Jump to content
RemedySpot.com

Neutropenia

Rate this topic


Guest guest

Recommended Posts

Nick started at 18 months and at our clinic the youngest ever there was 15

months.

Good luck and I hope that you get some answers soon!

Amy, mom to:

, 21 months old. CVID, MSPI, GERD, Asthma.. On claritin, flovent,

xopenex, and IVIG sub Q every two weeks (Carimune NF)

visit Nick's website:

http://www3.caringbridge.org/ne/nicholasb/<http://www3.caringbridge.org/ne/nicho\

lasb/>

Neutropenia

Hi!

We *MAY* be getting somewhere with finding out what is going on with

. His latest blood tests have been helpful!

It looks as though he is going to be tested further for neutropenia.

His neutrophils have been low in all of his bloodwork -- even when

he's not been sick.

I'm so hopeful that we'll get to the bottom of this soon, so we can

start to get him better. This is just so miserable for him (and us!).

Our pediatrician also mentioned IVIG, but said she thought his

immunologist would probably think he was too young. What is the

youngest any of your children have been started on IVIG?

Thanks!

Connie - Mommy to (19 months with low IgG and who knows what

else)

This forum is open to parents and caregivers of children diagnosed with a

Primary Immune Deficiency. Opinions or medical advice stated here are the sole

responsibility of the poster and should not be taken as professional advice.

To unsubscribe -unsubscribegroups (DOT)

To search group archives go to:

/messages<PedP\

ID/messages>

Link to comment
Share on other sites

hey, and how is it going??? it is really getting cold here.. how bout out there?

anyway, conan goes this friday for IVIG and after reading some of the posts , I

am a complete wreck.. Some of the older kids have a horrible time... Just

soooooo stresssed I can't even think... IM me, if you are on line tomorrow

morining..... kathleen

Neutropenia

Hi!

We *MAY* be getting somewhere with finding out what is going on with

. His latest blood tests have been helpful!

It looks as though he is going to be tested further for neutropenia.

His neutrophils have been low in all of his bloodwork -- even when

he's not been sick.

I'm so hopeful that we'll get to the bottom of this soon, so we can

start to get him better. This is just so miserable for him (and us!).

Our pediatrician also mentioned IVIG, but said she thought his

immunologist would probably think he was too young. What is the

youngest any of your children have been started on IVIG?

Thanks!

Connie - Mommy to (19 months with low IgG and who knows what

else)

This forum is open to parents and caregivers of children diagnosed with a

Primary Immune Deficiency. Opinions or medical advice stated here are the sole

responsibility of the poster and should not be taken as professional advice.

To unsubscribe -unsubscribegroups (DOT)

To search group archives go to:

/messages<PedP\

ID/messages></messages<http://groups..c\

om/group//messages>>

Link to comment
Share on other sites

hey, and how is it going??? it is really getting cold here.. how bout out there?

anyway, conan goes this friday for IVIG and after reading some of the posts , I

am a complete wreck.. Some of the older kids have a horrible time... Just

soooooo stresssed I can't even think... IM me, if you are on line tomorrow

morining..... kathleen

Neutropenia

Hi!

We *MAY* be getting somewhere with finding out what is going on with

. His latest blood tests have been helpful!

It looks as though he is going to be tested further for neutropenia.

His neutrophils have been low in all of his bloodwork -- even when

he's not been sick.

I'm so hopeful that we'll get to the bottom of this soon, so we can

start to get him better. This is just so miserable for him (and us!).

Our pediatrician also mentioned IVIG, but said she thought his

immunologist would probably think he was too young. What is the

youngest any of your children have been started on IVIG?

Thanks!

Connie - Mommy to (19 months with low IgG and who knows what

else)

This forum is open to parents and caregivers of children diagnosed with a

Primary Immune Deficiency. Opinions or medical advice stated here are the sole

responsibility of the poster and should not be taken as professional advice.

To unsubscribe -unsubscribegroups (DOT)

To search group archives go to:

/messages<PedP\

ID/messages></messages<http://groups..c\

om/group//messages>>

Link to comment
Share on other sites

  • 2 years later...
Guest guest

I have info on neutropenia www.shwachman.50megs.com

<http://www.shwachman.50megs.com/> click on the neutropenia link to the

left.

Platelets can be high due to infection. my boys have high platelets

(sometimes in the 500s ) and no one is ever concerned. We've been told that

they have to be REALLY high before they become concerned.

Peace be with you,

Pattie

The Will of God will never take you where the Grace of God won't be with

you.

Link to comment
Share on other sites

Guest guest

,

According to my heme, Pneumococcal titers are difficult to interpret. I

think Ursula or Dale will chime in. There are reference ranges to these

titers. I don't see that they are listed, but I think you want a 2-4 fold

increase from a prevaccination titer. Random draws are more difficult to

interpret, but could me that she makes a response and doesn't keep it.

Have you checked out www.primaryimmune.org ?

That is the IDF web site. Not making a protective titer, falls under the

diagnosis of selective antibody deficiency.

lschatz@...

Quoting fourseidels <fourseidels@...>:

> I have been reading your posts for over a year now, trying to get all the

> information I could. I have a 10 yr. old daughter who has struggled with

> immune issues for several years. She also has Eosinophilic Gastroenteritis,

> asthma, and partial seizures.

> She was tested a year ago for immune deficiency, results were poor, they

> gave her a booster and the results improved so they said WAIT and see.

> She continued to be ill quite frequently so we retested a couple of months

> ago and I am not sure what these results mean. Can anyone give me any

> insight?

> Neutrophil count low

> Platelet count high

> IGG at 613 the (bottom of normal)

> 50% serotype response to Pneumococcal vaccine

> #1- 0.7

> #4- 0.5

> #6- 2.1

> #8- 0.8

> #9- 0.7

> #12- 0.2

> #14- 2.9

> #19- 1.4

> #23- 4.4

> #51- 0.7

> All of the above are below or well below normal.

> This concerns me, but I really don't know what I am looking for. Any help

> would be appreciated.

>

>

>

>

> 's Journey

> www.caringbridge.org/visit/jessica16

>

>

>

>

>

>

>

>

Link to comment
Share on other sites

Guest guest

Thank you for sending me your web site. The neutropenia link was helpful.

has had several tooth " buds " that have disappeared, so now she doesn't

have any permanet teeth in those areas. I didn't realize teeth were an issue

until I read your information.

Pattie Curran <catholicmomof3@...> wrote:

I have info on neutropenia www.shwachman.50megs.com

<http://www.shwachman.50megs.com/> click on the neutropenia link to the

left.

Platelets can be high due to infection. my boys have high platelets

(sometimes in the 500s ) and no one is ever concerned. We've been told that

they have to be REALLY high before they become concerned.

Peace be with you,

Pattie

The Will of God will never take you where the Grace of God won't be with

you.

Link to comment
Share on other sites

Guest guest

Thank you for responding. I do have the ranges and the ones I listed are well

below the " normal " range. I will check out the web site you sent.

lmschatz@... wrote:

,

According to my heme, Pneumococcal titers are difficult to interpret. I

think Ursula or Dale will chime in. There are reference ranges to these

titers. I don't see that they are listed, but I think you want a 2-4 fold

increase from a prevaccination titer. Random draws are more difficult to

interpret, but could me that she makes a response and doesn't keep it.

Have you checked out www.primaryimmune.org ?

That is the IDF web site. Not making a protective titer, falls under the

diagnosis of selective antibody deficiency.

lschatz@...

Quoting fourseidels <fourseidels@...>:

> I have been reading your posts for over a year now, trying to get all the

> information I could. I have a 10 yr. old daughter who has struggled with

> immune issues for several years. She also has Eosinophilic Gastroenteritis,

> asthma, and partial seizures.

> She was tested a year ago for immune deficiency, results were poor, they

> gave her a booster and the results improved so they said WAIT and see.

> She continued to be ill quite frequently so we retested a couple of months

> ago and I am not sure what these results mean. Can anyone give me any

> insight?

> Neutrophil count low

> Platelet count high

> IGG at 613 the (bottom of normal)

> 50% serotype response to Pneumococcal vaccine

> #1- 0.7

> #4- 0.5

> #6- 2.1

> #8- 0.8

> #9- 0.7

> #12- 0.2

> #14- 2.9

> #19- 1.4

> #23- 4.4

> #51- 0.7

> All of the above are below or well below normal.

> This concerns me, but I really don't know what I am looking for. Any help

> would be appreciated.

>

>

>

>

> 's Journey

> www.caringbridge.org/visit/jessica16

>

>

>

>

>

>

>

>

Link to comment
Share on other sites

Guest guest

I can send you a PDF article on neutropenia and dental issues. Just let me

know if you'd like to read it & I will zap it to you.

Peace of Christ be with you,

Pattie

" We cannot all do great things, but we can do small things with great love. "

~Mother

Thank you for sending me your web site. The neutropenia link was helpful.

has had several tooth " buds " that have disappeared, so now she

doesn't have any permanet teeth in those areas. I didn't realize teeth were

an issue until I read your information.

Link to comment
Share on other sites

Guest guest

,

also had significant issues with neutropenia. They seem to have

resolved, but he still has episodes of an ANC in the 900 to 1200 range. His

first dx was cyclic neutropenia....

's dx is unclear. We know he has hypogammaglobinemia, not super low, but

dropping numbers with a subclass deficiency. He only made a protective

response to 2 of 12 pneumococcal bugs, and that was after 4 doses of prevnar.

WE know his NK cells showed no function on 3 consecutive lab draws within 6

months which does give him a functional NK cell defect. The last two draws in

the last two years were normal, but they were done during a period of

health....so, the jury is still out on that.

When the numbers are " classically " fitting the diagnosis things are clearer. I

am a firm believer in clinical picture with labs to support...but you cannot

base diagnosis just on numbers. And I believe in quality of life....

Arm yourself with information. Log your lab results....Ask as many questions

as possible...no question is dumb.

www.baxter.com has information as well on newly dx patients and a tutorial

that goes over the immune system.

www.info4pi.org is the jeffrey modell foundation website as well

I am not online much. Work fulltime and parttime and am taking an online

course.

I'll be at work tomorrow until 1. My husband is having surgery and am quite

concerned.

My work email is lschatz@... if you have questions. Email me there and I

can send you my cell # as well.

Hang in there.

S.

Mom to , PID, NOS.

Quoting fourseidels <fourseidels@...>:

> Thank you for responding. I do have the ranges and the ones I listed are well

> below the " normal " range. I will check out the web site you sent.

>

>

>

>

> lmschatz@... wrote:

> ,

>

> According to my heme, Pneumococcal titers are difficult to interpret. I

> think Ursula or Dale will chime in. There are reference ranges to these

> titers. I don't see that they are listed, but I think you want a 2-4 fold

> increase from a prevaccination titer. Random draws are more difficult to

> interpret, but could me that she makes a response and doesn't keep it.

>

> Have you checked out www.primaryimmune.org ?

>

> That is the IDF web site. Not making a protective titer, falls under the

> diagnosis of selective antibody deficiency.

>

>

>

> lschatz@...

>

> Quoting fourseidels <fourseidels@...>:

>

> > I have been reading your posts for over a year now, trying to get all the

> > information I could. I have a 10 yr. old daughter who has struggled with

> > immune issues for several years. She also has Eosinophilic

> Gastroenteritis,

> > asthma, and partial seizures.

> > She was tested a year ago for immune deficiency, results were poor, they

> > gave her a booster and the results improved so they said WAIT and see.

> > She continued to be ill quite frequently so we retested a couple of months

> > ago and I am not sure what these results mean. Can anyone give me any

> > insight?

> > Neutrophil count low

> > Platelet count high

> > IGG at 613 the (bottom of normal)

> > 50% serotype response to Pneumococcal vaccine

> > #1- 0.7

> > #4- 0.5

> > #6- 2.1

> > #8- 0.8

> > #9- 0.7

> > #12- 0.2

> > #14- 2.9

> > #19- 1.4

> > #23- 4.4

> > #51- 0.7

> > All of the above are below or well below normal.

> > This concerns me, but I really don't know what I am looking for. Any help

> > would be appreciated.

> >

> >

> >

> >

> > 's Journey

> > www.caringbridge.org/visit/jessica16

> >

> >

> >

> >

> >

> >

> >

> >

Link to comment
Share on other sites

Guest guest

Pattie,

Thank you for offering to send the articles. I would love to have them. I am

trying to gather all the information that I can.

Pattie Curran <catholicmomof3@...> wrote:

I can send you a PDF article on neutropenia and dental issues. Just

let me

know if you'd like to read it & I will zap it to you.

Peace of Christ be with you,

Pattie

" We cannot all do great things, but we can do small things with great love. "

~Mother

Thank you for sending me your web site. The neutropenia link was helpful.

has had several tooth " buds " that have disappeared, so now she

doesn't have any permanet teeth in those areas. I didn't realize teeth were

an issue until I read your information.

Link to comment
Share on other sites

  • 2 years later...

Our ANC concern point is 750. Macey had cyclic neutropenia when she was

younger. Under a 1000 concerns me but 750 is where we start precautions.

Are his numbers equaling his symptoms and illnesses? 313 is low but if he stays

well then that might be " his " number. Which T-cell test was 454? CD4 or CD8?

Ursula

Mom to (17) and Macey (14,CVID)

http://www.caringbridge.org/visit/maceyholleman

Link to comment
Share on other sites

Our ANC concern point is 750. Macey had cyclic neutropenia when she was

younger. Under a 1000 concerns me but 750 is where we start precautions.

Are his numbers equaling his symptoms and illnesses? 313 is low but if he stays

well then that might be " his " number. Which T-cell test was 454? CD4 or CD8?

Ursula

Mom to (17) and Macey (14,CVID)

http://www.caringbridge.org/visit/maceyholleman

Link to comment
Share on other sites

  • 2 years later...

Does anybody have any expierence of this ?

Despite the name its actually the term for constant Low white blood cells. Which

i have and i believe could be contributing to the fungal infection.

Now i went to my gp today to get a referal to a gastrologist, but i thought i

would get a copy of my patient notes and on them it says i have neutropenia. But

noone has ever dicussed this with me before so i knew very little about it. I

asked my gp is there any way i could raise my white blood cells, she says no

there is not.

My first google search brings up these treatments

-antibiotic and/or antifungal medications to help fight infections;

-administration of white blood cells growth factors (such as recombinant

granulocyte colony-stimulating factor (G-CSF, filgrastim) in some cases of

severe neutropenia; granulocyte transfusions; or

-corticosteroid therapy or intravenous immune globulin for some cases of

immune-mediated neutropenia.

http://www.medicinenet.com/neutropenia/page3.htm#treated

Im really angry if im honest how can a doctor tell me there is no treatment?

Also my FT3 was 29 like Nicks as i mistakenly took my T3 right before before the

test as i thought we had agreed to leave my thyroid labs until my next

appointment. I try to tell her that took my T3 1 hour before the test by

accident, then she says that it does not matter as you take a 24 hour dose. She

thinks T4 is the same as T3 we have already had this argument before. :((

What would you advise about my Neutropenia? I have my endo appointment on monday

should i just discuss it there, or would it be wise to make another gp

appointment?

Thanks and i dont knoww what i would do without this group.

Steve

Link to comment
Share on other sites

Hi Steve

i'm not too bad , some days are better than others. you know how it is.

thanks for asking

chris

>

> Indeed Chris

>

> How are you health wise at the minute, not seen you posting all that much

recently ?

Link to comment
Share on other sites

hi steve

just a thought but what is your copper like ...i have read that low (or

bio-unavailable) copper can have a HUGE impact on candida ...i believe i have

also read that the candida copper connection can be a cause of low white blood

cells ...unfortunately i cannot re-find a reference to back that up (sorry).

have you had copper levels tested? what about ceruloplasmin (the copper

transporter) ...copper, zinc and iron are the three corners of a triangle and

they need to be in proper ratio to one another ...i seem to recall you have had

some iron issues too?

http://www.greatplainslaboratory.com/home/eng/ceruloplasmin.asp

trish

>

> Does anybody have any expierence of this ?

>

> Despite the name its actually the term for constant Low white blood cells.

Which i have and i believe could be contributing to the fungal infection.

Link to comment
Share on other sites

Simply Steve, Neutropenia is caused through some form of

infection - somewhere in the body, but it doesn't tell you exactly where.

Identify the infection, treat it to the best of your ability, once treated, the

white cells will increase and your neutropenia will likely disappear. What

level of white cells have you and what is the reference range?

Have you no chance of running a mile from this idiotic doctor

who doesn't know the difference between T4 and T3 - have a word with your local

Primary Care Trust who will find you somebody else in your area - and somebody

who probably actually cares about their patients.

Luv - Sheila

Despite the name its actually the term for constant Low white blood cells.

Which i have and i believe could be contributing to the fungal infection.

Now i went to my gp today to get a referal to a gastrologist, but i thought i

would get a copy of my patient notes and on them it says i have neutropenia.

But noone has ever dicussed this with me before so i knew very little about it.

I asked my gp is there any way i could raise my white blood cells, she says no

there is not.

http://www.medicinenet.com/neutropenia/page3.htm#treated

Im really angry if im honest how can a doctor tell me there is no treatment?

Link to comment
Share on other sites

I spoke to my endo about it yday and he said it was nothing to worry about, but

we did have quite a big disuccion about it. He said as mine are not low on every

single test some of them are in range but near bottom that it was acceptale and

that my body was just fighting a " hidden " virus as the time of the blood test. -

How much of that is true i dont know.

Now that i am off HC/Florinef he had no objection for me getting a full blood

count this week and then in 3 weeks time - To check if they both come back low

or within range.

Steve

>

> Thanks Sheila, I have read this but my GP is still ignorant and thinks my test

results are OK! Maybe I will print off a copy and give it to him!

Link to comment
Share on other sites

Show him everything that you can Anita, and if he fails to take

any notice of what his patient is telling him, find another doctor, but not

before telling the Head of Practice that you have lost all faith in this

particular doctor. I have found that there are many doctors who don't know

everything, which is natural, but rather than do a bit of research, they will

throw it back on the patient trying to make them believe there is nothing wrong

with them - and it is up to us to stop this happening anymore.

Luv - Sheila

Thanks Sheila, I have read this but my GP is

still ignorant and thinks my test results are OK! Maybe I will print off a copy

and give it to him!

I started taking the ferrous fumarate and feel better!! The dizziness is much

less, my head is less foggy, I'm more alert and awake, get going easier and

quicker in the morning, have more energy! And this is after 4 days of taking

it! Started the B12 nuggets too.

Link to comment
Share on other sites

Hi Steve,

My levels are very similar to yours and my WBC has been low like this for the

past 7 or 8 years following Epstein Barr Virus.

I have suffered with lots of infections over the years that are slow to clear

up.

I would definately insist on being referred to a haematologist.

I was and they gave me iron ifusions for my low iron and they did talk about

doing a bone marrow biopsy to test my cells further.

I was then passed on to a gastro to check out possible causes of my ongoing

anemia. All the gastro tests came back clear (this took years on NHS!) and I am

going back to see a haematologist tomorrow.

I'm really exhausted tonight, but I will report back more tomorrow.

Take care,

x

>

> Yeh im thinking its because my body is fighting the candida infection and

failing would this fit low WBC ?

>

> My actual results are

> lympocyte count 0.6 (1.5-40.)

> WBC 3.0 (4.0-11.0)

>

Link to comment
Share on other sites

Join the conversation

You are posting as a guest. If you have an account, sign in now to post with your account.
Note: Your post will require moderator approval before it will be visible.

Guest
Reply to this topic...

×   Pasted as rich text.   Paste as plain text instead

  Only 75 emoji are allowed.

×   Your link has been automatically embedded.   Display as a link instead

×   Your previous content has been restored.   Clear editor

×   You cannot paste images directly. Upload or insert images from URL.

Loading...
×
×
  • Create New...