Re: Hubby's TSH/bloods and Cholesterol results - advice please? BUMP

[Guest guest]

Thank you for the comments and help so far. No one has commented on the results

though. I wonder if someone could comment on those too please?

Many thanks,

>

> Can anyone help please?

>

> Since realising that I have an autoimmune thyroid problem I have been more

conscious of the problem in other people! I hadn't realised that right under my

nose not only has my aged father got a problem but also my husband.

>

> I looked back through all of my husband's blood results which oddly enough he

had always asked for but filed away. He has always had abnormal results for

several things but I took note of his TSH:-

> 2005 - 3.96 (0.4-4.0)

> 18/01/2010 - TSH 4.79 (0.35-5.5)

> 19/07/2011 - TSH 5.36 - I posted this one here and was advised he is

definately hypothyroid, therefore got his GP to repeat again:

> 19/03/12 - TSH 6.99 mu/L (0.35-5.5)

>

> So you can see the trend is TSH rising - have to see his GP on Friday for

these result officially!

>

> His worst symptoms are tiredness and unrefreshing sleep ( & lots of other

problems)

>

> Other blood results were:

> Cholesterol 7.0 mmol/L (3.0-5.0) this is the highest its been.

>

> Now the reason his GP wants to see him again is because he has not been taking

Persantin, a drug to prevent clots as he has small vessel disease and a history

of mini-strokes. We spent an HOUR (honest!) with this doctor last week as he

was trying to persuade him to take this drug and we discussed risks. Also he

said he needed to see him again to discuss statins (he has resisted this so

far).

>

> Meanwhile I asked for all of the minerals you mention here but he refused some

of them. It appears that even though the TSH is raised officially now, he will

want to retest in a month. He spent ages explaining away the trend of TSH last

week to improved reagents at different labs etc.

>

> Could you comment re other results please?

> T4 12.0 pmol/L (10.0-19.8)

> Haemoglobin 13.8g/dL (13.3-17.3)

> Total white blood count 4.5 (3.8-11.0)

> Red blood cell count 4.51 (4.5-6.0)

> Haematocrit 0.41 (0.4-0.5)

> Platelet count 210 (150-400.0)

>

> Neutrophil count 2.7 (2.0-7.5)

> Lymphocyte count below range 1.2 (1.5-4.0)

> monocyte 0.4 (0.20-0.8)

> Eosinophil count 0.2 (0.0-0.4)

> Basophil 0.0 (0.0-0.5)

> promyelocyte count (0.01 (0.0-0.5)

>

> vit B12 520ng/L (246-911)

> folate 10.8 (5.4-20.0)

> ferritin 92.6ug/L (20.0-300.0)

>

> Previously he checked his Salivary Cortisol Stress Test on 26/01/2012 results

seem ok to me but maybe someone could confirm that.

>

> Sample 1 17 (12-22)

> sample 2 7.4 9 (5.0-9.0)

> Sample 3 4.0 (3.0-7.0)

> Sample 4 1.8 (1.0-3.0)

>

> Total Daily Cortisol 30.2 (21 -41 nmol/L)

> DHEA: Cortisol 0.45

> DHEA Mean 0.14 (0.10-0.5)

> DHEA Cortisol 0.45 (0.4-2.0)

>

> He has always been very fit and active but is noticeably going down hill

rapidly.

>

> Thank you if you managed to get to the end of this and for any advise you can

offer.

>

> Best wishes to all,

> x

>

[Guest guest]

> Could you comment re other results please?

> T4 12.0 pmol/L (10.0-19.8)

> Haemoglobin 13.8g/dL (13.3-17.3)

> Total white blood count 4.5 (3.8-11.0)

> Red blood cell count 4.51 (4.5-6.0)

> Haematocrit 0.41 (0.4-0.5)

> Platelet count 210 (150-400.0)

> Neutrophil count 2.7 (2.0-7.5)

> Lymphocyte count below range 1.2 (1.5-4.0)

> monocyte 0.4 (0.20-0.8)

> Eosinophil count 0.2 (0.0-0.4)

> Basophil 0.0 (0.0-0.5)

> promyelocyte count (0.01 (0.0-0.5)

All these red cell figures look low - as does the T4 level ...

Iron deficiency anemia may be a problem and will certainly make your spouse

tired. A low Red Cell count, low Haemoglobin and low Haematocrit, all point to

poor oxygen-carrying capacity of the blood.

Increasing Hypothyroidism will exaggerate this decline in energy levels (as

shown by low T4 and increasing TSH).

A question to ask is ~ why is there a hint of excessive haemolysis implied by

the low iron as haemoglobin ?

Does your spouse have a bronze colouration to his arms (indicates

Haemochromatosis)?

best wishes

Bob

>

> Thank you for the comments and help so far. No one has commented on the

results though. I wonder if someone could comment on those too please?

> Many thanks,

>

>

> --- In thyroid treatment , " julianadivarna " <

[Guest guest]

Hi Bob,

many thanks for looking at these results. We appreciate very much such valuable

help and advice, thank you.

I have no knowledge about haemochromatosis at all. I have looked it up this

afternoon but don't understand why his Ferritin would be low and not high,

wouldnt it be high if he had haemochromatosis? His GP says he is not anaemic!

His his arms are brown but look normal to me but his face is rather sallow and

looks slightly yellowy underneath the brown. Is there a diagnostic test for

this?

ie:-

vit B12 520ng/L (246-911)

folate 10.8 (5.4-20.0)

ferritin 92.6ug/L (20.0-300.0)

His his arms are brown but look normal to me but his face is rather sallow and

looks slightly yellowy underneath the brown. Is there a diagnostic test for

this?

We are seeing his GP again on Friday evening, so far he is unwilling to treat

the hypothyroidism (TSH 6.99) but we hope he will weaken. He is more interested

in his raised cholesterol at he moment and has told him to walk 30 minutes twice

a day to see if relieving stress will help him to feel better.

I would like to pursue the possibility of heamochromatosis - I have just bought

a cast iron pan to try & raise both of our iron levels but if he has this

condition I gather we have to keep iron low!

thanks Bob

Best wishes,

>

>

> > Could you comment re other results please?

> > T4 12.0 pmol/L (10.0-19.8)

> > Haemoglobin 13.8g/dL (13.3-17.3)

> > Total white blood count 4.5 (3.8-11.0)

> > Red blood cell count 4.51 (4.5-6.0)

> > Haematocrit 0.41 (0.4-0.5)

> > Platelet count 210 (150-400.0)

>

> > Neutrophil count 2.7 (2.0-7.5)

> > Lymphocyte count below range 1.2 (1.5-4.0)

> > monocyte 0.4 (0.20-0.8)

> > Eosinophil count 0.2 (0.0-0.4)

> > Basophil 0.0 (0.0-0.5)

> > promyelocyte count (0.01 (0.0-0.5)

>

> All these red cell figures look low - as does the T4 level ...

>

> Iron deficiency anemia may be a problem and will certainly make your spouse

tired. A low Red Cell count, low Haemoglobin and low Haematocrit, all point to

poor oxygen-carrying capacity of the blood.

>

> Increasing Hypothyroidism will exaggerate this decline in energy levels (as

shown by low T4 and increasing TSH).

>

> A question to ask is ~ why is there a hint of excessive haemolysis implied by

the low iron as haemoglobin ?

>

> Does your spouse have a bronze colouration to his arms (indicates

Haemochromatosis)?

>

> best wishes

> Bob

[Guest guest]

Hi ,

These two sources may help:-

Dipyridamole for preventing stroke and other vascular events in patients with

vascular disease

http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD001820.pub3/full

Stroke management

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152174/?tool=pubmed

If the iron is being hidden away in cells, it may not show up in a blood test

for haemochromatosis. Perhaps, is your husband's colour associated with an

ian condition (low cortisol) where skin folds/scars tend to show up a

darker colour than normal?

and yes ferritin may be higher if this is haemochromatosis

Best wishes

Bob

>

> Hi Bob,

> many thanks for looking at these results. We appreciate very much such

valuable help and advice, thank you.

>

> I have no knowledge about haemochromatosis at all. I have looked it up this

afternoon but don't understand why his Ferritin would be low and not high,

wouldnt it be high if he had haemochromatosis? His GP says he is not anaemic!

>

> His his arms are brown but look normal to me but his face is rather sallow and

looks slightly yellowy underneath the brown. Is there a diagnostic test for

this?

>

> ie:-

> vit B12 520ng/L (246-911)

> folate 10.8 (5.4-20.0)

> ferritin 92.6ug/L (20.0-300.0)

>

> His his arms are brown but look normal to me but his face is rather sallow and

looks slightly yellowy underneath the brown. Is there a diagnostic test for

this?

>

> We are seeing his GP again on Friday evening, so far he is unwilling to treat

the hypothyroidism (TSH 6.99) but we hope he will weaken. He is more interested

in his raised cholesterol at he moment and has told him to walk 30 minutes twice

a day to see if relieving stress will help him to feel better.

>

> I would like to pursue the possibility of heamochromatosis - I have just

bought a cast iron pan to try & raise both of our iron levels but if he has this

condition I gather we have to keep iron low!

>

> thanks Bob

> Best wishes,

>