposal. 2) Improved Mood: The first time I took TMG, I noticed a definite improvement in mood, possibly because of the increase in SAMe levels. However, there is a possibility that large doses of TMG could have an opposite effect and cause depression. This has been observed with DMG, which is created from TMG. (See page 305 of Braverman’s book on amino acids where he is talking about 3 grams of DMG.) Also he says that large doses of SAMe have been a problem with bi-polar depression. This might have something to do with the increased methylation. Please be aware of another potential problem with SAMe. SAMe, DMG and TMG must be kept in balance with folic acid and B12. 3) Enhanced Nerve Function: When I take TMG, I notice a definite improvement in my handwriting. (I didn’t notice a thing from plain glycine.) Someone at this forum found TMG helpful for her carpal tunnel syndrome. These effects might be related to TMG’s ability to increase SAMe because SAMe supports normal neural function. SAMe also helps convert CoA into acetylcholine, which is required for nerve transmissions. See www.megson.com. 4) A Source Of Methyl Groups: TMG acts as a source of methyl groups. Methyl groups are needed for the proper formation and function of many things like vitamins, hormones, enzymes, and neurotransmitters such as epinephrine. The methyl groups are also needed for RNA production for protein synthesis. Methylation is often inhibited by mercury poisoning. [13] Here are a few notes I took from a tape on methylation that I viewed at my doctor’s office: A methyl group is a carbon and three hydrogen atoms. Choline, TMG, and DMG have methyl groups. Folate helps make methyl groups, and B12 transfers methyl groups. SAMe is the body’s actual methyl donor. Methylation prevents DNA breakdown. 5) Reduces homocysteine levels: TMG helps lower homocysteine levels by providing a methyl group needed to convert homocysteine back into the sulfur amino acid methionine. High homocysteine levels are associated with heart disease and the birth defect spinal bifida. When B12, folic acid and B6 prove inadequate to lowering homocysteine levels, the addition of TMG often brings the homocysteine levels down. Yet, don’t think SAMe will have the same effect on homocysteine. A supplement of SAMe without these other factors present could actually increase homocysteine. From: " Buist, ND HC" <stephaniebnd@...>iodine Sent: Tuesday, January 3, 2012 11:00 PMSubject: Re: TMG and iodine  It is my understanding that DMG is a byproduct of the enzyme reaction of TMG. When my doctor was formulating his product he talked to some specialists and they said that it was better to use DMG than TMG so that's what he used. I have never tried TMG. Methylation issues are complex. Buist, ND HC TMG and iodine Hello all, Before the Christmas break, someone mentioned that they took TMG with wondrous results -- loss of belly fat and a return of ankles. I could definitely use both of those! I know that TMG is not a part of the "bare minimum" iodine protocol, but is it helpful? What dose should be taken? Do we take it forever or just for a while? Thank you! Toni Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 3, 2012 Report Share Posted January 3, 2012 Where could we learn more about Methylation issues?On Wed, Jan 4, 2012 at 3:00 PM, Buist, ND HC <stephaniebnd@...> wrote:   It is my understanding that DMG is a byproduct of the enzyme reaction of TMG. When my doctor was formulating his product he talked to some specialists and they said that it was better to use DMG than TMG so that's what he used. I have never tried TMG. Methylation issues are complex.  Buist, ND HC TMG and iodine  Hello all,  Before the Christmas break, someone mentioned that they took TMG with wondrous results -- loss of belly fat and a return of ankles. I could definitely use both of those!  I know that TMG is not a part of the " bare minimum " iodine protocol, but is it helpful? What dose should be taken? Do we take it forever or just for a while?  Thank you!   Toni Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 4, 2012 Report Share Posted January 4, 2012 Methylation is a topic of Holford The Optimum Nutrition Bible, also www.patrickholford.com http://www.youtube.com/user/HeadTrashTV?feature=mhee(RR) turning the psychological world on its head for the betterhttp://twitter.com/ChrisMilbankhttp://headtrash.co.uk/the-mission/http://www.youtube.com/watch?v=RLQpRrsQ1Zw & feature=relatedhttp://headtrash.ning.com/ this is a RR and Head Trash chat and blog community u tube video of Reflective Repatterning course students From: Cochrane <juliemc9@...>iodine Sent: Wednesday, 4 January 2012, 5:49Subject: Re: TMG and iodine Where could we learn more about Methylation issues? On Wed, Jan 4, 2012 at 3:00 PM, Buist, ND HC <stephaniebnd@...> wrote:  It is my understanding that DMG is a byproduct of the enzyme reaction of TMG. When my doctor was formulating his product he talked to some specialists and they said that it was better to use DMG than TMG so that's what he used. I have never tried TMG. Methylation issues are complex. Buist, ND HC TMG and iodine Hello all, Before the Christmas break, someone mentioned that they took TMG with wondrous results -- loss of belly fat and a return of ankles. I could definitely use both of those! I know that TMG is not a part of the "bare minimum" iodine protocol, but is it helpful? What dose should be taken? Do we take it forever or just for a while? Thank you! Toni Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 5, 2012 Report Share Posted January 5, 2012 Thank you to everyone for the information on TMG. This looks like a really hopeful avenue for me to explore. Toni In a message dated 1/4/2012 8:35:38 P.M. Pacific Standard Time, iodine writes: Re: TMG and iodine Posted by: "Kari" kari0761@... kari0761 Wed Jan 4, 2012 3:56 pm (PST) Thanks for responding . I tried to post this in the OT group but returned it. Don't know why but I thought this may be interesting info for those that need to decide on what supporting supplements to use. I found this on another forum: http://www.healthyawareness.com/articles/about-liver-health/same-tmg-dmg-and-the-liver.aspx I think the reason I was drawn to TMG was for liver detox support. Someone named Polly explained this nicely. Polly: TMG stands for tri-methyl-glycine. Some of its properties seem to relate to its ability to increase SAMe (S-Adenosyl-Methionine) levels, and some of its properties seem to relate to methylation and its ability to convert into glycine and DMG (di-methyl-glycine). You will find a lot of information about TMG, DMG and glycine in Dr. Braverman’s book on amino acids. Here are a few properties of TMG that I find interesting.1) Improved Liver Function: One of my doctors likes to use TMG for his patients that have liver problems. According to him, one of TMG’s biggest advantages is that it greatly increases the production of SAMe. The liver needs SAMe to perform many of its detoxification functions. Another benefit for the liver is the lipotropic nature of TMG --- it helps get rid of fat deposits in the liver. Another benefit is TMG’s ability to increase bile salts and bile production by the liver. Bile emulsifies fat so it can be absorbed and bile carries toxins out of the liver into the intestines for disposal.2) Improved Mood: The first time I took TMG, I noticed a definite improvement in mood, possibly because of the increase in SAMe levels. However, there is a possibility that large doses of TMG could have an opposite effect and cause depression. This has been observed with DMG, which is created from TMG. (See page 305 of Braverman’s book on amino acids where he is talking about 3 grams of DMG.) Also he says that large doses of SAMe have been a problem with bi-polar depression. This might have something to do with the increased methylation. Please be aware of another potential problem with SAMe. SAMe, DMG and TMG must be kept in balance with folic acid and B12.3) Enhanced Nerve Function: When I take TMG, I notice a definite improvement in my handwriting. (I didn’t notice a thing from plain glycine.) Someone at this forum found TMG helpful for her carpal tunnel syndrome. These effects might be related to TMG’s ability to increase SAMe because SAMe supports normal neural function. SAMe also helps convert CoA into acetylcholine, which is required for nerve transmissions. See www.megson.com.4) A Source Of Methyl Groups: TMG acts as a source of methyl groups. Methyl groups are needed for the proper formation and function of many things like vitamins, hormones, enzymes, and neurotransmitters such as epinephrine. The methyl groups are also needed for RNA production for protein synthesis. Methylation is often inhibited by mercury poisoning. [13] Here are a few notes I took from a tape on methylation that I viewed at my doctor’s office: A methyl group is a carbon and three hydrogen atoms. Choline, TMG, and DMG have methyl groups. Folate helps make methyl groups, and B12 transfers methyl groups. SAMe is the body’s actual methyl donor. Methylation prevents DNA breakdown.5) Reduces homocysteine levels: TMG helps lower homocysteine levels by providing a methyl group needed to convert homocysteine back into the sulfur amino acid methionine. High homocysteine levels are associated with heart disease and the birth defect spinal bifida. When B12, folic acid and B6 prove inadequate to lowering homocysteine levels, the addition of TMG often brings the homocysteine levels down. Yet, don’t think SAMe will have the same effect on homocysteine. A supplement of SAMe without these other factors present could actually increase homocysteine.________________________________From: " Buist, ND HC" <stephaniebndatt (DOT) net>iodine Sent: Tuesday, January 3, 2012 11:00 PMSubject: Re: TMG and iodine  It is my understanding that DMG is a byproduct of the enzyme reaction of TMG. When my doctor was formulating his product he talked to some specialists and they said that it was better to use DMG than TMG so that's what he used. I have never tried TMG. Methylation issues are complex. Buist, ND HC TMG and iodine>>> >Hello all,>>Before the Christmas break, someone mentioned that they took TMG with wondrous results -- loss of belly fat and a return of ankles. I could definitely use both of those!>>I know that TMG is not a part of the "bare minimum" iodine protocol, but is it helpful? What dose should be taken? Do we take it forever or just for a while?>>Thank you!> Toni >> Back to top Reply to sender | Reply to group | Reply via web post Messages in this topic (45) 6.2. Re: TMG and iodine Posted by: " Milbank" milbankchristopher@... milbankchristopher Wed Jan 4, 2012 3:56 pm (PST) Methylation is a topic of Holford The Optimum Nutrition Bible, also www.patrickholford.com Quote Link to comment Share on other sites More sharing options...
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