Re: Hubby's TSH/bloods and Cholesterol results - advice please?

[Guest guest]

,

I'm sure it will tell you in the files, but one of the ways they used to

diagnose people with hypothyroidism, was by looking at the cholesterol levels.

They rise with hypo and statins are contra indicated in people with

hypothyroidism.

They gave up diagnosing this way, and using common sense when someone invented

the holy miracle of the TSH test! (have a look on you tube)..

Make sure the doctor tests your husbanda antibodies..... the rising tsh

suggests there may be a problem.

The 'rule' seems to be: tsh over 5 and antibodies are given meds, If no

antibodies, people are left until tsh reaches 10.....

x

>

> Can anyone help please?

>

[Guest guest]

Hi ,

Try this link:

http://jcem.endojournals.org/content/97/2/326.abstract

Thyroid hormone has multiple effects on the regulation of lipid synthesis,

absorption, and metabolism. Studies consistently demonstrate elevated levels of

serum total cholesterol, low-density lipoprotein cholesterol (LDL-C),

apolipoprotein B, lipoprotein(a), and possibly triglycerides in individuals with

overt hypothyroidism, all of which are reversible with levothyroxine therapy.

and also this one:

http://jcem.endojournals.org/content/92/2/608.abstract?sid=9b9f01bb-5f97-4d1e-8c\

a4-16b999c8d3b6

Context: Recently, non-high-density lipoprotein cholesterol (non-HDL-C), a

measure of total cholesterol minus HDL-C, has emerged as a predictor of

cardiovascular disease.

Objective: We evaluated the effect of L-T4 replacement on non-HDL-C levels in

patients with primary hypothyroidism.

Methods: Thirteen patients with overt hypothyroidism and 26 patients with

subclinical hypothyroidism participated in the study. The lipid profiles,

including non-HDL-C, were measured in patients with hypothyroidism before and 3

months after L-T4 replacement was started.

Results: After L-T4 replacement, the serum concentrations of all lipoproteins,

exclusive of lipoprotein (a) [Lp(a)], were significantly decreased in patients

with overt hypothyroidism.

The Journal of clinical endocrinology is a great place to find research to back

up what we know to be true sometimes.

Regards

Nadia

>

> Can anyone help please?

> I plan now to try and find something about the effects of thyroid hormones on

cholesterol so that his GP will agree to treat him for the hypothyroidism and

see what effect that has before giving statins or blood thinning agents (he

plans to give simvastatin and Clopidogrel). Bearing in mind he not only has

raised cholesterol but also small vessel disease with history of ministrokes).

He also has a history of polymyalgia rheumatica but was treated successfully

with steroids at the time. He takes blood pressure drugs and a allopurinol for

gout prevention. He has always been very fit and active but is noticeably going

down hill rapidly.

>

> Thank you if you managed to get to the end of this and for any advise you can

offer.

>

> Best wishes to all,

> x

>