Re: The plot thickens ..

[Guest guest]

Hi Dawn

You can read about elevated

Alkaline phosphates here http://labtestsonline.org/understanding/analytes/alp/tab/test

- High ALP usually means that either the liver has been damaged or a condition

causing increased bone cell activity is present. If other liver tests such as bilirubin,

aspartate

aminotransferase (AST), or alanine

aminotransfere (ALT) are also high, usually the ALP is coming from the liver.

If calcium

and phosphorus

measurements are abnormal, usually the ALP is coming from bone. If a GGT or

5'-nucleotidase is also increased, then the high ALP is likely due to liver

disease. If either of these two tests is normal, then the high ALP is

likely due to a bone condition. Read on…..

Also, check out http://labtestsonline.org/understanding/analytes/igf1/tab/test#what

- this could tie in with the high ALP and probably liver disease. Let us

know the results of the current investigation.

It could be that your thyroid

problems have been cleared by the adrenal supplements you have been taking. Can

you remind us what these are and the doses please.

Luv - Sheila

Does anyone else have elevated Alkaline phosphates-

389 (Range 105-340) which has been persistant now for 4-5 years. Now along with

that is a very low igf 1- 60 (90-264). This is currently being investigated by

the endo. I have come off the Thyroxine (which had made me toxic). Now Im on

nothing as we wait to see what happens to my low TSH. Interestingly since

stopping this has come up to 2.4 Previously tsh 0.17 in range (0.27-4.2) My FT4

has gone up slightly as well from 13.91 to 14.5 :-0 And this is all without

thyroid Meds. I have been off it now about 8 weeks, but am on Adrenal

Supplements and feeling somewhat better.

I have just had Iron Studies, another TSH & T4, IGF 1 again, ZPP (I think

this is for zinc/lead poisoning), and Vit D.

I guess Im asking if anyone else has had alkaline phosphates problems, and

could they be related to my thyroid. I also have pernicious anaemia.

Any other suggestions/thoughts would be welcome.

Thanks

Dawn2

[Guest guest]

Thanks Sheila..

Well I had been on Nutri Adrenal (normal) 2od. for about 3 months, altho after a

recent consultation with Dr Peatfield, I have gone on to 2 Nutri Adrenal X.

Have also started on 5mg Prednisone and DHEA -7 Keto 25mg of. I am feeling as

though the 'light has been switched back on'. My thinking clearer, spring in my

step etc. Now I am aware this could be the steroids ?? (I have only been on the

steroids and DHEA for 4 weeks ?? ) My morning temp has gone from being between

34-35 to lower end of 36. And I can really tell. Of course the 'real test' is

if I can re-start work shortly, after being off for 5 months.

I havent admitted to my Endo that I have started on steroids and dhea. He wants

me to come off the Nutri Adrenal, as he says 'they might have steroid in them'

or they could be 'placebo' !!!!! Although I do need him to explore the low IGF1

and elevated ALP, so dont want to 'rattle his cage'. If I come off everything,

I risk dipping in health and I 'have' to get back to work asap.

None of my other LFT's are abnormal, and I dont drink escessive amounts of

alcohol. Although 3 years ago after an operation, hours of anaesthesia and some

strong antibiotics - my ALP went up to 890 and all the other LFT's went up as

well. I was investigted for drug induced hepatitis- but this was negative and

all, but the ALP went back to normal and I was dischard with no reason for this.

Thanks

Dawn1

>

> Hi Dawn

>

> You can read about elevated Alkaline phosphates here

> http://labtestsonline.org/understanding/analytes/alp/tab/test - High ALP

> usually means that either the liver has been damaged or a condition causing

> increased bone cell activity is present. If other liver tests such as

> bilirubin <http://labtestsonline.org/understanding/analytes/bilirubin> ,

> aspartate <http://labtestsonline.org/understanding/analytes/ast>

> aminotransferase (AST), or alanine

> <http://labtestsonline.org/understanding/analytes/alt> aminotransfere (ALT)

> are also high, usually the ALP is coming from the liver. If calcium

> <http://labtestsonline.org/understanding/analytes/calcium> and phosphorus

> <http://labtestsonline.org/understanding/analytes/phosphorus> measurements

> are abnormal, usually the ALP is coming from bone. If a GGT

> <http://labtestsonline.org/understanding/analytes/ggt> or 5'-nucleotidase

> is also increased, then the high ALP is likely due to liver

> <http://labtestsonline.org/understanding/conditions/liver-disease> disease.

> If either of these two tests is normal, then the high ALP is likely due to a

> bone condition. Read on...

>

>