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REposting for clarity - please interpret.

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REposting as when read realised it had not kept same format as on my computer

and was confusing!

Have new result for Adrenal stress test and would like to understand what is

happening at moment and so have posted test from 18 months ago for comparison.

>

> Hi all and thank you Sheila for suggesting I repeat my Adrenal Stress Profile

(I have done this via TPA, many thanks). I have the results. I had previously

had this done in June 2010 and now 21st Jan (so 18 months apart). I was quite

ill with severe food allergy/diarrehoea following stress over a long period of

time the first time, this has much improved l although not completely but I

still have lots of problems plus symptoms of Hypothyroid and have never returned

to my former self. I will post both tests for comparison. Are you able to tell

which way I am going? (GENOVA, Ref ranges the same for both tests). I am not

taking any medication apart from HCL/digestive enzymes and Vit C 500mg twice a

day. I recently stopped zinc. No diagnosis yet of hypothyroid (TSH normal

despite high Peroxidase (TPO)

>

> NOW (26/01/12)

>

> SAMPLE 1 post waking 15.1 (12-22 cortisol ref

limits nmol/L)

> SAMPLE 2 (+4-5 hours) 3.0 (low) (5.0-9.0 cortisol ref

limits nmol/L)

> SAMPLE 3 (+4-5 hours) 3.4 (3.0-7.0 cortisol ref

limits nmol/L)

> SAMPLE 4 (prior to sleep) 2.1 (1.0-3.0 cortisol ref

limits nmol/L)

> TOTAL DAILY CORTISOL 23.6 (Range 21-41 nmol/L)

>

> DHEA SAMPLE 2 (am) 0.20 (can't see a ref range

for these)

> DHEA SAMPLE 3 (pm) 0.14 (low)

>

> DHEA Mean 0.17 (Ref range

0.20-0.70 nmol/L)

> DHEA: Cortisol Ratio 0.72 (Ref range 0.6-3.0

nmol/L)

18 MONTHS AGO (16/06/10)

>

SAMPLE 1 post waking 6.3 (low) (12-22 cortisol

ref limits nmol/L)

> SAMPLE 2 (+4-5 hours) 4.2 (low) (5.0-9.0 cortisol ref

limits nmol/L)

> SAMPLE 3 (+4-5 hours) 6.1 (3.0-7.0 cortisol ref

limits nmol/L)

> SAMPLE 4 (prior to sleep) 1.5 (1.0-3.0 cortisol ref

limits nmol/L)

> TOTAL DAILY CORTISOL 18.1 (low) (Range 21-41 nmol/L)

>

> DHEA SAMPLE 2 (am) 0.23 (can't see a ref range

for these)

> DHEA SAMPLE 3 (pm) 0.34

>

> DHEA Mean 0.29 (Ref range

0.20-0.70 nmol/L)

> DHEA: Cortisol Ratio 1.57 (Ref range 0.6-3.0

nmol/L)

SECRETORY IgA 325 micro g /mL (Normal range 118-641) (Optimal range 130-471)

>

>

> I was surprised to see that the DHEA was abnormally low this time but was

normal when I was at my worst 18 months ago when the cortisol seemed worse. The

waking cortisol has now improved although a couple of hours or so later it hits

the deck.

> I also took advice & went to my GP and asked for a referral to Dr Skinner, my

GP agreed but then rang me to say she had changed her mind (due to the GMC

hearing). She offered a referral to a local endocrinologist, I checked he

treats with T3 (rarely) so accepted. She later said she would reconsider a ref

to Dr Skinner later if unsuccessful with local endo!

> I also had lots of other tests from Genova for thyroid, I will post those

separately but seems mainly Peroxidase (will need your help to understand rest

please!)

>

> THANK YOU!

>

>

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Thanks for reposting - yes, the first attempt was quite

confusing.

> NOW (26/01/12)

>

> SAMPLE 1 post waking 15.1 (12-22 cortisol ref limits nmol/L) This has improved considerably - do you feel better in a

morning now?

> SAMPLE 2 (+4-5 hours) 3.0 (low) (5.0-9.0 cortisol ref limits nmol/L) This is dropping further and outside of the bottom of

the range.

> SAMPLE 3 (+4-5 hours) 3.4 (3.0-7.0 cortisol ref limits nmol/L) This too is dropping and is right at the very bottom of

the range.

> SAMPLE 4 (prior to sleep) 2.1 (1.0-3.0 cortisol ref limits nmol/L) - This is too high. You are probably having problems

either getting to sleep or staying asleep. It should be around 1.0.

You could benefit by taking DHEA

25mcgs daily. You would also benefit greatly by taking Nutri Adrenal Extra (see

our FILES section which you can access from the ome Page of this forum). When

there, scroll down the list and open the one entitled 'Discounts on Tests and

Supplements' and then click on the 'Nutri Ltd' document and you will see TPA

members get a discount of 33% on supplements. You should also be taking a

higher dose of vitamin C e.g. 1000mcgs 3 times daily. Vitamin B Complex,

Selenium 200mcgs daily with food.

You must concentrate on boosting

your adrenals.

Start by taking one tablet of

Nutri Adrenal Extra with breakfast, and in 2 to 3 weeks, take another tablet

with lunch (do not take after 1.00p.m.). After another 2 to 3 weeks, if you

still don't feel any different, add another tablet with breakfast. You can

increase this way by taking up to 6 tablets daily, but if this amount is not

helping, you may need a short course of Hydrocortisone.

Have you asked your GP to test

your levels of iron, transferrin saturation%, vitamin B12, vitamin D3, magnesium,

folate, copper and zinc - or are you waiting to ask the endocrinologist to test

these. You need to know whether any of these are low in the range.

Luv - Sheila

> I also took advice & went to my GP and asked for a referral to Dr

Skinner, my GP agreed but then rang me to say she had changed her mind (due to

the GMC hearing). She offered a referral to a local endocrinologist, I checked

he treats with T3 (rarely) so accepted. She later said she would reconsider a

ref to Dr Skinner later if unsuccessful with local endo!

> I also had lots of other tests from Genova for thyroid, I will post those

separately but seems mainly Peroxidase (will need your help to understand rest

please!)

>

> THANK YOU!

>

>

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Thanks Shelia, I appreciate the speed of reply - I know you are particularly

busy at mo.

I am encouraged at the thought of taking something that will boost my energy and

make me feel better. Should I start the DHEA before the endo appt (4-6 weeks

time) in case it confuses any tests he does? Are there any side effects or

dangers with it? Does it actually help to restore the adrenals or is it just to

feel better?

As I have hypophosphatasia as well, which means I don't have the enzyme to deal

with phosphates, my B6 is 434 (15.0-73.0 is normal range). I can't knock off

the phosphate from the pyridoxil, I probably can't utilise B6 in that form

anyway. I was wondering about the Nutri Adrenal Extra as I guess it has B6 in

it. If so, is there another way of doing it?

" Have you asked your GP to test your levels of iron, transferrin saturation%,

> vitamin B12, vitamin D3, magnesium, folate, copper and zinc - or are you

> waiting to ask the endocrinologist to test these. You need to know whether

> any of these are low in the range " .

I have the following results:-

B12 408ng/L (246.0-911) (previously 529 over 1 year ago)

Serum folate 7.8ug/L (5.4-20) (previously 8.9 July 2010)

May 2011 Magnesium 0.98 mmol/L (0.8-1.15)

October 2011 25-Hydroxy Vitamin D 75nmol/L (no ref range given)

Potassium 4.3mmol/L (3.5-5.1)

Serum ferritin is old result (September 2009) 54.2 ug/L (20.0-300.0)

I cant see an iron result

I had an atrocious diet 2008 until about a year or so ago due to intolerance+

I have the results of Total Thyroid screen and awaiting result of urine

T3/screen, will post later.

THANKYOU SHEILA X

>

>

- This is too high. You are probably having problems either getting to sleep or

staying asleep. It should be around 1.0.

>

> You could benefit by taking DHEA 25mcgs daily. You would also benefit

> greatly by taking Nutri Adrenal Extra (see our FILES section which you can

> access from the ome Page of this forum).

[Ed]

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I

can see no problem in you starting the DHEA before your endocrinologists

appointment. Unless you are suffering with 's disease, they are not

likely to suggest doing a short synacthen or ACTH test so not likely to mess

those up. You need to start to look after yourself and it annoys me so much

when we are being left without any treatment/supplements until we see a

specialist, who can take up to 3 months to see us in some cases. Here is a link

where you can read about DHEA and it's uses http://www.independent.co.uk/life-style/health-and-families/health-news/staying-forever-young-565335.html

and also read http://www.well-women.com/support-files/fromthehormonehandbook.pdf

If

you type 'Nutri Adrenal Extra Ingredients into Google', you will find just how

much of the different B vitamins it has

I have the following results:-

B12 408ng/L (246.0-911) (previously 529 over 1 year ago) - you could take 1000mcgs sublingual B12 as a maintenance dose as I

do and this would stop your B12 from falling

Serum folate 7.8ug/L (5.4-20) (previously 8.9 July 2010) - this is still too low and you could try 899mcgs Folic Acid.

Serum ferritin is old result (September 2009) 54.2 ug/L (20.0-300.0) might be an idea to get this retested and also

Haemoglobin,plus transferrin saturation%.

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