Re: Fw: Anti-Cancer research missing from Federal Archive.

[Guest guest]

I would like to know why Joyce was banned from this group!!! I enjoyed what

she had to offer and can not understand when someone is willing to offer so

much why we would want to bann them.

I don't remember her attacking folks character or calling people names, and

yet she is not allowed to post anymore. Maybe someone can shed alittle light

on the matter for me. There are not that many folks that contribute, and yet

when someone like Joyce dedicates their time to share we find a reason to

boot them off. It seems we fear those that want to talk about God and yet we

have no problem letting the devil slip in the back door.

So could someone please enlighten me and tell me why Joyce is no longer

allowed?

Debbie

Re: Anti-Cancer research missing from Federal Archive.

>

>

> >

> > " THE PLASMA MEMBRANE AS A TARGET IN ANTICANCER CHEMOTHERAPY " .

> >

> > This is well known in immunology. The MEMBRANE is the key to

> > successful IMMUNITY. This is why we need Essential Fatty Acids--it is

> > used to make part of the Cell Membrane. I'm afraid the " fat scare " has

> > caused many people to become sick, and the cause is lack of Essential

> > Fatty Acids for healthy Membranes. The medical profession has scared

> > people from taking the Vital Oils and Fats needed for life. The

> > IMMUNE SYSTEM is a Communication System, and the greater part of

> > COMMUNICATION happens at the MEMBRANE.

> >

> > As I recall, STRESS can cause the body to produce bad

> > nitrogen-containing compounds which cause normal cells to transform

> > into cancer cells. These nitrogen compounds damage the Cell Membrane,

> > which is part of the reason for carcinogenesis. Thioproline will help

> > render some of these bad chemicals harmless. People who harbor

> > unforgiveness and resentments produce bad chemicals by the brain,

> > which interact with the MEMBRANE of Immune Cells.

> >

> > There is a BRAIN-IMMUNE-HORMONE interaction which may control how sick

> > or healthy you are. God says to love, forgive, and bless others, and

> > to think thoughts which are pure, good, holy, true, of good report,

> > etc. These thoughts produce good chemicals in the brain, which also

> > interact with the MEMBRANE of Immune Cells, strengthening the Immune

> > System and the Body.

> >

> > There seems to be a dedicated effort to hide from the public the

> > things that will keep people healthy. God's Laws for HEALTH is one.

> > His laws tell us how to think to keep healthy, and which foods to eat

> > (e.g. raw fruits, vegetables, seeds, etc.) to keep us from getting

> > diseases.

> >

> > Joy

> > --------------------------------------------------------------------

> >

> >

> > >

> >

> > >

> > >September 10, 2000

> > >

> > > " The only good is knowledge and the only evil is ignorance. "

Socrates

> > >

> > >My research describes treatments for Cancer, HIV/AIDS, Alcohol Abuse,

Lou

> Gehrig's Disease (ALS), Macular Degeneration & Chronic Myelogenous

Leukemia

> (CML).

> > >

> > >Representative J. Visclosky

> > >2313 Rayburn Building

> > >Washington, D.C. 20515-1401

> > >

> > >Dear Congressman Visclosky,

> > >

> > >The report of one of the most astounding anti-Cancer discoveries of the

> 20th Century is missing from an official archive of the United States

> Government.

> > >

> > >If you type www.ncbi.nlm.nih.gov/pubmed into The Internet you will see

> that this information first appears -

> > >

> > > " PubMed is the National Library of Medicine's search service that

> provides access to over 11 million citations in MEDLINE, PreMEDLINE, and

> other related databases, with links to participating online journals. "

> > >

> > >Congressman Visclosky, the abstract of the March, 1979 article written

by

> Gosalvez does not appear in 'MedLine'; the title of the article is,

> " THE PLASMA MEMBRANE AS A TARGET IN ANTICANCER CHEMOTHERAPY " .

> > >

> > >In this article Gosalvez concluded, from his laboratory research,

> that the chemical, Thiazolidine-4-carboxylic acid (Thioproline),

" .....could

> represent the first non-cytotoxic anticancer agent which has the plasma

> membrane as target. "

> > >

> > >Indeed, a few months later in the latter half of 1979 a clinical trial

> conducted by Gosalvez and his colleague, Brugarolas,

revealed

> this result after Thioproline had been administered to Cancer patients in

> Spain -

> > >

> > > " .....Histological studies showed involution and transformation into

> low-grade malignancies and disappearance of evidence of cancer. "

> > >

> > >(An abstract of this research does appear in MedLine - UI:80098547.)

> > >

> > >Congressman Visclosky, the March, 1979 research of Gosalvez was

> funded by the U.S. National Cancer Institute under Contract NO1-CM-53792.

> > >

> > >Did someone at the U.S. National Cancer Institute determine that the

> result of the March, 1979 research was not important enough to be included

> in MedLine?

> > >

> > >Congressman Visclosky, could Dr. Varmus afford us an explanation of

this

> omission and tell us what he is prepared to do to correct this oversight?

> > >

> > >Congressman Visclosky, I was somewhat surprised to see that the U.S.

> National Cancer Institute did not explore further the results of the

> Gosalvez/Brugarolas research with additional clinical trials upon human

> beings. Instead, this agency was content to fund research upon rats and

> mice.

> > >

> > >Congressman Visclosky, included in this envelope is a copy of my

November

> 7, 1999 letter to Dr. Varmus; in that letter is this passage:

> > >

> > >Text -

> > >

> > >Dr. Varmus, I see that after the Spanish research was published the

> National Cancer Institute supported in part (grant CA-24543) and contract

> No1-CM-97278, Division of Cancer Treatment, Study Number 35,

" Pharmacologic

> and Toxicologic Evaluation of Thioproline: A Proposed Nontoxic Inducer of

> Reverse Transformation " , 'Cancer Treatment Reports', Vol. 64, No. 8-9,

> August/September 1980, pages 837-844. Its summary states:

> > >

> > > " The ability of thioproline to act as a nontoxic inducer of reverse

> transformation was examined. Thioproline was unable to effect reproducibly

> morphologic changes characteristic of the reverse transformed state in

HeLa,

> WI-38VA13, C1300 neuroblastoma, and CHO-K1 cell lines. Reversal of

> transformed cells with dibutyryl cyclic AMP was, however, readily

> demonstated in both the CHO-K1 and C1300 cell lines. Thioproline produced

> severe, life threatening CNS toxicity in both mice and rats at levels far

> below those previously reported to be without any toxic effects. We

conclude

> that not only is thioproline incapable of producing a reversal on the

> transformed state in HeLa and other cell lines in vitro, it is also a

> compound that must be described as a strongly CNS toxic agent. "

> > >

> > >Dr. Varmus, I am disappointed to see that the National Cancer Institute

> did not conduct a clinical trial to see what effect thioproline might have

> upon human beings, as was done in Spain in 1979.

> > >

> > >Dr. Varmus, I assume the National Cancer Institute (NCI) conducted

> meetings to compare and contrast the research which I have thus far cited.

> Am I over-looking any other important studies which the NCI may have taken

> into consideration?

> > >

> > >Dr. Varmus, are minutes of those meetings available which could be made

> public to the American populace?

> > >

> > >Dr. Varmus, on what basis did the NCI decide to discontinue efforts to

> investigate the possibilities of the Brugarolas/Gosalvez research? What

was

> the key factor which abnegated interest in Thiazolidine-4-carboxylic acid

> (Thioproline) as an anti-cancer agent? Could it have been its toxicity?

> > >

> > >End of Text -

> > >

> > >Congressman Visclosky, I hope that Dr. Varmus will afford, at least to

> you, a response to the aforementioned passage.

> > >

> > >Congressman Visclosky, in the 'Dr. Varmus' letter I also state:

> > >

> > > " Dr. Varmus, since November, 1997, I have been proposing the

combination

> of 'mega-doses' of Thiazolidine-4-carboxylic acid and vitamin C and 'above

> average' amounts of magnesium, zinc and manganese as an anti-cancer agent.

> > >

> > >I really would like to see some resolution to this matter. "

> > >

> > >Congressman Visclosky, after reviewing the data delineated in the Post

> Script of this letter, I hope that Dr. Varmus will see the compelling need

> to repeat the 1979 Spanish clinical trial.

> > >

> > >To repeat, with Thioproline, alone, this result was achieved in 1979 -

> > >

> > > " .....disappearance of evidence of cancer. "

> > >

> > >My research has revealed a most unusual fact of nature - vitamin C

> neutralizes the toxicity of Thioproline - thus - Cancer patients could

> swallow 'mega-doses' of Thioproline if they also swallowed, at the same

> time, 'mega-doses' of vitamin C.

> > >

> > >Yours truly, , jsr1936@..., P.O. Box H,

> Hobart, IN 46342, (219) 763-1933

> > >

> > >Copies to -

> > >

> > >Donna E. Shalala, Ph.D., Secretary of Health and Human Services,

> Washington, D.C.

> > >Harold E. Varmus, M.D., Director, National Institutes of Health (NIH),

> Bethesda, land

> > > Klausner, M.D., Director, National Cancer Institute, (NCI),

> Bethesda, land

> > >Lake/Porter County Medical Society, Merrillville, Indiana

> > >

> > >Post Script -

> > >

> > >The following data might prove beneficial to anyone troubled by Cancer,

> HIV/AIDS, Alcohol Abuse, Lou Gehrig's Disease (ALS), Macular Degeneration

&

> Chronic Myelogenous Leukemia (CML).

> > >

> > >More details can be found in my website, The Cure for Cancer?

> www.datadepo.com/cures for cancer/tac-cure.htm .

> > >

> > >Sometimes I will refer to 'MedLine'; this is the procedure to follow -

> access www.ncbi.nlm.nih.gov/pubmed, type in the Unique Identifier (UI)

> number, then 'click on' to the name cited to 'bring up' the full abstract.

> > >

> > >1. Cancer - Why is the following information missing from the National

> Archive, 'MedLine'?

> > >

> > >There are over 11 million citations in 'MedLine'.

> > >

> > >MedLine is The Internet resource of the National Library of Medicine.

> > >

> > > Gosalvez wrote 4 articles in 1979 which are cited in MedLine -

> > >

> > >1. January, 1979 - " Inhibition of sodium-potassium-activated adenosine

> 5'-triphosphatase and ion transport by adriamycin. "

> > >2. February, 1979 - " A possible pathogenic mechanism for the induction

of

> rotenone tumours. "

> > >3. February, 1979 - " Restoration of 'contact inhibition' in tumour

cells

> in tissue culture by treatment with thiazolidine-4-carboxylic acid. "

> > >4. May, 1979 - " Early clinical trial with quelamycin. "

> > >

> > >However, Gosalvez wrote a 5th article in 1979, and it is not

cited

> in MedLine.

> > >

> > >A little bit of history - The U.S. National Cancer Institute under

> Contract NO1-CM-53792 had funded the Cancer research of Gosalvez; at

> the time he was a researcher at the Bioquimica Experimental, Clinica

Puerta

> de Hierro, Madrid-35, Spain.

> > >

> > >The result of Gosalvez' research was published in the March,

1979,

> issue of the 'Proceedings of the American Association for Cancer

Research',

> Volume 20, page 17.

> > >

> > >These words of Gosalvez appear in 'AACR ABSTRACTS, 1979', No. 68

> (All bold face emphasis is mine.):

> > >

> > > " .....The screening included the test of compounds: 1) in cell capping

of

> immuno-globulins; 2) in the differentiation of the mold Dictyostelium

> discoideum and 3) in the restoration of contact inhibition of Hela cells

in

> tissue culture. One compound out of 500, thiazolidine-4-carboxylic acid

> (j.s.r. - Thioproline), was active in the three screening steps and was

able

> to restore contact inhibition in Hela cells in tissue culture. This

compound

> has been brought to the clinics in Spain in patients of advanced

metastasic

> progressing cancer, under the name of Norgamem. Norgamem could represent

the

> first non-cytotoxic anticancer agent which has the plasma membrane as

> target. "

> > >

> > >To double check and confirm the fact that this 5th article of

> Gosalvez is not contained in MedLine, type in the title of the article,

'THE

> PLASMA MEMBRANE AS A TARGET IN ANTICANCER CHEMOTHERAPY', into 'Search

PubMed

> for', click on to 'Go', and these words will appear - " No items found " .

> > >

> > >In fact, none of the Divisions of MedLine (PubMed, Protein, Nucleotide,

> Structure, Genome, Popset, Taxonomy) contain a reference to this 5th

article

> of Gosalvez which was published in March, 1979.

> > >

> > >The subsequent clinical trial in Spain, in the latter half of 1979,

> revealed these results after Thioproline had been administered to human

> beings with Cancer -

> > >

> > > " .....Definite signs of activity were observed.....in other solid

> tumours, such as breast, renal, ovary, thyroid, and parotid cancer. "

> > >

> > > " .....Histological studies showed involution and transformation into

> low-grade malignancies and disappearance of evidence of cancer. "

> > >

> > >The aforementioned words appear in one of the world's foremost medical

> journals, 'The Lancet', January 12, 1980, pages 68 to 70.

> > >

> > >2. Cancer - What do I think of the scientific/medical research which

> occurred between 1980 and 1983 relative to the result of the 1979 Spanish

> clinical trial - " .....disappearance of evidence of cancer. "

> > >

> > >Refer to the 'Dr. Varmus' letter; this letter chronicles the puny,

paltry

> effort put forth by the scientific community from 1980 to 1983 to take

> advantage of this marvelous result. The medical community settled for

> scanty, skimpy research in reaching its decision to abandon interest in

> Thioproline as a possible Cancer cure.

> > >

> > >As a result of this feeble, futile, feckless, abortive research effort,

a

> negative light was cast upon Thioproline which the world has been doomed

to

> live with throughout the past two decades.

> > >

> > >Note these poignant words of Gosalvez in the 'Dr. Varmus' letter:

> > >

> > > " .....However, reports of our later work given at scientific meetings

or

> in the pipeline, confirm that thioproline does induce reverse

transformation

> and that the whole concept, despite its complexities, is promising. "

> > >

> > >3. Cancer - Would it be difficult to repeat the 1979 Spanish clinical

> trial?

> > >

> > >Not at all! The parameters of the 1979 trial were fairly simple (page

68,

> 'The Lancet', January 12, 1980) -

> > >

> > > " The criteria used in the selection of patients were: pathological

> diagnosis of advanced cancer resistant to treatment; physical condition

> allowing outpatient care; measurable tumour for evaluation of the

response;

> no other cancer treatment in the 4 weeks before, or during thioproline

> treatment; and informed consent by patients. "

> > >

> > > " Clinical assessment included history and examination, measurement

of

> tumours, chest X-ray, ECG, complete blood counts, liver profile, and urine

> analysis. These assessments were made before treatment began, and every

1-3

> weeks during treatment. "

> > >

> > >In the 1979 trial some patients were injected with Thioproline, 20 to

40

> mg/kg. daily, and some patients swallowed it, 5 mg/kg. daily.

> > >

> > >I have discovered a unique fact of nature - vitamin C affords

phenomenal

> protection against the toxicity of Thioproline.

> > >

> > >Consequently, a new clinical trial could determine what the effect

would

> be on Cancer patients if they swallowed ' mega-doses' of Thioproline and

> vitamin C; in my opinion, the 'mega-dose' amount of Thioproline could be

as

> high as 40 mg/kg. daily (maybe more!).

> > >

> > >This is not to say that the patients would have to begin immediately

with

> a 40 mg/kg. daily dosage of Thioproline -

> > >

> > >On day 1 the patients would swallow 10 mg/kg. of Thioproline; if no

> problems develop -

> > >On day 2 the patients would swallow 15 mg/kg. of Thioproline; if no

> problems develop -

> > >On day 3 the patients would swallow 20 mg/kg. of Thioproline; if no

> problems develop -

> > >On day 4 the patients would swallow 25 mg/kg. of Thioproline; if no

> problems develop -

> > >On day 5 the patients would swallow 30 mg/kg. of Thioproline; if no

> problems develop -

> > >On day 6 the patients would swallow 35 mg/kg. of Thioproline; if no

> problems develop -

> > >On day 7 the patients would swallow 40 mg/kg. of Thioproline.

> > >

> > >Thus, within a week, the administrators of the Cancer clinical trial

> could determine whether patients could safely swallow 40 mg/kg. daily of

> Thioproline (along with their vitamin C).

> > >

> > >Further details can be found on pages 7 to 9 (left hand side

pagination)

> of The Cure for Cancer?. My estimate of a 12 day duration is too

optimistic;

> however, within this time, remission was seen in the case of Helen's

brother

> (esophageal cancer) and Mr. Mike Fernandez (prostate cancer); see pages 26

> to 28 of The Cure for Cancer? for details.

> > >

> > >4. Cancer - Does this procedure have any harmful side effects?

> > >

> > >No, Mr. Jerry Rollins, a member of cures for canceregroups, described

his

> experience thusly in a September 5, 1999 posting:

> > >

> > > " So....for better or worse I'm finished with the 12 day '

> Cure'. Except for the closely scheduled regimen it was not harmful in

anyway

> I can as yet determine. No kidney aches, bladder strain, headache, upset

> stomach....as a matter of fact I don't see how it can be me any good if

> there's not some suffering. Isn't that a fact of life...no gain without

> pain? Tuesday I'll have a PSA test so we'll all see. Won't it be fantastic

> if I can stop cantron, etc. and not worry about debilitating hormone

> followed by chemo. Of course the '12 day' is chemo but apparently a

harmless

> and quick one. It's nice to know there are many out there monitoring my

> progress. If it's worked all I'll need do is take what's necessary to keep

> my immune system in top shape. Best, JR "

> > >

> > >Unfortunately, Jerry was not helped by my procedure; however Helen's

> brother and Mike Fernandez were. This is why there is such a need for a

> scientifically controlled clinical trial.

> > >

> > >5. Cancer - Does the vitamin C aspect of my procedure have a medical

> name?

> > >

> > >Yes it does - 'Ascorbic Acid Flush'; see page 12 of The Cure for

Cancer?

> for details; however, in part:

> > >

> > > " Because vitamin C (ascorbic acid) promotes the healing of wounds and

> protects the body from bacterial infection, allergens, and other

pollutants,

> it is often beneficial to flush the body with ascorbic acid. This therapy

> can help treat chemical allergies and chemical poisoning, arsenic and

> radiation poisoning, influenza, and sprains, and it can help prevent other

> illnesses, including cancer and AIDS. "

> > >

> > >6. Cancer - Is a Nobel Prize winner still interested in the anti-Cancer

> possibilities of compounds containing Thioproline?

> > >

> > >I don't know. I have written to him several times but have never

received

> a response.

> > >

> > >Details - In 1994 and 1997 the Nobel Prize winner, Professor V.

> Schally, and his colleagues published articles which stated that

significant

> anti-Cancer results had been obtained in the laboratory with compounds

with

> incorporated Thioproline ('Tac'); compound RC-3950-II contains Tac; the

1994

> article states:

> > >

> > > " .....The best BN antagonists of this series, RC-3950-II.....,

inhibited

> gastrin-releasing peptide-stimulated growth of Swiss 3T3 cells with IC50

> values of 1 nM and 6 nM, respectively. Since antagonists of this class

> inhibit growth of various tumors in animal cancer models, some of them may

> have clinical applications. "

> > >

> > >(An abstract of this article appears in MedLine; type in 95108018;

click

> on to 'Cai RZ'.)

> > >

> > >If you were to obtain the complete article, 'Potent bombesin

antagonists

> with C-terminal Leu-psi(CH2-N)-Tac-NH2 or its derivatives, you would see

> that it concludes with these words:

> > >

> > > " .....Tac is a closed ring analog of Met and is more hydrophobic than

> Met. The replacement of Phe with Tac in reduced bond BN antagonists

produced

> improved Ki and IC50 values. BN antagonists such as RC-3950-II may have

> important therapeutic applications for the treatment of various

malignancies

> such as prostatic, gastric, and pancreatic cancer, small cell lung

> carcinoma, and other tumors (j.s.r. emphasis). "

> > >

> > >If a Nobel Prize winning scientist is interested in the possible

> effectiveness of compounds containing Thioproline as a Cancer cure,

> shouldn't the rest of the world be curious?

> > >

> > >However, in my opinion, Professor Schally's compound is too complex; it

> has a molecular mass of 1056.5; Thioproline is 133.18; consequently,

> couldn't the human body handle Thioproline easier than RC-3950-II?

> > >

> > >7. Cancer - Does MedLine classify Thioproline as being anti-cancerous?

> > >

> > >Yes, it does; type in 88098591; click on to 'Smeyers YG':

> > >

> > > " The charge distribution of anti-cancer molecules

> 4-thiazolidine-carboxylic acid (Thioproline)..... "

> > >

> > >8. Cancer - Do any foods contain Thioproline?

> > >

> > >Yes, the Shiitake mushroom is one of them; access MedLine; type in

> 91310113; click on to 'Tsuda M':

> > >

> > > " .....Recently, we found thioproline in various cooked foods, including

> cod and dried shiitake mushrooms..... "

> > >

> > >9. Cancer - Is Thioproline the most active constituent of the Shiitake

> mushroom?

> > >

> > >Yes it is -

> > >

> > >a. Access the website,

geocities.com/HotSprings/villa/1706/shiitake.html

> > >b. Refer to the table, 'Constituyentes Activos en el Shiitake'

> > >c. Look at the last entry of the table and you will see that

Thioproline

> (Thioprolina) has the highest designation (Fuente) - 27.

> > >

> > >10. Cancer - Do any other mushrooms contain Thioproline?

> > >

> > >No, they don't. MedLine contains over 11 million citations. If you type

> in the word combination thioproline mushrooms you will see that only one

> abstract appears, the 'Tsuda M' one from which I took this quote:

> > >

> > > " .....Recently, we found thioproline in various cooked foods, including

> cod and dried shiitake mushrooms..... "

> > >

> > >11. Cancer - Does traditional medicine recognize the potential

> anti-Cancer effectiveness of mushrooms?

> > >

> > >Yes, it does; access MedLine; type in 97264777; click on to 'Chang R';

> these words appear in the abstract (The research originated at the

> Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York

> City.):

> > >

> > > " Edible mushrooms such as shiitake may have important salutary effects

on

> health or even in treating disease. "

> > >

> > > " .....Although the data for this functional food class are not as

strong

> as those for other functional foods such as cruciferous vegetables,

because

> of their potential usefulness in preventing or treating serious health

> conditions as cancer, acquired immune deficiency syndrome (AIDS), and

> hypercholesterolemia, functional mushrooms deserve further serious

> investigation. "

> > >

> > >12. Cancer - In China and Japan, what have been the anti-Cancer results

> of using the Shiitake mushroom? My research has revealed -

> > >

> > > " ...in China and Japan, shiitake mushrooms have been used for hundreds

of

> years as cancer-fighting agents... " ; " Shiitake mushroom is believed to

> counteract stomach and cervical cancers...in October 1985...a new product

> containing the extract from shiitake mushroom had been approved by the

> Japanese government as an anti-cancerous agent. " ; the effectiveness of the

> shiitake mushroom " in treating cancer has been reported in a joint study

by

> the Medical Department of Koibe University and Nippon Kinoko Institute in

> Japan... " ; " ...And extracts from Shiitake mushroom are found to have

> anti-cancer properties. In fact, in Japan, extracts from this mushroom are

> one of the leading prescription treatments for cancer. "

> > >

> > >13. Cancer - What does my latest 8 " x11 " bulletin look like?

> > >

> > >Washington, D.C. -

> > >Tell the World about the

> > >anti-Cancer mushroom!

> > >In 1979 the essence of this mushroom was given to

> > >Cancer patients in Spain and remission was seen in

> > >breast, kidney, ovary, thyroid, and parotid cancer.

> > > " ...disappearance of evidence of

> > >cancer. " was noted!

> > >This report is in one of the World's greatest medical

> > >journals, 'The Lancet', Jan. 12, 1980, pp. 68-70.

> > >Watch 'Alternative Health Choices' - Treatments for

> > >Cancer, HIV/AIDS, Alcohol Abuse & Leukemia are

> > >discussed. Channel 4, 5:30 P.M., Wed., Portage, IN.

> > > S. , (219) 763-1933

> > >The mushroom is Shiitake; its essence is Thioproline.

> > >August 25, 2000

> > >

> > >End of bulletin -

> > >

> > >Physicians should be sued for Dereliction of Duty if they do not tell

> Cancer patients about the Shiitake mushroom.

> > >

> > >14. Cancer - Where can 98% pure Thioproline be obtained?

> > >

> > >Alfa Aesar Consult

> Alfa Aesar Online Catalog

> > >A Matthey Catalog Company, Inc.

L-Thiazolidine-4-carboxylic

> acid

> > >30 Bond Street

> (Thioproline)

> > >Ward Hill, Massachusetts 01835-8099 Item: A15033

> > >phone (800) 343-7276 & (978) 521-6300 CAS Number:

34592-47-7

> > >FAX (978) 521-6350 Prices: 10g

> $7.80; 50g $29.60; 250g $132.00.

> > >

> > >This company told me over the telephone that they will not sell to

> individuals. They will sell to companies who can submit the order on an

> official Purchase Order.

> > >

> > >15. Cancer - Should I receive a Nobel Prize in medicine if my proposed

> cure for Cancer proves true?

> > >

> > >Of course! - Let me tell you a story. Part of it is fictional, but all

of

> the medical statements are factual -

> > >

> > >In early 1979, Gosalvez discovered a chemical which he thought

> could cure Cancer - Thioproline.

> > >

> > >In the latter half of 1979, and his colleague,

Brugarolas,

> conducted a clinical trial with Thioproline at two separate medical

> facilities in Spain.

> > >

> > >Thioproline was the only chemical that was administered to the Cancer

> patients and and saw these results after they analyzed all

of

> the data which they had gathered together from the two medical

facilities -

> > >

> > > " .....Definite signs of activity were observed.....in other solid

> tumours, such as breast, renal, ovary, thyroid, and parotid cancer. "

> > >

> > > " .....Histological studies showed involution and transformation into

> low-grade malignancies and disappearance of evidence of cancer. "

> > >

> > > said to , " It is too bad that we did not achieve better

> results when more than half of our patients swallowed 5 mg/kg. daily of

> Thioproline. "

> > >

> > > " But , did you note? - One of the patients with kidney

> (renal-cell) cancer showed remission, and as you know, , this type

of

> cancer is almost invariably fatal. "

> > >

> > > " Wouldn't it be wonderful, , if we could somehow increase the

oral

> dosage from 5 mg/kg. to 40 mg/kg. daily, and see what results could be

> obtained?

> > >

> > >However, both and knew that this would be impossible

> because of Thioproline's toxicity; it is particularly harmful to the

Central

> Nervous System (CNS).

> > >

> > >Unfortunately, this question never occurred to , nor

anyone

> else in the scientific/medical community over the course of the past two

> decades -

> > >

> > > " Could Cancer patients swallow a certain substance which would

neutralize

> the toxicity of Thioproline, thus allowing them to swallow 'mega-doses' of

> Thioproline? "

> > >

> > >Yes - vitamin C neutralizes the toxicity of Thioproline.

> > >

> > >I am the only person in the world who has had this brilliant insight

> (Thanks to the epoch research of Dr. Herbert Sprince; see The Cure for

> Cancer?.)

> > >

> > >For this discovery, alone, I deserve a Nobel Prize in medicine. What if

> my proposed treatments are also effective for the following ailments -

> > >

> > >16. HIV/AIDS - Both the National Institutes of Health (NIH) and Centers

> for Disease Control (CDC) have acknowledged that HIV, the AIDS virus, can

be

> inactivated in the test tube by acetaldehyde.

> > >

> > >The 'cough inhibitor', L-2-Methylthiazolidine-4-carboxylic acid

(L-MTCA)

> is composed solely of L-cysteine (one half) and acetaldehyde (one half).

> > >

> > >L-Cysteic acid.H2O provided laboratory rats with 100% protection

against

> a lethal dose of acetaldehyde.

> > >

> > >Vitamin C affords phenomenal protection against the toxicity of

> Thiazolidine-4-carboxylic acid; in my opinion, vitamin C will likewise

> afford protection against the toxicity of

> L-2-Methylthiazolidine-4-carboxylic acid.

> > >

> > >Treatment for HIV/AIDS - 'mega-doses of L-MTCA & L-Cysteic acid.H2O &

> vitamin C (ascorbic acid).

> > >

> > >A little bit of history -

> > >

> > >Beginning in January, 1993, I started to suggest to the National

> Institutes of Health (NIH) that I thought that acetaldehyde might prove to

> be an effective anti-HIV agent. Throughout 1993, four top echelon Health

> Officials of the NIH said I was wrong. However, I kept on suggesting the

> acetaldehyde idea to the NIH; consequently, the NIH re-evaluted

acetaldehyde

> and stated on August 9, 1995: " The fact that acetaldehyde inactivates the

> human immunodeficiency virus (HIV) in test tube experiements does not

> necessarily make it a good candidate for anti-HIV therapy in humans..... "

> > >

> > >HIV/AIDS & MGN-3 & Thioproline

> > >

> > >I am going to assume that MGN-3 contains Thioproline because its

website,

> www.mgn3.net states:

> > >

> > > " Discovered in Japan, MGN-3 is a rice bran complex which has been

> modified using enzymes from edible Shiitake mushrooms (j.s.r. - containing

> Thioproline?) to produce a compound called Arabinoxylane..... "

> > >

> > >MedLine contains over 11 million citations. Only one appears when MGN-3

> is typed in - 'Anti-HIV activity in vitro of MGN-3, an activated

> arabinoxylane from rice bran.' (98139860); click on to 'Ghoneum M'; the

> abstract concludes:

> > >

> > > " .....We conclude that MGN-3 possesses potent anti-HIV activity and in

> the absence of any notable side effects MGN-3 shows promise as an agent

for

> treating patients with AIDS. "

> > >

> > >If it is indeed contained in MGN-3, Thioproline could be the agent

> causing this good result.

> > >

> > >In MedLine, only one abstract appears when the word combination

> thioproline hiv, is typed in - 'Structure of HIV-1 protease with KNI-272,

a

> tight-binding transition-state analog containing allophenylnorstatine'

> (96173007); click on to 'Baldwin ET'; the passage begins:

> > >

> > > " BACKGROUND: HIV-1 protease (HIV PR), an aspartic protease, cleaves

> Phe-Pro bonds in the Gag and Gag-Pol viral polyproteins. Substrate-based

> peptide mimics constitute a major class of inhibitors of HIV PR presently

> being developed for AIDS treatment. One such compound, KNI-272, which

> incorporates allophenylnorstatine (Apns) - thioproline (Thp) in place of

> Phe-Pro, has potent antiviral activity and is undergoing clinical

> trials..... "

> > >

> > >However, my research indicates that a 'chemical cousin of Thioproline

> (Thiazolidine-4-carboxylic acid) might prove to be the more effective

> anti-HIV agent. The name of that 'cousin' is

> L-2-Methylthiazolidine-4-carboxylic acid (L-MTCA).

> > >

> > >Thioproline is composed of formaldehyde (one half) and L-cysteine (one

> half).

> > >

> > >L-MTCA is composed of acetaldehyde (one half) and L-cysteine (one

half).

> > >

> > >Both the National Institutes of Health (NIH) and Centers for Disease

> Control (CDC) have acknowledged that HIV, the virus which causes AIDS, can

> be inactivated in the test tube by acetaldehyde.

> > >

> > >Japanese scientists incorporated a form of acetaldehyde -

diethylacetal -

> into a compound: N-myristoyl glycinal diethylacetal (N-Myr-GOA), and

> achieved these results during two experiments -

> > >

> > >Access MedLine, type in 90121218, click on to 'Tashiro A'; the abstract

> concludes:

> > >

> > > " .....In this system, N-Myr-Goa substantially inhibited more than 90%

of

> the N-Myristoylation of p17 gag protein produced in the HIV-1-infected

MT-4

> cells. These results suggest that the N-myristoylation of p17 gag protein

of

> HIV-1 may be essential in its structural assembly or maturation. "

> > >

> > >Access MedLine, type in 89033966, click on to 'Shoji S'; the last

> sentence of the abstract states:

> > >

> > > " .....Of the N-Myr-compounds tested, N-Myr-GOA remarkably prevented the

> myristoylation of p19gag and p17gag..... "

> > >

> > >My colleague, Mrs. Ann Nickoloff, and I concluded:

> > >

> > > " The work of Tashiro, Shoji and Kubota has shown that the gag proteins

of

> HIV-1 (p17, p41 & Pr55) are specifically myristoylated in their amino

> termini - NH2.

> > >

> > >The NH2 terminal myristoylation of p17 was particularly inhibited by

> N-myristoyl glycinal diethylacetal (N-Myr-GOA). N-Myr-GOA may be regarded

as

> an inhibitor of protein N-Myristol Transferase.

> > >

> > >N-Myr-GOA substantially inhibited more than 90% of the N-Myristoylation

> of p17 Protein produced in the HIV-1 infected MT-4 cells.

> > >

> > >These results suggest that the N-Myristoylation of p17 gag Protein of

> HIV-1 may be essential in its structural assembly or maturation.

> > >

> > >The role of protein myristoylation has remained unknown so far, but

> protein myristoylation, especially of structure proteins of human

> retroviruses, may be very important for the proliferation and and capsid

> formation of viruses. "

> > >

> > > " In summary, N-Myr-GOA strongly inhibits myristoylation of the HIV-1

gag

> proteins p41 and Pr55 and severely inhibits the myristoylation of p17

> gag..... "

> > >

> > > S. : L-MTCA contains 'pure' acetaldehyde which is more

> soluble than diethylacetal.

> > >

> > >Consequently, in my estimation L-MTCA would be a more effective agent

> that N-Myr-GOA in causing the anti-myristoylation of HIV's gag proteins.

> > >

> > >To repeat: L-MTCA is composed of acetaldehyde (one half) and L-cysteine

> (one half).

> > >

> > >In laboratory experiments L-Cysteic acid.H2O afforded rats 100%

> protection against lethal doses of acetaldehyde.

> > >

> > >Vitamin C affords phenomenal protection against the toxicity of

> formaldehyde, and I think it would be similarly protective against the

> toxicity of acetaldehyde.

> > >

> > >In my opinion, people afflicted with HIV/AIDS should swallow L-MTCA &

> L-Cysteic acid.H2O & vitamin C.

> > >

> > >17. Alcohol Abuse - What is the most important chemical element which a

> habitual drinker of alcohol should include in his or her diet?

> > >

> > >Zinc - You always read that zinc should be included in the diet of a

> drinker; however, thus far no one has ever highlighted the reason.

Sometimes

> I think that only I and the Encyclopaedia Britannica are aware of this

fact:

> > >

> > > " As absorbed alcohol is passed through the liver by the circulating

> blood it is acted upon by ADH (alcohol dehydrogenase), a zinc-containing

> enzyme found chiefly in the liver cells..... " (Encyclopaedia Britannica,

> Macropaedia, 1974 Edition, Volume 1, page 438)

> > >

> > >If anyone finds any reference to this particular passage in all of the

> literature about alcoholism, would you please let me know about it.

> > >

> > >Isn't it logical to assume that a dietary deficiency of zinc might be

THE

> primary precursor to the development of alcoholism if a person is a

regular

> consumer of alcohol?

> > >

> > >Other useful tips if you are a habitual drinker of alcohol -

> > >

> > >Alcohol metabolizes (changes) into acetaldehyde which is highly

> poisonous.

> > >

> > > " It would be a good idea, too, to add vitamin B-6 or pyridoxine to the

> components of this antiacetaldehyde nutritional packet. Since pyridoxine

> plays a part in the metabolic conversion of amino acids, even a marginal

> deficiency of this vitamin might slow down the conversion of

> sulfur-containing amino acids. "

> > >

> > >a. " Pyridoxal phosphate (vitamin B-6) is normally protected from

> degradation by its binding to the amine group of lysine residues of

> proteins, including serum proteins and hemaglobin. Acetaldehyde may, by

> binding preferentially to these residues, displace pyridoxal phosphate and

> result in its in its increased destruction, and abnormally low blood

levels

> of this co-enzyme. "

> > >b. " Pancreatitis. the pancreas, a long slender organ that secretes

> insulin and digestive enzymes, lies below and to the left of the stomach.

An

> inflammation of this organ, or pancreatitis, has been produced by diets

> deficient in vitamin B-6. "

> > >c. The poisonous part of alcohol, acetaldehyde, unnaturally depletes

the

> body's supply of vitamin B-6.

> > >d. If you are a habitual drinker of alcohol you better include in your

> diet an above average amount of vitamin B-6; if you don't you could

develop

> pancreatitis.

> > >

> > > " ...the liver depends on vitamin C to produce an enzyme - alcohol

> dehydrogenase - that helps usher alcohol out of the bloodstream. The less

> vitamin C there is, the longer the body stays polluted. "

> > >

> > > " Pyridoxine (vitamin B-6) is water soluble and is excreted by the body

> within 8 hours of intake. It is necessary for the reproduction of

antibodies

> and red blood cells. It is believed to be important in the proper

absorption

> of another B vitamin, B-12. Some doctors suggest higher doses for pregnant

> or nursing women... "

> > >

> > > " Aside from a thiamin deficiency, excessive drinking can also cause a

> deficiency of vitamin B-6, a nutrient needed to transmit nerve impulses.

> Doctors report that even a mild deficiency of vitamin B-6 alters brain

waves

> and that a severe deficiency can cause convulsive seizures.

> > >

> > > " Pyridoxine, or vitamin B-6, seems to be destroyed by alcohol. Over 50

> percent of those who drink excessively seem to have deficiencies. "

> > >

> > >I think it would be a good idea to print a third warning on all

> containers of alcoholic beverages -

> > >

> > >(3) PROPER METABOLISM OF ALCOHOL REQUIRES THE INGESTION OF ABOVE

AVERAGE

> AMOUNTS OF ZINC, VITAMIN B-6 AND VITAMIN C.

> > >

> > >18. Lou Gehrig's Disease (ALS) Amyotrophic Lateral Sclerosis -

> > >

> > >a. " Some reasearchers believe that so-called familial ALS (that is,

> inherited ALS) is caused by a defective gene that prevents the body from

> producing a normal amount of an enzyme called superoxide dismutase (SOD). "

> > >b. " What really sets this powdered barley juice apart from other food

> supplements is the presence of many usable enzymes and chlorophyll. The

> anti-aging enzyme 'superoxide dismutase (SOD), is one of these. Dr.

> Cutler, a biologist at the National Institute of Aging has shown that

> life-span is directly proportional to the amount of SOD contained in the

> cells. Anti-oxidants such as SOD protect the body from toxic free

radicals. "

> > >c. Could powdered barley juice retard, or at least slow down, the

damage

> done to spinal neurons and thus lessen the severity of Lou Gehrig's

Disease?

> > >

> > >I submitted this idea to the ALS Foundation. They had never heard of it

> before.

> > >

> > >19. Macular Degeneration -

> > >

> > >a. " Ginkgo (Ginkgo Biloba), extracts have been used to stem

deteriorating

> vision in patients by maintaining adequate blood flow to the retina... "

> > >b. " Herbalists believe ginkgo may.....help reduce retinal damage from

> macular degeneration, a cause of blindness..... "

> > >c. " Many older people exhibit deficiencies in zinc, which normally

> appears in high concentrations in the retinal, particularly in the

> macula..... "

> > >

> > >Could an above average amount of ginkgo biloba and zinc in the diet

help

> to alleviate the severity of macular degeneration?

> > >

> > >20. Chronic Myelogenous Leukemia (CML) - If you type penicillamine

> leukemia into MedLine you will find that there are 24 entries which are

> devoted to this subject. I have found the following one to be the most

> interesting; the unique identifier number is 96273151; I have taken one

> sentence from it:

> > >

> > > " .....Human acute myelogenous leukemia cells were especially sensitive

to

> PSH plus copper..... " PSH is d-penicillamine.

> > >

> > >A relationship exists between Penicillamine and

Thiazolidine-4-carboxylic

> acid (Thioproline, Tac).

> > >

> > >The 1999 edition of the PHYSICIANS' DESK REFERENCE (PDR) states on page

> 1766 that penicillamine " reacts readily with formaldehyde or acetone to

form

> a thiazolidine-carboxylic acid.

> > >

> > >I will state unequivocally that the " thiazolidine-carboxylic acid "

which

> the PDR mentions is the same as Thioproline. I challenge the scientific

and

> medical community of the world to refute me.

> > >

> > >Since vitamin C (ascorbic acid) protects against the toxicity of

> Thioproline, might it also protect against the toxicity of penicillamine?

> > >

> > >On about October 12, 1999, I called Dr. Cathcart's office; I believe

Dr.

> Cathcart is a former associate of Dr. Linus ing; Dr. Cathcart's

website

> is www.orthomed.com and it reads:

> > >

> > > 'ORTHOMOLECULAR MEDICINE

> > > VITAMIN C

> > > ROBERT F. CATHCART, M.D.'

> > >

> > >and left this question - " Does vitamin C afford protection against the

> toxicity of penicillamine? "

> > >

> > >The next day Dr. Cathcart's secretary called me and said that " Dr.

> Cathcart doesn't have any personal experience with what you mentioned, but

> in theory he could see how vitamin C could protect against penicillamine. "

> > >

> > >a. A scientific fact - Human acute myelogenous leukemia cells are

> especially sensitive to d-penicillamine plus copper.

> > >b. A scientific opinion - vitamin C could possibly protect against

> penicillamine.

> > >c. A scientific hypothesis - 'Mega-doses' of d-penicillamine plus

copper

> and vitamin C will cure chronic myelogenous leukemia. j.s.r.

> > >

> > >

> > >

> > >

> > >

> > >

> > >

> > >

> > >

> > >

> > >

> > >

> > >

> > >

> > >

> > >

> > >

> > >

> > >

> > >

> > >

> > >

> > >

> > >

> > >

> > >

> > >

> > >

> > >

> > >

> > >

> > >

> > >

> >

> >

>

>

> Get HUGE info at http://www.cures for cancer.ws, and post your own links there.

Unsubscribe by sending email to cures for cancer-unsubscribeegroups or by

visiting http://www.bobhurt.com/subunsub.mv

>

[Guest guest]

Thioproline - Healing power of Mushroom

www.ighawaii.com/naturally/newsletter/mushroom.html

QUOTE:

" As a food only, mushrooms are quite extraordinary. They contain a

broad range of vitamins, minerals and complete protein with all

essential amino acids. The Greeks and Romans ate them for the strength

they believed they produced for battle.

" In this regards the Reishi, Shiitake, Maitake, Cordyceps and

Coriolus mushrooms are of particular interest. These mushrooms produce

a variety of complex compounds such as betaglucans, from which most

of the health benefits are believed to be derived.

" Some of the specifically active biochemicals include lentinan,

eritadenine, heteroglycan, protein conjugates, and thioproline. These

biologically active compounds have been shown in controlled scientific

studies to increase survival in gastric cancer patients, to have

antibacterial, antiviral and antiparasitic action, to be

immunomodulatory, to improve blood lipid profiles, to block the

carcinogenic activity of N-nitroso compounds, to improve liver

function in hepatitis patients and even to inhibit the human

immunodeficiency virus. They have also been demonstrated to enhance

protein synthesis, help the liver detoxify, stimulate and regulate

the cardiovascular and respiratory systems, protect against radiation,

have anti-thrombotic activity, serve as biological response modifiers

- and improve muscular dystrophy.

" In searching the patent literature I have discovered that various

mushrooms and isolated compounds from them are a part of patented

products and processes such as antitumor preparations, liver

stimulants, hypotensive preparations, liver stimulants, hypotensives

preparations, hypocholesterolemic preparations, hypoglycemic

preparations, chronic bronchitis treatments, immunologic agents,

Alzheimer's Disease treatments, antibiotic-bacteriolytic enzymes,

antimutagens, skin preparations, hair tonics, bath preparations,

beverages, bone formation accelerators, and postoperative

treatments.

" The exact mechanism of action of medicinal-type mushrooms is only

now beginning to be elucidated. Much of the activity, however, is

likely due to the complex polysaccharides such as the beta-glucans which

have cell surface activity. This interplay of mushrooms with

polysaccharides on tissue-cell surfaces which affect cell-to-cell,

tissue-to-tissue communication via cytokines and other biochemical

intermediaries, along with the broad nutritional value of the

mushrooms, is likely the key to the myriad beneficial activities.

" The health enhancing potential of these mushrooms is quite

" extraordinary. It is for this reason that various types of mushrooms

have been incorporated into some of the Wysong supplements, such as

Immulyn (immune system nutrition)...

" Maitake mushroom, one of the ingredients in Immulyn, has been

approved by the FDA for a phase II pilot study. The research will focus on

the 1,3 and 1,6 beta glucan fractions on late stage III or early state

IV adenocarcinomas of the breast and prostate.

From Wysong Health Letter

Shiitake

The Shiitake mushroom is the SECOND most widely cultivated mushroom

in the world and is both a prized medicine as well as a culinary

delight.

Because of its traditional use in folk medicine and its

availability, it has been the subject of intense research. Cochran's

review of medicinal mushrooms, " Medical Effects " (Biology and

Cultivation of Edible Mushrooms, Academic Press, 1978), list Shiitake

as having antifungal, anti-tumor, and antiviral effects.

Shiitake also have the ability to lower high blood pressure and

cholesterol levels, and may also prevent the increase of chromosomal

damage induced by anti-cancer drugs.

Additionally, Shiitake contains all eight essential amino acids in

better proportions than soy beans, meat, milk, or eggs as well as a

good blend of vitamins and minerals including vitamins A, B, B12, C, D

and Niacin. Shiitake produces a fat-absorbing compound which aids in

weight reduction. Delicious to eat and good for you -

==================================================================

New Page 1

...Description Thioproline is an endogenous Sulfuric (sulfhydryl)

Amino Acid...

...Penicillin). Health Benefits of Thioproline Detoxification...

www.wellnessamerica.com/subscriber/amino_acids/Thioproline.htm - 3k

QUOTE

Description

Thioproline is an endogenous Sulfuric (sulfhydryl) Amino Acid that

is produced within the Liver. The chemical structure of TCA is similar

to that of Penicillin (although its activity within the body differs

to that of Penicillin).

Health Benefits of Thioproline

Detoxification

Thioproline prevents the conversion of dietary Nitrites to

Nitrosamines (by trapping them within the body, allowing their

excretion via the Urine) (Abstracts).

Metabolism

Thioproline possesses Antioxidant properties.

Thioproline protects the Liver from the damage induced by various

toxins:

- Thioproline protects the Liver against the toxic effects of

Acetaminophen overdose.

- Thioproline protects the Liver against the toxic effects of

Tetracycline.

- Thioproline protects the Liver against the toxic effects of

Alcohol

(ethanol).

Dietary Sources of Thioproline

Fungi: Shiitake Mushroom *

Seafood: Cod * Thioproline is not present in raw or dried Shiitake

Mushrooms, but is produced when Shiitake Mushrooms are boiled in Water

for at least 5 minutes or when Shiitake Mushrooms are soaked in cold

Water for 30 minutes. Using either of these processes, the Thioproline

content of Shiitake Mushrooms increases to 700 mcg per 100 mg.

Furthermore, if Shiitake Mushrooms are cooked together with

Cysteine-rich foods (such as Chicken Liver) the Thioproline produced

from Shiitake Mushrooms rises to 10 mg per 100 grams (of Shiitake

Mushrooms).

Clinical Availability of Thioproline

Synthetic Thioproline has been synthesized and patented; and is

classified as a Pharmaceutical Drug.

Chemical Data

Chemical Name: L-(-)-Thiazolidine-4-carboxylic acid

Molecular Formula: C4H7NO2S

UNQUOTE

I would opt for the natural Thioproline, rather than its synthetic

form, since some synthetic compounds have been found to do harm to the

body.

Joy

--------------------------------------------------------------------

>

>Essential Fatty Acids have been overlooked in modern nutritional shorthand

>advice to " avoid " certain foods-usuallu fats with unintended consequences. I

>received the following E mail fro Joyce Inouye who was blocked from the

>cures for cancer forum so I'm submitting her dialogue with ,

>evidently thioproline can help mitigate against these deficiencies.

> Arnold Gore

> Re: Anti-Cancer research missing from Federal Archive.

>

>

>>

>> " THE PLASMA MEMBRANE AS A TARGET IN ANTICANCER CHEMOTHERAPY " .

>>

>> This is well known in immunology. The MEMBRANE is the key to

>> successful IMMUNITY. This is why we need Essential Fatty Acids--it is

>> used to make part of the Cell Membrane. I'm afraid the " fat scare " has

>> caused many people to become sick, and the cause is lack of Essential

>> Fatty Acids for healthy Membranes. The medical profession has scared

>> people from taking the Vital Oils and Fats needed for life. The

>> IMMUNE SYSTEM is a Communication System, and the greater part of

>> COMMUNICATION happens at the MEMBRANE.

>>

>> As I recall, STRESS can cause the body to produce bad

>> nitrogen-containing compounds which cause normal cells to transform

>> into cancer cells. These nitrogen compounds damage the Cell Membrane,

>> which is part of the reason for carcinogenesis. Thioproline will help

>> render some of these bad chemicals harmless. People who harbor

>> unforgiveness and resentments produce bad chemicals by the brain,

>> which interact with the MEMBRANE of Immune Cells.

>>

>> There is a BRAIN-IMMUNE-HORMONE interaction which may control how sick

>> or healthy you are. God says to love, forgive, and bless others, and

>> to think thoughts which are pure, good, holy, true, of good report,

>> etc. These thoughts produce good chemicals in the brain, which also

>> interact with the MEMBRANE of Immune Cells, strengthening the Immune

>> System and the Body.

>>

>> There seems to be a dedicated effort to hide from the public the

>> things that will keep people healthy. God's Laws for HEALTH is one.

>> His laws tell us how to think to keep healthy, and which foods to eat

>> (e.g. raw fruits, vegetables, seeds, etc.) to keep us from getting

>> diseases.

>>

>> Joy

>> --------------------------------------------------------------------

>>

>>

>> >

>>

>> >

>> >September 10, 2000

>> >

>> > " The only good is knowledge and the only evil is ignorance. " Socrates

>> >

>> >My research describes treatments for Cancer, HIV/AIDS, Alcohol Abuse, Lou

>Gehrig's Disease (ALS), Macular Degeneration & Chronic Myelogenous Leukemia

>(CML).

>> >

>> >Representative J. Visclosky

>> >2313 Rayburn Building

>> >Washington, D.C. 20515-1401

>> >

>> >Dear Congressman Visclosky,

>> >

>> >The report of one of the most astounding anti-Cancer discoveries of the

>20th Century is missing from an official archive of the United States

>Government.

>> >

>> >If you type www.ncbi.nlm.nih.gov/pubmed into The Internet you will see

>that this information first appears -

>> >

>> > " PubMed is the National Library of Medicine's search service that

>provides access to over 11 million citations in MEDLINE, PreMEDLINE, and

>other related databases, with links to participating online journals. "

>> >

>> >Congressman Visclosky, the abstract of the March, 1979 article written by

> Gosalvez does not appear in 'MedLine'; the title of the article is,

> " THE PLASMA MEMBRANE AS A TARGET IN ANTICANCER CHEMOTHERAPY " .

>> >

>> >In this article Gosalvez concluded, from his laboratory research,

>that the chemical, Thiazolidine-4-carboxylic acid (Thioproline), " .....could

>represent the first non-cytotoxic anticancer agent which has the plasma

>membrane as target. "

>> >

>> >Indeed, a few months later in the latter half of 1979 a clinical trial

>conducted by Gosalvez and his colleague, Brugarolas, revealed

>this result after Thioproline had been administered to Cancer patients in

>Spain -

>> >

>> > " .....Histological studies showed involution and transformation into

>low-grade malignancies and disappearance of evidence of cancer. "

>> >

>> >(An abstract of this research does appear in MedLine - UI:80098547.)

>> >

>> >Congressman Visclosky, the March, 1979 research of Gosalvez was

>funded by the U.S. National Cancer Institute under Contract NO1-CM-53792.

>> >

>> >Did someone at the U.S. National Cancer Institute determine that the

>result of the March, 1979 research was not important enough to be included

>in MedLine?

>> >

>> >Congressman Visclosky, could Dr. Varmus afford us an explanation of this

>omission and tell us what he is prepared to do to correct this oversight?

>> >

>> >Congressman Visclosky, I was somewhat surprised to see that the U.S.

>National Cancer Institute did not explore further the results of the

>Gosalvez/Brugarolas research with additional clinical trials upon human

>beings. Instead, this agency was content to fund research upon rats and

>mice.

>> >

>> >Congressman Visclosky, included in this envelope is a copy of my November

>7, 1999 letter to Dr. Varmus; in that letter is this passage:

>> >

>> >Text -

>> >

>> >Dr. Varmus, I see that after the Spanish research was published the

>National Cancer Institute supported in part (grant CA-24543) and contract

>No1-CM-97278, Division of Cancer Treatment, Study Number 35, " Pharmacologic

>and Toxicologic Evaluation of Thioproline: A Proposed Nontoxic Inducer of

>Reverse Transformation " , 'Cancer Treatment Reports', Vol. 64, No. 8-9,

>August/September 1980, pages 837-844. Its summary states:

>> >

>> > " The ability of thioproline to act as a nontoxic inducer of reverse

>transformation was examined. Thioproline was unable to effect reproducibly

>morphologic changes characteristic of the reverse transformed state in HeLa,

>WI-38VA13, C1300 neuroblastoma, and CHO-K1 cell lines. Reversal of

>transformed cells with dibutyryl cyclic AMP was, however, readily

>demonstated in both the CHO-K1 and C1300 cell lines. Thioproline produced

>severe, life threatening CNS toxicity in both mice and rats at levels far

>below those previously reported to be without any toxic effects. We conclude

>that not only is thioproline incapable of producing a reversal on the

>transformed state in HeLa and other cell lines in vitro, it is also a

>compound that must be described as a strongly CNS toxic agent. "

>> >

>> >Dr. Varmus, I am disappointed to see that the National Cancer Institute

>did not conduct a clinical trial to see what effect thioproline might have

>upon human beings, as was done in Spain in 1979.

>> >

>> >Dr. Varmus, I assume the National Cancer Institute (NCI) conducted

>meetings to compare and contrast the research which I have thus far cited.

>Am I over-looking any other important studies which the NCI may have taken

>into consideration?

>> >

>> >Dr. Varmus, are minutes of those meetings available which could be made

>public to the American populace?

>> >

>> >Dr. Varmus, on what basis did the NCI decide to discontinue efforts to

>investigate the possibilities of the Brugarolas/Gosalvez research? What was

>the key factor which abnegated interest in Thiazolidine-4-carboxylic acid

>(Thioproline) as an anti-cancer agent? Could it have been its toxicity?

>> >

>> >End of Text -

>> >

>> >Congressman Visclosky, I hope that Dr. Varmus will afford, at least to

>you, a response to the aforementioned passage.

>> >

>> >Congressman Visclosky, in the 'Dr. Varmus' letter I also state:

>> >

>> > " Dr. Varmus, since November, 1997, I have been proposing the combination

>of 'mega-doses' of Thiazolidine-4-carboxylic acid and vitamin C and 'above

>average' amounts of magnesium, zinc and manganese as an anti-cancer agent.

>> >

>> >I really would like to see some resolution to this matter. "

>> >

>> >Congressman Visclosky, after reviewing the data delineated in the Post

>Script of this letter, I hope that Dr. Varmus will see the compelling need

>to repeat the 1979 Spanish clinical trial.

>> >

>> >To repeat, with Thioproline, alone, this result was achieved in 1979 -

>> >

>> > " .....disappearance of evidence of cancer. "

>> >

>> >My research has revealed a most unusual fact of nature - vitamin C

>neutralizes the toxicity of Thioproline - thus - Cancer patients could

>swallow 'mega-doses' of Thioproline if they also swallowed, at the same

>time, 'mega-doses' of vitamin C.

>> >

>> >Yours truly, , jsr1936@..., P.O. Box H,

>Hobart, IN 46342, (219) 763-1933

>> >

>> >Copies to -

>> >

>> >Donna E. Shalala, Ph.D., Secretary of Health and Human Services,

>Washington, D.C.

>> >Harold E. Varmus, M.D., Director, National Institutes of Health (NIH),

>Bethesda, land

>> > Klausner, M.D., Director, National Cancer Institute, (NCI),

>Bethesda, land

>> >Lake/Porter County Medical Society, Merrillville, Indiana

>> >

>> >Post Script -

>> >

>> >The following data might prove beneficial to anyone troubled by Cancer,

>HIV/AIDS, Alcohol Abuse, Lou Gehrig's Disease (ALS), Macular Degeneration &

>Chronic Myelogenous Leukemia (CML).

>> >

>> >More details can be found in my website, The Cure for Cancer?

>www.datadepo.com/cures for cancer/tac-cure.htm .

>> >

>> >Sometimes I will refer to 'MedLine'; this is the procedure to follow -

>access www.ncbi.nlm.nih.gov/pubmed, type in the Unique Identifier (UI)

>number, then 'click on' to the name cited to 'bring up' the full abstract.

>> >

>> >1. Cancer - Why is the following information missing from the National

>Archive, 'MedLine'?

>> >

>> >There are over 11 million citations in 'MedLine'.

>> >

>> >MedLine is The Internet resource of the National Library of Medicine.

>> >

>> > Gosalvez wrote 4 articles in 1979 which are cited in MedLine -

>> >

>> >1. January, 1979 - " Inhibition of sodium-potassium-activated adenosine

>5'-triphosphatase and ion transport by adriamycin. "

>> >2. February, 1979 - " A possible pathogenic mechanism for the induction of

>rotenone tumours. "

>> >3. February, 1979 - " Restoration of 'contact inhibition' in tumour cells

>in tissue culture by treatment with thiazolidine-4-carboxylic acid. "

>> >4. May, 1979 - " Early clinical trial with quelamycin. "

>> >

>> >However, Gosalvez wrote a 5th article in 1979, and it is not cited

>in MedLine.

>> >

>> >A little bit of history - The U.S. National Cancer Institute under

>Contract NO1-CM-53792 had funded the Cancer research of Gosalvez; at

>the time he was a researcher at the Bioquimica Experimental, Clinica Puerta

>de Hierro, Madrid-35, Spain.

>> >

>> >The result of Gosalvez' research was published in the March, 1979,

>issue of the 'Proceedings of the American Association for Cancer Research',

>Volume 20, page 17.

>> >

>> >These words of Gosalvez appear in 'AACR ABSTRACTS, 1979', No. 68

>(All bold face emphasis is mine.):

>> >

>> > " .....The screening included the test of compounds: 1) in cell capping of

>immuno-globulins; 2) in the differentiation of the mold Dictyostelium

>discoideum and 3) in the restoration of contact inhibition of Hela cells in

>tissue culture. One compound out of 500, thiazolidine-4-carboxylic acid

>(j.s.r. - Thioproline), was active in the three screening steps and was able

>to restore contact inhibition in Hela cells in tissue culture. This compound

>has been brought to the clinics in Spain in patients of advanced metastasic

>progressing cancer, under the name of Norgamem. Norgamem could represent the

>first non-cytotoxic anticancer agent which has the plasma membrane as

>target. "

>> >

>> >To double check and confirm the fact that this 5th article of

>Gosalvez is not contained in MedLine, type in the title of the article, 'THE

>PLASMA MEMBRANE AS A TARGET IN ANTICANCER CHEMOTHERAPY', into 'Search PubMed

>for', click on to 'Go', and these words will appear - " No items found " .

>> >

>> >In fact, none of the Divisions of MedLine (PubMed, Protein, Nucleotide,

>Structure, Genome, Popset, Taxonomy) contain a reference to this 5th article

>of Gosalvez which was published in March, 1979.

>> >

>> >The subsequent clinical trial in Spain, in the latter half of 1979,

>revealed these results after Thioproline had been administered to human

>beings with Cancer -

>> >

>> > " .....Definite signs of activity were observed.....in other solid

>tumours, such as breast, renal, ovary, thyroid, and parotid cancer. "

>> >

>> > " .....Histological studies showed involution and transformation into

>low-grade malignancies and disappearance of evidence of cancer. "

>> >

>> >The aforementioned words appear in one of the world's foremost medical

>journals, 'The Lancet', January 12, 1980, pages 68 to 70.

>> >

>> >2. Cancer - What do I think of the scientific/medical research which

>occurred between 1980 and 1983 relative to the result of the 1979 Spanish

>clinical trial - " .....disappearance of evidence of cancer. "

>> >

>> >Refer to the 'Dr. Varmus' letter; this letter chronicles the puny, paltry

>effort put forth by the scientific community from 1980 to 1983 to take

>advantage of this marvelous result. The medical community settled for

>scanty, skimpy research in reaching its decision to abandon interest in

>Thioproline as a possible Cancer cure.

>> >

>> >As a result of this feeble, futile, feckless, abortive research effort, a

>negative light was cast upon Thioproline which the world has been doomed to

>live with throughout the past two decades.

>> >

>> >Note these poignant words of Gosalvez in the 'Dr. Varmus' letter:

>> >

>> > " .....However, reports of our later work given at scientific meetings or

>in the pipeline, confirm that thioproline does induce reverse transformation

>and that the whole concept, despite its complexities, is promising. "

>> >

>> >3. Cancer - Would it be difficult to repeat the 1979 Spanish clinical

>trial?

>> >

>> >Not at all! The parameters of the 1979 trial were fairly simple (page 68,

>'The Lancet', January 12, 1980) -

>> >

>> > " The criteria used in the selection of patients were: pathological

>diagnosis of advanced cancer resistant to treatment; physical condition

>allowing outpatient care; measurable tumour for evaluation of the response;

>no other cancer treatment in the 4 weeks before, or during thioproline

>treatment; and informed consent by patients. "

>> >

>> > " Clinical assessment included history and examination, measurement of

>tumours, chest X-ray, ECG, complete blood counts, liver profile, and urine

>analysis. These assessments were made before treatment began, and every 1-3

>weeks during treatment. "

>> >

>> >In the 1979 trial some patients were injected with Thioproline, 20 to 40

>mg/kg. daily, and some patients swallowed it, 5 mg/kg. daily.

>> >

>> >I have discovered a unique fact of nature - vitamin C affords phenomenal

>protection against the toxicity of Thioproline.

>> >

>> >Consequently, a new clinical trial could determine what the effect would

>be on Cancer patients if they swallowed ' mega-doses' of Thioproline and

>vitamin C; in my opinion, the 'mega-dose' amount of Thioproline could be as

>high as 40 mg/kg. daily (maybe more!).

>> >

>> >This is not to say that the patients would have to begin immediately with

>a 40 mg/kg. daily dosage of Thioproline -

>> >

>> >On day 1 the patients would swallow 10 mg/kg. of Thioproline; if no

>problems develop -

>> >On day 2 the patients would swallow 15 mg/kg. of Thioproline; if no

>problems develop -

>> >On day 3 the patients would swallow 20 mg/kg. of Thioproline; if no

>problems develop -

>> >On day 4 the patients would swallow 25 mg/kg. of Thioproline; if no

>problems develop -

>> >On day 5 the patients would swallow 30 mg/kg. of Thioproline; if no

>problems develop -

>> >On day 6 the patients would swallow 35 mg/kg. of Thioproline; if no

>problems develop -

>> >On day 7 the patients would swallow 40 mg/kg. of Thioproline.

>> >

>> >Thus, within a week, the administrators of the Cancer clinical trial

>could determine whether patients could safely swallow 40 mg/kg. daily of

>Thioproline (along with their vitamin C).

>> >

>> >Further details can be found on pages 7 to 9 (left hand side pagination)

>of The Cure for Cancer?. My estimate of a 12 day duration is too optimistic;

>however, within this time, remission was seen in the case of Helen's brother

>(esophageal cancer) and Mr. Mike Fernandez (prostate cancer); see pages 26

>to 28 of The Cure for Cancer? for details.

>> >

>> >4. Cancer - Does this procedure have any harmful side effects?

>> >

>> >No, Mr. Jerry Rollins, a member of cures for canceregroups, described his

>experience thusly in a September 5, 1999 posting:

>> >

>> > " So....for better or worse I'm finished with the 12 day '

>Cure'. Except for the closely scheduled regimen it was not harmful in anyway

>I can as yet determine. No kidney aches, bladder strain, headache, upset

>stomach....as a matter of fact I don't see how it can be me any good if

>there's not some suffering. Isn't that a fact of life...no gain without

>pain? Tuesday I'll have a PSA test so we'll all see. Won't it be fantastic

>if I can stop cantron, etc. and not worry about debilitating hormone

>followed by chemo. Of course the '12 day' is chemo but apparently a harmless

>and quick one. It's nice to know there are many out there monitoring my

>progress. If it's worked all I'll need do is take what's necessary to keep

>my immune system in top shape. Best, JR "

>> >

>> >Unfortunately, Jerry was not helped by my procedure; however Helen's

>brother and Mike Fernandez were. This is why there is such a need for a

>scientifically controlled clinical trial.

>> >

>> >5. Cancer - Does the vitamin C aspect of my procedure have a medical

>name?

>> >

>> >Yes it does - 'Ascorbic Acid Flush'; see page 12 of The Cure for Cancer?

>for details; however, in part:

>> >

>> > " Because vitamin C (ascorbic acid) promotes the healing of wounds and

>protects the body from bacterial infection, allergens, and other pollutants,

>it is often beneficial to flush the body with ascorbic acid. This therapy

>can help treat chemical allergies and chemical poisoning, arsenic and

>radiation poisoning, influenza, and sprains, and it can help prevent other

>illnesses, including cancer and AIDS. "

>> >

>> >6. Cancer - Is a Nobel Prize winner still interested in the anti-Cancer

>possibilities of compounds containing Thioproline?

>> >

>> >I don't know. I have written to him several times but have never received

>a response.

>> >

>> >Details - In 1994 and 1997 the Nobel Prize winner, Professor V.

>Schally, and his colleagues published articles which stated that significant

>anti-Cancer results had been obtained in the laboratory with compounds with

>incorporated Thioproline ('Tac'); compound RC-3950-II contains Tac; the 1994

>article states:

>> >

>> > " .....The best BN antagonists of this series, RC-3950-II....., inhibited

>gastrin-releasing peptide-stimulated growth of Swiss 3T3 cells with IC50

>values of 1 nM and 6 nM, respectively. Since antagonists of this class

>inhibit growth of various tumors in animal cancer models, some of them may

>have clinical applications. "

>> >

>> >(An abstract of this article appears in MedLine; type in 95108018; click

>on to 'Cai RZ'.)

>> >

>> >If you were to obtain the complete article, 'Potent bombesin antagonists

>with C-terminal Leu-psi(CH2-N)-Tac-NH2 or its derivatives, you would see

>that it concludes with these words:

>> >

>> > " .....Tac is a closed ring analog of Met and is more hydrophobic than

>Met. The replacement of Phe with Tac in reduced bond BN antagonists produced

>improved Ki and IC50 values. BN antagonists such as RC-3950-II may have

>important therapeutic applications for the treatment of various malignancies

>such as prostatic, gastric, and pancreatic cancer, small cell lung

>carcinoma, and other tumors (j.s.r. emphasis). "

>> >

>> >If a Nobel Prize winning scientist is interested in the possible

>effectiveness of compounds containing Thioproline as a Cancer cure,

>shouldn't the rest of the world be curious?

>> >

>> >However, in my opinion, Professor Schally's compound is too complex; it

>has a molecular mass of 1056.5; Thioproline is 133.18; consequently,

>couldn't the human body handle Thioproline easier than RC-3950-II?

>> >

>> >7. Cancer - Does MedLine classify Thioproline as being anti-cancerous?

>> >

>> >Yes, it does; type in 88098591; click on to 'Smeyers YG':

>> >

>> > " The charge distribution of anti-cancer molecules

>4-thiazolidine-carboxylic acid (Thioproline)..... "

>> >

>> >8. Cancer - Do any foods contain Thioproline?

>> >

>> >Yes, the Shiitake mushroom is one of them; access MedLine; type in

>91310113; click on to 'Tsuda M':

>> >

>> > " .....Recently, we found thioproline in various cooked foods, including

>cod and dried shiitake mushrooms..... "

>> >

>> >9. Cancer - Is Thioproline the most active constituent of the Shiitake

>mushroom?

>> >

>> >Yes it is -

>> >

>> >a. Access the website, geocities.com/HotSprings/villa/1706/shiitake.html

>> >b. Refer to the table, 'Constituyentes Activos en el Shiitake'

>> >c. Look at the last entry of the table and you will see that Thioproline

>(Thioprolina) has the highest designation (Fuente) - 27.

>> >

>> >10. Cancer - Do any other mushrooms contain Thioproline?

>> >

>> >No, they don't. MedLine contains over 11 million citations. If you type

>in the word combination thioproline mushrooms you will see that only one

>abstract appears, the 'Tsuda M' one from which I took this quote:

>> >

>> > " .....Recently, we found thioproline in various cooked foods, including

>cod and dried shiitake mushrooms..... "

>> >

>> >11. Cancer - Does traditional medicine recognize the potential

>anti-Cancer effectiveness of mushrooms?

>> >

>> >Yes, it does; access MedLine; type in 97264777; click on to 'Chang R';

>these words appear in the abstract (The research originated at the

>Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York

>City.):

>> >

>> > " Edible mushrooms such as shiitake may have important salutary effects on

>health or even in treating disease. "

>> >

>> > " .....Although the data for this functional food class are not as strong

>as those for other functional foods such as cruciferous vegetables, because

>of their potential usefulness in preventing or treating serious health

>conditions as cancer, acquired immune deficiency syndrome (AIDS), and

>hypercholesterolemia, functional mushrooms deserve further serious

>investigation. "

>> >

>> >12. Cancer - In China and Japan, what have been the anti-Cancer results

>of using the Shiitake mushroom? My research has revealed -

>> >

>> > " ...in China and Japan, shiitake mushrooms have been used for hundreds of

>years as cancer-fighting agents... " ; " Shiitake mushroom is believed to

>counteract stomach and cervical cancers...in October 1985...a new product

>containing the extract from shiitake mushroom had been approved by the

>Japanese government as an anti-cancerous agent. " ; the effectiveness of the

>shiitake mushroom " in treating cancer has been reported in a joint study by

>the Medical Department of Koibe University and Nippon Kinoko Institute in

>Japan... " ; " ...And extracts from Shiitake mushroom are found to have

>anti-cancer properties. In fact, in Japan, extracts from this mushroom are

>one of the leading prescription treatments for cancer. "

>> >

>> >13. Cancer - What does my latest 8 " x11 " bulletin look like?

>> >

>> >Washington, D.C. -

>> >Tell the World about the

>> >anti-Cancer mushroom!

>> >In 1979 the essence of this mushroom was given to

>> >Cancer patients in Spain and remission was seen in

>> >breast, kidney, ovary, thyroid, and parotid cancer.

>> > " ...disappearance of evidence of

>> >cancer. " was noted!

>> >This report is in one of the World's greatest medical

>> >journals, 'The Lancet', Jan. 12, 1980, pp. 68-70.

>> >Watch 'Alternative Health Choices' - Treatments for

>> >Cancer, HIV/AIDS, Alcohol Abuse & Leukemia are

>> >discussed. Channel 4, 5:30 P.M., Wed., Portage, IN.

>> > S. , (219) 763-1933

>> >The mushroom is Shiitake; its essence is Thioproline.

>> >August 25, 2000

>> >

>> >End of bulletin -

>> >

>> >Physicians should be sued for Dereliction of Duty if they do not tell

>Cancer patients about the Shiitake mushroom.

>> >

>> >14. Cancer - Where can 98% pure Thioproline be obtained?

>> >

>> >Alfa Aesar Consult

>Alfa Aesar Online Catalog

>> >A Matthey Catalog Company, Inc. L-Thiazolidine-4-carboxylic

>acid

>> >30 Bond Street

>(Thioproline)

>> >Ward Hill, Massachusetts 01835-8099 Item: A15033

>> >phone (800) 343-7276 & (978) 521-6300 CAS Number: 34592-47-7

>> >FAX (978) 521-6350 Prices: 10g

>$7.80; 50g $29.60; 250g $132.00.

>> >

>> >This company told me over the telephone that they will not sell to

>individuals. They will sell to companies who can submit the order on an

>official Purchase Order.

>> >

>> >15. Cancer - Should I receive a Nobel Prize in medicine if my proposed

>cure for Cancer proves true?

>> >

>> >Of course! - Let me tell you a story. Part of it is fictional, but all of

>the medical statements are factual -

>> >

>> >In early 1979, Gosalvez discovered a chemical which he thought

>could cure Cancer - Thioproline.

>> >

>> >In the latter half of 1979, and his colleague, Brugarolas,

>conducted a clinical trial with Thioproline at two separate medical

>facilities in Spain.

>> >

>> >Thioproline was the only chemical that was administered to the Cancer

>patients and and saw these results after they analyzed all of

>the data which they had gathered together from the two medical facilities -

>> >

>> > " .....Definite signs of activity were observed.....in other solid

>tumours, such as breast, renal, ovary, thyroid, and parotid cancer. "

>> >

>> > " .....Histological studies showed involution and transformation into

>low-grade malignancies and disappearance of evidence of cancer. "

>> >

>> > said to , " It is too bad that we did not achieve better

>results when more than half of our patients swallowed 5 mg/kg. daily of

>Thioproline. "

>> >

>> > " But , did you note? - One of the patients with kidney

>(renal-cell) cancer showed remission, and as you know, , this type of

>cancer is almost invariably fatal. "

>> >

>> > " Wouldn't it be wonderful, , if we could somehow increase the oral

>dosage from 5 mg/kg. to 40 mg/kg. daily, and see what results could be

>obtained?

>> >

>> >However, both and knew that this would be impossible

>because of Thioproline's toxicity; it is particularly harmful to the Central

>Nervous System (CNS).

>> >

>> >Unfortunately, this question never occurred to , nor anyone

>else in the scientific/medical community over the course of the past two

>decades -

>> >

>> > " Could Cancer patients swallow a certain substance which would neutralize

>the toxicity of Thioproline, thus allowing them to swallow 'mega-doses' of

>Thioproline? "

>> >

>> >Yes - vitamin C neutralizes the toxicity of Thioproline.

>> >

>> >I am the only person in the world who has had this brilliant insight

>(Thanks to the epoch research of Dr. Herbert Sprince; see The Cure for

>Cancer?.)

>> >

>> >For this discovery, alone, I deserve a Nobel Prize in medicine. What if

>my proposed treatments are also effective for the following ailments -

>> >

>> >16. HIV/AIDS - Both the National Institutes of Health (NIH) and Centers

>for Disease Control (CDC) have acknowledged that HIV, the AIDS virus, can be

>inactivated in the test tube by acetaldehyde.

>> >

>> >The 'cough inhibitor', L-2-Methylthiazolidine-4-carboxylic acid (L-MTCA)

>is composed solely of L-cysteine (one half) and acetaldehyde (one half).

>> >

>> >L-Cysteic acid.H2O provided laboratory rats with 100% protection against

>a lethal dose of acetaldehyde.

>> >

>> >Vitamin C affords phenomenal protection against the toxicity of

>Thiazolidine-4-carboxylic acid; in my opinion, vitamin C will likewise

>afford protection against the toxicity of

>L-2-Methylthiazolidine-4-carboxylic acid.

>> >

>> >Treatment for HIV/AIDS - 'mega-doses of L-MTCA & L-Cysteic acid.H2O &

>vitamin C (ascorbic acid).

>> >

>> >A little bit of history -

>> >

>> >Beginning in January, 1993, I started to suggest to the National

>Institutes of Health (NIH) that I thought that acetaldehyde might prove to

>be an effective anti-HIV agent. Throughout 1993, four top echelon Health

>Officials of the NIH said I was wrong. However, I kept on suggesting the

>acetaldehyde idea to the NIH; consequently, the NIH re-evaluted acetaldehyde

>and stated on August 9, 1995: " The fact that acetaldehyde inactivates the

>human immunodeficiency virus (HIV) in test tube experiements does not

>necessarily make it a good candidate for anti-HIV therapy in humans..... "

>> >

>> >HIV/AIDS & MGN-3 & Thioproline

>> >

>> >I am going to assume that MGN-3 contains Thioproline because its website,

>www.mgn3.net states:

>> >

>> > " Discovered in Japan, MGN-3 is a rice bran complex which has been

>modified using enzymes from edible Shiitake mushrooms (j.s.r. - containing

>Thioproline?) to produce a compound called Arabinoxylane..... "

>> >

>> >MedLine contains over 11 million citations. Only one appears when MGN-3

>is typed in - 'Anti-HIV activity in vitro of MGN-3, an activated

>arabinoxylane from rice bran.' (98139860); click on to 'Ghoneum M'; the

>abstract concludes:

>> >

>> > " .....We conclude that MGN-3 possesses potent anti-HIV activity and in

>the absence of any notable side effects MGN-3 shows promise as an agent for

>treating patients with AIDS. "

>> >

>> >If it is indeed contained in MGN-3, Thioproline could be the agent

>causing this good result.

>> >

>> >In MedLine, only one abstract appears when the word combination

>thioproline hiv, is typed in - 'Structure of HIV-1 protease with KNI-272, a

>tight-binding transition-state analog containing allophenylnorstatine'

>(96173007); click on to 'Baldwin ET'; the passage begins:

>> >

>> > " BACKGROUND: HIV-1 protease (HIV PR), an aspartic protease, cleaves

>Phe-Pro bonds in the Gag and Gag-Pol viral polyproteins. Substrate-based

>peptide mimics constitute a major class of inhibitors of HIV PR presently

>being developed for AIDS treatment. One such compound, KNI-272, which

>incorporates allophenylnorstatine (Apns) - thioproline (Thp) in place of

>Phe-Pro, has potent antiviral activity and is undergoing clinical

>trials..... "

>> >

>> >However, my research indicates that a 'chemical cousin of Thioproline

>(Thiazolidine-4-carboxylic acid) might prove to be the more effective

>anti-HIV agent. The name of that 'cousin' is

>L-2-Methylthiazolidine-4-carboxylic acid (L-MTCA).

>> >

>> >Thioproline is composed of formaldehyde (one half) and L-cysteine (one

>half).

>> >

>> >L-MTCA is composed of acetaldehyde (one half) and L-cysteine (one half).

>> >

>> >Both the National Institutes of Health (NIH) and Centers for Disease

>Control (CDC) have acknowledged that HIV, the virus which causes AIDS, can

>be inactivated in the test tube by acetaldehyde.

>> >

>> >Japanese scientists incorporated a form of acetaldehyde - diethylacetal -

>into a compound: N-myristoyl glycinal diethylacetal (N-Myr-GOA), and

>achieved these results during two experiments -

>> >

>> >Access MedLine, type in 90121218, click on to 'Tashiro A'; the abstract

>concludes:

>> >

>> > " .....In this system, N-Myr-Goa substantially inhibited more than 90% of

>the N-Myristoylation of p17 gag protein produced in the HIV-1-infected MT-4

>cells. These results suggest that the N-myristoylation of p17 gag protein of

>HIV-1 may be essential in its structural assembly or maturation. "

>> >

>> >Access MedLine, type in 89033966, click on to 'Shoji S'; the last

>sentence of the abstract states:

>> >

>> > " .....Of the N-Myr-compounds tested, N-Myr-GOA remarkably prevented the

>myristoylation of p19gag and p17gag..... "

>> >

>> >My colleague, Mrs. Ann Nickoloff, and I concluded:

>> >

>> > " The work of Tashiro, Shoji and Kubota has shown that the gag proteins of

>HIV-1 (p17, p41 & Pr55) are specifically myristoylated in their amino

>termini - NH2.

>> >

>> >The NH2 terminal myristoylation of p17 was particularly inhibited by

>N-myristoyl glycinal diethylacetal (N-Myr-GOA). N-Myr-GOA may be regarded as

>an inhibitor of protein N-Myristol Transferase.

>> >

>> >N-Myr-GOA substantially inhibited more than 90% of the N-Myristoylation

>of p17 Protein produced in the HIV-1 infected MT-4 cells.

>> >

>> >These results suggest that the N-Myristoylation of p17 gag Protein of

>HIV-1 may be essential in its structural assembly or maturation.

>> >

>> >The role of protein myristoylation has remained unknown so far, but

>protein myristoylation, especially of structure proteins of human

>retroviruses, may be very important for the proliferation and and capsid

>formation of viruses. "

>> >

>> > " In summary, N-Myr-GOA strongly inhibits myristoylation of the HIV-1 gag

>proteins p41 and Pr55 and severely inhibits the myristoylation of p17

>gag..... "

>> >

>> > S. : L-MTCA contains 'pure' acetaldehyde which is more

>soluble than diethylacetal.

>> >

>> >Consequently, in my estimation L-MTCA would be a more effective agent

>that N-Myr-GOA in causing the anti-myristoylation of HIV's gag proteins.

>> >

>> >To repeat: L-MTCA is composed of acetaldehyde (one half) and L-cysteine

>(one half).

>> >

>> >In laboratory experiments L-Cysteic acid.H2O afforded rats 100%

>protection against lethal doses of acetaldehyde.

>> >

>> >Vitamin C affords phenomenal protection against the toxicity of

>formaldehyde, and I think it would be similarly protective against the

>toxicity of acetaldehyde.

>> >

>> >In my opinion, people afflicted with HIV/AIDS should swallow L-MTCA &

>L-Cysteic acid.H2O & vitamin C.

>> >

>> >17. Alcohol Abuse - What is the most important chemical element which a

>habitual drinker of alcohol should include in his or her diet?

>> >

>> >Zinc - You always read that zinc should be included in the diet of a

>drinker; however, thus far no one has ever highlighted the reason. Sometimes

>I think that only I and the Encyclopaedia Britannica are aware of this fact:

>> >

>> > " As absorbed alcohol is passed through the liver by the circulating

>blood it is acted upon by ADH (alcohol dehydrogenase), a zinc-containing

>enzyme found chiefly in the liver cells..... " (Encyclopaedia Britannica,

>Macropaedia, 1974 Edition, Volume 1, page 438)

>> >

>> >If anyone finds any reference to this particular passage in all of the

>literature about alcoholism, would you please let me know about it.

>> >

>> >Isn't it logical to assume that a dietary deficiency of zinc might be THE

>primary precursor to the development of alcoholism if a person is a regular

>consumer of alcohol?

>> >

>> >Other useful tips if you are a habitual drinker of alcohol -

>> >

>> >Alcohol metabolizes (changes) into acetaldehyde which is highly

>poisonous.

>> >

>> > " It would be a good idea, too, to add vitamin B-6 or pyridoxine to the

>components of this antiacetaldehyde nutritional packet. Since pyridoxine

>plays a part in the metabolic conversion of amino acids, even a marginal

>deficiency of this vitamin might slow down the conversion of

>sulfur-containing amino acids. "

>> >

>> >a. " Pyridoxal phosphate (vitamin B-6) is normally protected from

>degradation by its binding to the amine group of lysine residues of

>proteins, including serum proteins and hemaglobin. Acetaldehyde may, by

>binding preferentially to these residues, displace pyridoxal phosphate and

>result in its in its increased destruction, and abnormally low blood levels

>of this co-enzyme. "

>> >b. " Pancreatitis. the pancreas, a long slender organ that secretes

>insulin and digestive enzymes, lies below and to the left of the stomach. An

>inflammation of this organ, or pancreatitis, has been produced by diets

>deficient in vitamin B-6. "

>> >c. The poisonous part of alcohol, acetaldehyde, unnaturally depletes the

>body's supply of vitamin B-6.

>> >d. If you are a habitual drinker of alcohol you better include in your

>diet an above average amount of vitamin B-6; if you don't you could develop

>pancreatitis.

>> >

>> > " ...the liver depends on vitamin C to produce an enzyme - alcohol

>dehydrogenase - that helps usher alcohol out of the bloodstream. The less

>vitamin C there is, the longer the body stays polluted. "

>> >

>> > " Pyridoxine (vitamin B-6) is water soluble and is excreted by the body

>within 8 hours of intake. It is necessary for the reproduction of antibodies

>and red blood cells. It is believed to be important in the proper absorption

>of another B vitamin, B-12. Some doctors suggest higher doses for pregnant

>or nursing women... "

>> >

>> > " Aside from a thiamin deficiency, excessive drinking can also cause a

>deficiency of vitamin B-6, a nutrient needed to transmit nerve impulses.

>Doctors report that even a mild deficiency of vitamin B-6 alters brain waves

>and that a severe deficiency can cause convulsive seizures.

>> >

>> > " Pyridoxine, or vitamin B-6, seems to be destroyed by alcohol. Over 50

>percent of those who drink excessively seem to have deficiencies. "

>> >

>> >I think it would be a good idea to print a third warning on all

>containers of alcoholic beverages -

>> >

>> >(3) PROPER METABOLISM OF ALCOHOL REQUIRES THE INGESTION OF ABOVE AVERAGE

>AMOUNTS OF ZINC, VITAMIN B-6 AND VITAMIN C.

>> >

>> >18. Lou Gehrig's Disease (ALS) Amyotrophic Lateral Sclerosis -

>> >

>> >a. " Some reasearchers believe that so-called familial ALS (that is,

>inherited ALS) is caused by a defective gene that prevents the body from

>producing a normal amount of an enzyme called superoxide dismutase (SOD). "

>> >b. " What really sets this powdered barley juice apart from other food

>supplements is the presence of many usable enzymes and chlorophyll. The

>anti-aging enzyme 'superoxide dismutase (SOD), is one of these. Dr.

>Cutler, a biologist at the National Institute of Aging has shown that

>life-span is directly proportional to the amount of SOD contained in the

>cells. Anti-oxidants such as SOD protect the body from toxic free radicals. "

>> >c. Could powdered barley juice retard, or at least slow down, the damage

>done to spinal neurons and thus lessen the severity of Lou Gehrig's Disease?

>> >

>> >I submitted this idea to the ALS Foundation. They had never heard of it

>before.

>> >

>> >19. Macular Degeneration -

>> >

>> >a. " Ginkgo (Ginkgo Biloba), extracts have been used to stem deteriorating

>vision in patients by maintaining adequate blood flow to the retina... "

>> >b. " Herbalists believe ginkgo may.....help reduce retinal damage from

>macular degeneration, a cause of blindness..... "

>> >c. " Many older people exhibit deficiencies in zinc, which normally

>appears in high concentrations in the retinal, particularly in the

>macula..... "

>> >

>> >Could an above average amount of ginkgo biloba and zinc in the diet help

>to alleviate the severity of macular degeneration?

>> >

>> >20. Chronic Myelogenous Leukemia (CML) - If you type penicillamine

>leukemia into MedLine you will find that there are 24 entries which are

>devoted to this subject. I have found the following one to be the most

>interesting; the unique identifier number is 96273151; I have taken one

>sentence from it:

>> >

>> > " .....Human acute myelogenous leukemia cells were especially sensitive to

>PSH plus copper..... " PSH is d-penicillamine.

>> >

>> >A relationship exists between Penicillamine and Thiazolidine-4-carboxylic

>acid (Thioproline, Tac).

>> >

>> >The 1999 edition of the PHYSICIANS' DESK REFERENCE (PDR) states on page

>1766 that penicillamine " reacts readily with formaldehyde or acetone to form

>a thiazolidine-carboxylic acid.

>> >

>> >I will state unequivocally that the " thiazolidine-carboxylic acid " which

>the PDR mentions is the same as Thioproline. I challenge the scientific and

>medical community of the world to refute me.

>> >

>> >Since vitamin C (ascorbic acid) protects against the toxicity of

>Thioproline, might it also protect against the toxicity of penicillamine?

>> >

>> >On about October 12, 1999, I called Dr. Cathcart's office; I believe Dr.

>Cathcart is a former associate of Dr. Linus ing; Dr. Cathcart's website

>is www.orthomed.com and it reads:

>> >

>> > 'ORTHOMOLECULAR MEDICINE

>> > VITAMIN C

>> > ROBERT F. CATHCART, M.D.'

>> >

>> >and left this question - " Does vitamin C afford protection against the

>toxicity of penicillamine? "

>> >

>> >The next day Dr. Cathcart's secretary called me and said that " Dr.

>Cathcart doesn't have any personal experience with what you mentioned, but

>in theory he could see how vitamin C could protect against penicillamine. "

>> >

>> >a. A scientific fact - Human acute myelogenous leukemia cells are

>especially sensitive to d-penicillamine plus copper.

>> >b. A scientific opinion - vitamin C could possibly protect against

>penicillamine.

>> >c. A scientific hypothesis - 'Mega-doses' of d-penicillamine plus copper

>and vitamin C will cure chronic myelogenous leukemia. j.s.r.

>> >

>> >

>> >

>> >

>> >

>> >

>> >

>> >

>> >

>> >

>> >

>> >

>> >

>> >

>> >

>> >

>> >

>> >

>> >

>> >

>> >

>> >

>> >

>> >

>> >

>> >

>> >

>> >

>> >

>> >

>> >

>> >

>> >

>>

>>

>

>

>Get HUGE info at http://www.cures for cancer.ws, and post your own links there.

Unsubscribe by sending email to cures for cancer-unsubscribeegroups or by

visiting http://www.bobhurt.com/subunsub.mv

>

>

[Guest guest]

In a message dated 09/12/2000 10:49:36 AM Eastern Daylight Time,

hamonicd@... writes:

<< I would like to know why Joyce was banned from this group!!! I enjoyed what

she had to offer and can not understand when someone is willing to offer so

much why we would want to bann them.

I don't remember her attacking folks character or calling people names, and

yet she is not allowed to post anymore. Maybe someone can shed alittle light

on the matter for me. There are not that many folks that contribute, and yet

when someone like Joyce dedicates their time to share we find a reason to

boot them off. It seems we fear those that want to talk about God and yet we

have no problem letting the devil slip in the back door.

So could someone please enlighten me and tell me why Joyce is no longer

allowed?

Debbie

----- Original Message -----

From: " Arnold Gore " <arnoldgore@...>

<cures for canceregroups>

Sent: Tuesday, September 12, 2000 5:44 AM >>

Some People Can't handle the truth of matters. Or don't like to be showed up.

Hey we could start our own cancer/cure/religion thing.......I use to do it

when I ran a BBS years ago. No Body got baned or kicked off my sytem. How

about you Debbie, I don't have the time to setup the links.

[Guest guest]

Tis a sad day that someone is banned for talking about God, there has to be

another reason. This is a joke right? Hey if I knew what to do maybe your

right, one that allows the full meal deal, cause without it all, nobody

really wins.

Re: Fw: Anti-Cancer research missing from Federal

Archive.

>

> In a message dated 09/12/2000 10:49:36 AM Eastern Daylight Time,

> hamonicd@... writes:

>

> << I would like to know why Joyce was banned from this group!!! I enjoyed

what

> she had to offer and can not understand when someone is willing to offer

so

> much why we would want to bann them.

>

> I don't remember her attacking folks character or calling people names,

and

> yet she is not allowed to post anymore. Maybe someone can shed alittle

light

> on the matter for me. There are not that many folks that contribute, and

yet

> when someone like Joyce dedicates their time to share we find a reason to

> boot them off. It seems we fear those that want to talk about God and yet

we

> have no problem letting the devil slip in the back door.

>

> So could someone please enlighten me and tell me why Joyce is no longer

> allowed?

> Debbie

> ----- Original Message -----

> From: " Arnold Gore " <arnoldgore@...>

> <cures for canceregroups>

> Sent: Tuesday, September 12, 2000 5:44 AM >>

> Some People Can't handle the truth of matters. Or don't like to be showed

up.

> Hey we could start our own cancer/cure/religion thing.......I use to do

it

> when I ran a BBS years ago. No Body got baned or kicked off my sytem. How

> about you Debbie, I don't have the time to setup the links.

>

> Get HUGE info at http://www.cures for cancer.ws, and post your own links there.

Unsubscribe by sending email to cures for cancer-unsubscribeegroups or by

visiting http://www.bobhurt.com/subunsub.mv

>

>

[Guest guest]

cancel subscription