Block and Replace

[Guest guest]

There's an oddity in the online forum (I think)

Twice, in the context of hypOthyroidism the doc refers to Block and Replace as

meaning take enough T4

snippet 1

You need to " block " your bodies own supply of thyroxine (by giving enough T4)

and " replace " it completely otherwise your next blood tests will be meaningless

& confusing.)

snippet 2

It should now be standard practice to " block and replace " . This means using a

large enough dose of T4 to block the bodies own production and provide enough

for the body.

Now I'm certain that what is normally meant by Block and Replace is for

hypothyroidism, ie Block with carbimzole (or whatever) and Replace witn T4 (or

whatever).

Has anyone here come across this notion for hypo. Is it factually correct?

Steve

[Guest guest]

On Fri, 10 Feb 2012 13:27:45 -0000, you wrote:

>Now I'm certain that what is normally meant by Block and Replace is for

hypothyroidism, ie Block with carbimzole (or whatever) and Replace witn T4 (or

whatever).

>

>Has anyone here come across this notion for hypo. Is it factually correct?

Agreed, block and replace is for hypER

He may have been trying to refer to a " full replacement dose " , ie

enough T3 or natural to fully suppress TSH and shut your own thyroid

down.

This means a TSH of around 0.01 and if you do it with T4 only you will

almost certainly end up producing too much RT3.

If your " set point " is wrong, ie TSH is regulating to the wrong level

of FT3, then a full replacement dose is necessary to get the FT3 up.

Dosing for TSH is pretty useless and totally useless in this

circumstance

Nick

[Guest guest]

Hi my only thought on this is are they talking about patients with thyroid

cancer? This means stopping the thyroid producing anything {Block] and [replace]

with synthetic .